Graeme Clark Collection

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http://hdl.handle.net/11343/375

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Author: Clark, Graeme × Author: Shepherd, Robert × End date: 1997 × Start date: 1997 × Type: Conference Paper ×

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    Peri-modiolar electrode arrays: a comparison of electrode position n the human temporal bone
    Shepherd, R. K. ; Treaba, C. G. ; Cohen, L. ; Pyman, B. ; Huigen, J. ; Xu, J. ; Clark, Graeme M. (Monduzzi Editore, 1997)
    This paper describes a radiologic evaluation of three types of peri-modiolar arrays, comparing their trajectory within the scala tympani with a standard Mini-22 electrode. All peri-modiolar arrays were found to lie closer to the modiolus for much of their insertion length compared with the standard array. While one design showed evidence for the potential of increased insertion trauma, two designs produced satisfactory results. Although further electrode development, temporal bone and histopathologic studies arE required, it would appear that the benefits of peri-modiolar electrode arrays will be realised clinically.
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    The interactions between the cytokine LIF and the neurotrophins on spiral ganglion cells
    Marzella, P. L. ; Clark, Graeme M. ; Shepherd, R. K. ; Bartlett, P. F. ; Kilpatrick, T. J. (Monduzzi Editore, 1997)
    The survival of auditory neurones depends on the continued supply of trophic factors. Early post-natal spiral ganglion cells (SGC) in a dissociated cell culture were used as a model of auditory innervation to test the trophic factors leukaemia inhibitory factor (LIF) and neurotrophin-3 (NT-3) for their ability, individually or in combination, to promote neuronal survival.