Critical Care - Research Publications

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Author: Braitberg, George × Author: Eastwood, Glenn × Author: French, Craig × End date: 2019 × Start date: 2011 × Type: Journal Article ×

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    Can pre-hospital administration reduce time to initial antibiotic therapy in septic patients?
    Cudini, D ; Smith, K ; Bernard, S ; Stephenson, M ; Andrew, E ; Cameron, P ; Lum, M ; Udy, A ; Peake, S ; Delaney, A ; Bellomo, R ; Cameron, PA ; Cooper, DJ ; Cross, A ; Gomersall, C ; Graham, C ; Higgins, AM ; Holdgate, A ; Howe, BD ; Jacobs, I ; Johanson, S ; Jones, P ; Kruger, P ; McArthur, C ; Myburgh, J ; Nichol, A ; Pettila, V ; Rajbhandari, D ; Webb, SAR ; Williams, A ; Williams, J ; Williams, P (WILEY, 2019-08)
    OBJECTIVE: To quantify the potential time saved with pre-hospital antibiotic therapy in sepsis. METHODS: Study data for adult patients transported by Ambulance Victoria (AV), and enrolled into the Australasian Resuscitation In Sepsis Evaluation (ARISE), were linked with pre-hospital electronic records. RESULTS: An AV record was identified for 240 of 341 ARISE patients. The pre-hospital case notes referred to potential infection in 165 patients. The median time to first antibiotic administration from loading the patient into the ambulance was 107 (74-160) min. CONCLUSIONS: ARISE patients in Victoria were frequently identified pre-hospital. An opportunity exists to study the feasibility of pre-hospital antibiotic therapy.