Sir Peter MacCallum Department of Oncology - Theses

Permanent URI for this collection

http://hdl.handle.net/11343/38322

Filters

2016 1
1
Reset filters

Settings
Statistics
Citations
End date: 2016 × Start date: 2016 × Type: PhD thesis × Subject: ageing ×

Search Results

Now showing 1 - 1 of 1
  • Item
    Thumbnail Image
    Pericytes as microenvironmental regulators of skin tissue regeneration and skin ageing
    Zhuang, Lizhe ( 2016)
    This study focuses on how pericytes can contribute to the epidermal cell microenvironment in human skin, using a 3D organotypic co-culture model, I have shown that in the presence of pericytes, epidermal cells regenerate an epithelium that more closely resemble normal healthy skin with respect to basal cell morphology and various biochemical characteristics. Characterization of pericytes in skin ageing and their functionality in organotypic co-culture model suggests a microenvironmental modulatory role of pericytes in skin ageing and epithelial tissue repair.