Computing and Information Systems - Research Publications
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ItemPolicy-based vulnerability assessment for virtual organisations(Springer Berlin Heidelberg, 2012)
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ItemA distributed clinical data platform for physiological studies in the brain trauma domain(IEEE Computer Society, 2010)There are many serious and acute physiological conditions about which we have incomplete medical knowledge that can support optimal healthcare intervention. To develop effective treatments a wealth of clinical data is required for collection, analysis and feedback. Such data often does exist but is typically held in a variety of different formats and locations. This paper describes the EU FP7-funded Avert-IT project (www.avert-it.org), which has developed an integrated, real-time physiological data grid infrastructure (HypoNet) to address the specific issue of prediction of hypotensive events in the brain trauma domain and is currently being used as part of a large multi-centre clinical trial. The implementation and application of the HypoNet system is described here.
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ItemTowards an e-Infrastructure for urban research across Australia(IEEE, 2011-12-01)
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ItemE-infrastructure support for nanoCMOS device and circuit simulations(ACTA Press, 2010)The UK e-Science EPSRC pilot project Meeting the Design Challenges of nanoCMOS Electronics (nanoCMOS – www.nanocmos.ac.uk) was funded to address the challenges facing the global electronics semiconductor industry caused by the decreasing size of Complementary Metal Oxide Semiconductor (CMOS) transistors and the atomic variability present in devices manifest at these dimensions. Fundamental problems to be addressed include the modelling, understanding and predicting the effect of differences in the atomic structure of devices on their behaviour, and then using this information to guide electronic circuit and system designers who utilise CMOS components. In this paper we describe the e-Infrastructure that has been developed as part of the nanoCMOS project and outline how it supports large scale high performance computing (HPC) simulations of ensembles of devices which can subsequently be used to model and understand the impact that they have on very large electronic circuits. Key features of this e-Infrastructure include support for very large scale HPC utilization; dealing with federated data sets and associated metadata from multi-level simulations, and addressing challenges related to security and intellectual property protection of data, simulation codes and electronic designs as a whole.
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ItemDevelopment of usable grid services for the biomedical community( 2006)The BRIDGES project was funded by the UK Department of Trade and Industry to directly address the needs of the cardiovascular research scientists investigating the genetic causes of hypertension as part of the Wellcome Trust funded (£4.34M) Cardiovascular Functional Genomics (CFG) project. Specifically, the BRIDGES project developed a compute Grid and a data Grid with security at its heart. This paper presents the experiences in developing usable Grid services for the bio-community and the different phases of prototypes that were refined based upon user requirements and feedback.
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ItemSupporting security-oriented, inter-disciplinary research: crossing the social, clinical and geospatial domains(UK e-Science All Hands Meeting, 2008)
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ItemUser oriented access to secure biomedical resources through the grid(Life Science Grid Conference, 2006)
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ItemTrust realisation in collaborative clinical trials systems(British Computer Society, 2007)
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ItemFormalising dynamic trust negotiations in decentralised collaborative e-health systems(IEEE Computer Society, 2007)Access control in decentralised collaborative systems present huge challenges especially where many autonomous entities including organizations, humans, software agents from different security domains seek to access and share resources in a secure and controlled way. Automated trust negotiation (ATN) is one approach that has been proposed for trust discovery and realisation, which enables entities viz. Strangers to access resources across autonomous boundaries through iterative exchange of credentials. Various negotiation strategies have been proposed to protect credential disclosure during trust negotiations. However in some domains such as e-health, not all entities are willing to negotiate credentials or disclose access policies directly to strangers regardless of negotiation strategies and instead prefer to negotiate and disclose sensitive information only to strangers within what we refer to as a circle of trust. In this paper, we introduce a formal model to describe how locally trusted intermediary parties can provide multiple negotiation and delegations hops to protect credentials and access policies. We propose a dynamic trust negotiations (DTN) model that not only protects sensitive information from disclosure but also reduces semantic issues that exist with credentials in decentralized systems. This work is currently being explored and implemented within the e-health domain: specifically in the MRC-funded Virtual Organisation for Trials of Epidemiological Studies (VOTES) project.
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ItemSecure, performance-oriented data management for nanoCMOS Electronics(IEEE, 2008-12-01)