Graeme Clark Collection

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    The role phase-contrast imagining in intra-cochlear electrode development
    Wilkins, S. ; Saudners, E. ; Clark, Graeme M. ; Cowan, R. ; XU, JIN ; Stevenson, A. W. ; Gao, D. ; Tykocinski, M. ; Cohen, L. ; Dahm, Markus ( 2000)
    In order to improve the design of intracochlear multichannel electrode arrays, it is fundamental that we have knowledge of the exact anatomical , position of the electrode within the scala of the cochlea. Currently, conventional skull radiography is still the mainstay of post-operative radiological assessment of electrode positioning. The present work investigates the use of phase-contrast radiography, a new x-ray modality, to provide improved imaging of the inner ear and the intracochlear electrode array in the human temporal bone (TB).
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    Safety studies and preliminary patient trails with a new perimodiolar electrode array
    Clark, Graeme M. ; COWAN, ROBERT ; Saunders, Elaine ; TYKOCINSKI, MICHAEL ; COHEN, LAWRENCE ; Treaba, Claudiu ; BRIGGS, ROBERT ; Dahm, Markus ( 2000)
    A new perimodiolar electrode array, the curly-with stylet (CwS), has been developed and undergone safety trials in human cadaver temporal bones. The array was developed as a result of animal and modelling studies which indicated that there are potential advantages in situating the electrode array in closer proximity to the neural elements. Preliminary studies with four patients in Melbourne implanted with a developmental pre-curved array had supported the predictions of lower current requirements and possibly more focussed spread of excitation.
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    Where to now? - Impact of New Technologies on use of cochlear implants
    Van Hoesel, R. ; Zhang, A. ; Tykocinski, M. ; Dham, M. ; Patrick, J. ; Parker, J. ; Clark, Graeme M. ; Cowan, R. S. C. ; Saunders, E. ; Vandali, A. E. ; Dowell, R. C. ; Treaba, C. ; Harrison, J. M. ( 2000)
    The history of cochlear implant use by adults and children with profound hearing loss although relatively short (20 some years), has been characterised by continual technological innovations which have enhanced the performance, packaging, and clinical use of these devices. In particular, the development of the Nucleus multiple channel cochlear implant has included a series of speech processing hardware and speech processing strategy, implemented by Cochlear Limited, and based on research findings that have resulted in an increase in mean speech perception benefits for adults and children.
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    Development of safe and effective electrodes: a risk management approach [Abstract]
    Clark, Graeme M. ; COWAN, ROBERT ; Saunders, Elaine ; TYKOCINSKI, MICHAEL ; Cohen, Lawrence ; Treaba, Claudiu ; Briggs, Robert S. ; GIBSON, PETER ( 1999)
    Results from studies on experimental animals, computer modelling and preliminary psychophysical studies with three patients, have confirmed the potential for subjective improvement with electrode arrays which lie closer to the modiolus than does the Nucleus straight array. Results of psychophysical studies with three cochlear implant patients, using developmental pre-curved arrays, confirm the feasibility of improving patients' performance through improvements in electrode design. In particular, it was found in psychophysical tests, with patients using a developmental pre-curved electrode array, that both maximum comfortable level and threshold reduced with decreasing distance of a stimulated electrode from the modiolus, and that the dynamic range increased. More intense neural excitation patterns were obtained with the closer electrodes. From this it is inferred that the development of more sophisticated electrode arrays, positioned closer to the modiolus than is currently the case with the Nucleus standard array, will enable the development of improved speech processing strategies. There are technical constraints in the design of a peri-modiolar array, and currently a number of approaches to this problem have been investigated. Whilst the goal of the design is that it be effective for sophisticated and variable manners of stimulus delivery, a primary constraint is safety.
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    Insertion study using new peri-modiolar electrode array designs [Abstract]
    Treaba, Claudiu ; Clark, Graeme M. ; Cowan, Robert S. ; Tykocinski, Michael J. ; Cohen, Lawrence T. ; Saunders, Elaine ; Pyman, Brian C. ; Briggs, Robert S. ; Dahm, Markus C. ( 1999)
    Intracochlear multi-channel cochlear implants have been shown to successfully provide auditory information for profoundly deaf patients by electrically stimulating discrete populations of auditory nerve fibers via a scala tympani (ST) electrode array. Histological and radiological examination of implanted human temporal bones showed that the current straight Nucleus® array is usually positioned against the outer wall of the ST. An electrode array close to the modiolus could be expected to reduce stimulation thresholds and result in a more localized neural excitation pattern.