Graeme Clark Collection

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    The development of speech perception in children using cochlear implants: effects of etiologic factors and delayed milestones
    PYMAN, BRIAN ; Blamey, Peter J. ; Lacy, Peter ; Clark, Graeme M. ; DOWELL, RICHARD ( 2000)
    Hypothesis: Speech perception outcomes for cochlear implantation of children vary over a wide range, and it is hypothesized that central pathologic states associated with certain causes of hearing impairment account for a substantial part of the variance. Study Design: A retrospective analysis was carried out to ascertain the relationships between speech perception, etiologic factors, and central pathologic states as indicated by preoperative delayed motor milestones and/or cognitive delays. Setting: Data were obtained from the pre-and postoperative records of patients attending a hospital cochlear implant clinic. Patients: Results for 75 consecutive patients up to age 5 years who underwent implantation were included in the study. Intervention: Patients received a 22-electrode cochlear prosthesis and were seen by the clinic for regular tune-up and assessments. Home-and school-based habilitation was recommended by the clinic. Main Outcome Measures: Speech perception measures were classified on a five-point scale to allow for different evaluation procedures at different ages and developmental stages. Results: The incidence of motor and cognitive delays were fairly evenly spread across etiologic factors, except for cytomegalovirus, which had a much higher than average incidence. Children with motor and/or cognitive delays were significantly slower than other children in the development of speech perception skills after implantation. Etiologic factors did not have a statistically significant effect on speech perception outcome. Conclusions: It is likely that central pathologic states account for a substantial part of the variance among children using cochlear implants. Specific indicators of central pathologic states should be used to assess a child's prognosis in preference to less specific information based on etiologic factors alone.
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    Habilitation issues in the management of children using the cochlear multiple-channel cochlear prosthesis
    Cowan, Robert S. C. ; Barker, Elizabeth J. ; Dettman, Shani J. ; Blamey, Peter J. ; RANCE, GARY ; Sarant, Julia Z. ; Galvin, Karyn L. ; Dawson, Pam W. ; Hollow, Rod ; Dowell, Richard C. ; PYMAN, BRIAN ; Clark, Graeme M. (Wien, 1994)
    Since 1985, a significant proportion of patients seen in the Melbourne cochlear implant clinic have been children. The children represent a diverse population, with both congenital and acquired hearing-impairments, a wide-range of hearing levels pre-implant, and an age range from 2 years to 18 years. The habilitation programme developed for the overall group must be flexible enough to be tailored to the individual needs of each child, and to adapt to the changing needs of children as they progress. Long-term data shows that children are continuing to show improvements after 5-7 years of device use, particularly in their perception of open-set words and sentences. Habilitation programs must therefore be geared to the long-term needs of children and their families. Both speech perception and speech production need to be addressed in the specific content of the habilitation program for any individual child. In addition, for young children, the benefits of improved speech perception should have an impact on development of speech and language, and the focus of the programme for this age child will reflect this difference in emphasis. Specific materials and approaches will vary for very young children, school-age and teenage children. In addition, educational setting will have a bearing on the integration of listening and device use into the classroom environment.
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    The University of Melbourne/Nucleus cochlear prosthesis
    Clark, Graeme M. ; Blamey, P. J. ; Brown, A. M. ; Busby, P. A. ; Dowell, R. C. ; Franz, B. K-H. ; Millar, J. B. ; Pyman, B. C. ; Shepherd, R. K. ; Tong, Y. C. ; Webb, R. L. ; Brimacombe, J. A. ; Hirshorn, M. S. ; Kuzma, J. ; Mecklenburg, D. J. ; Money, D. K. ; Patrick, J. F. ; Seligman, P. M. ( 1988)
    This is a review of research to develop the University of Melbourne/Nucleus cochlear prosthesis for patients with a profound-total hearing loss. A more complete review can be obtained in Clark et al. A prototype receiver-stimulator and multiple-electrode array developed at the University of Melbourne was first implanted in a postlingually deaf adult patient with a profound-total hearing loss on 1 August 1978. A speech processing strategy which could help this patient understand running speech, especially when combined with lipreading was developed in 1978 following initial psychophysical studies. A prototype wearable speech processor was fabricated in 1979, that could provide significant help for the first two patients in understanding running speech when used in combination with lipreading compared with lipreading alone, and it also enabled them to understand some running speech when using electrical stimulation alone. An implantable receiver-stimulator and wearable speech processor embodying the principles of the prototype devices were then produced for clinical trial by the Australian biomedical firm, Nucleus Ltd, and its subsidiaries, Cochlear Pty Ltd and Cochlear Corporation. This cochlear implant was initially clinically trialled on six patients at The Royal Victorian Eye & Ear Hospital in 1982, and shown to give similar results to those obtained with the prototype device. In view of these findings a clinical trial was carried out for a Premarket Approval Application to the US Food and Drug Administration (FDA), and extended to a number of centres in the US, Canada, and West Germany. This clinical trial confirmed that patients could understand running speech when electrical stimulation was combined with lipreading, and that some patients could also understand running speech when using electrical stimulation alone. Today, more than 600 patients world-wide are using cochlear implants developed from the research described in this paper.