Surgery (St Vincent's) - Theses

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    Techniques and technologies in joint replacement surgery: evaluating the value proposition of computer navigation in total knee replacement
    Trieu, Jason ( 2023-01)
    This thesis examined the role of computer navigation technologies in total knee replacement. I provide an overview of osteoarthritis and its impact across our healthcare system, the role of total knee replacement in the current management of knee osteoarthritis, and the value that total knee replacement delivers. I then examined the value proposition of computer navigation technologies used in total knee replacement, and the implications of this with respect to current surgical practices in total knee replacement. This was undertaken through a range of perspectives including patient-reported outcomes, complications, and resource utilisation. Finally, I evaluated the cost-effectiveness of computer navigation in total knee replacement surgery through a decision analysis using a Markov-based model informed by my preceding works. This body of work relied largely on the St Vincent’s Melbourne Arthroplasty Outcomes Registry (SMART), an institutional lower limb joint arthroplasty registry, based at St Vincent’s Hospital Melbourne under the stewardship of the University of Melbourne Department of Surgery and the Department of Orthopaedic Surgery at St Vincent’s Hospital Melbourne. I employed a variety of statistical and health economic strategies in performing these investigations and utilised propensity-score methods to ensure that the analyses conducted herein formed a valid and robust contribution to expanding the literature on techniques and technologies in joint replacement surgery.