Anatomy and Neuroscience - Research Publications

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End date: 2019 × Start date: 2016 × Type: Chapter ×

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    Trends and Challenges in Biobanking
    Kaye, J ; Bell, J ; Prictor, M ; Munsie, M ; Freckelton, I ; Petersen, K (Federation Press, 2017)
    The last twenty years have seen the emergence of the phenomena of biobanks, which are now regarded as essential research infrastructure in most countries around the world. However, the very nature of biobanks, as long-term repositories of sample and data that are used for many different research purposes continues to challenge many of the legal requirements for medical research, both in the UK and Australia. This chapter will provide an overview of biobanking and discuss some of the legal challenges that these activities raise by discussing and comparing the UK and Australian legal landscapes.
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    Blindspots and boundaries: Exploring the role and ethical responsibilities of facilitators of stem cell tourism
    MUNSIE, M ; Martin, DE ; Lundin, S ; Krolokke, C ; Muller, E ; Peterson, M (African Sun media, Stellenbosch, 2016)
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    Non-coding RNAs: An Introduction
    Yang, JX ; Rastetter, RH ; Wilhelm, D ; Wilhelm, D ; Bernard, P (SPRINGER, 2016)
    For many years the main role of RNA, it addition to the housekeeping functions of for example tRNAs and rRNAs, was believed to be a messenger between the genes encoded on the DNA and the functional units of the cell, the proteins. This changed drastically with the identification of the first small non-coding RNA, termed microRNA, some 20 years ago. This discovery opened the field of regulatory RNAs with no or little protein-coding potential. Since then many new classes of regulatory non-coding RNAs, including endogenous small interfering RNAs (endo-siRNAs), PIWI-associated RNAs (piRNAs), and long non-coding RNAs, have been identified and we have made amazing progress in elucidating their expression, biogenesis, mechanisms and mode of action, and function in many, if not all, biological processes. In this chapter we provide an introduction about the current knowledge of the main classes of non-coding RNAs, what is know about their biogenesis and mechanism of function.