Biochemistry and Pharmacology - Research Publications

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    Scipion web tools: Easy to use cryo-EM image processing over the web
    Conesa Mingo, P ; Gutierrez, J ; Quintana, A ; de la Rosa Trevin, JM ; Zaldivar-Peraza, A ; Cuenca Alba, J ; Kazemi, M ; Vargas, J ; del Cano, L ; Segura, J ; Sorzano, COS ; Maria Carazo, J (WILEY, 2018-01)
    Macromolecular structural determination by Electron Microscopy under cryogenic conditions is revolutionizing the field of structural biology, interesting a large community of potential users. Still, the path from raw images to density maps is complex, and sophisticated image processing suites are required in this process, often demanding the installation and understanding of different software packages. Here, we present Scipion Web Tools, a web-based set of tools/workflows derived from the Scipion image processing framework, specially tailored to nonexpert users in need of very precise answers at several key stages of the structural elucidation process.
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    Improving 3D reconstructions of macromolecular conformations
    Kazemi, M ; Sorzano, COS ; Georges, AD ; Carazo, JM ; Vargas, J (INT UNION CRYSTALLOGRAPHY, 2018-07)