Graeme Clark Collection

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http://hdl.handle.net/11343/375

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Author: Clark, Graeme × Author: Xu, Jin × End date: 2001 × Type: Conference Paper ×

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    Phase-contrast radiography: a new x-ray technique for cochlear implant research
    XU, JIN ; Stevenson, A. W. ; Gao, D. ; Dahm, M. ; Wilkins, S. W. ; Clark, Graeme M. (Moduzzi Editore, 2000)
    This study examines the application of a new x-ray modality, phase contrast radiography, in temporal bone (TB) imaging. Preliminary results from TB samples have shown that phase-contrast imaging offers greater contrast for edge-type features and weakly absorbing soft-tissue resulting in improved visualization of anatomic details of inner ear and microelectrode structures. This is potentially valuable in the development of new electrode arrays for cochlear implants.
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    Intracochlear damage following insertion of the Nucleus 22 standard electrode array: a post mortem study of 14 implant patients
    Dahm, M. C. ; XU, JIN ; Tykocinski, Michael. ; Clark, Graeme M. ( 2000)
    The insertion of an intracochlear electrode array may cause trauma to cochlear structures which can result in degeneration of neural elements, jeopardizing the potential benefits of electrical stimulation. Safety studies for the assessment of trauma associated with the Nucleus 22 standard electrode array involved animal experiments as well as insertion studies in post mortem temporal bones. However, there are only few histological studies of temporal bones from deceased cochlear implant patients. A review of our temporal bone collection of implantees originating from a variety of centres has been conducted to evaluate the effects of electrode insertion trauma associated with the Nucleus 22 standard array.
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    Peri-modiolar electrode arrays: a comparison of electrode position n the human temporal bone
    Shepherd, R. K. ; Treaba, C. G. ; Cohen, L. ; Pyman, B. ; Huigen, J. ; Xu, J. ; Clark, Graeme M. (Monduzzi Editore, 1997)
    This paper describes a radiologic evaluation of three types of peri-modiolar arrays, comparing their trajectory within the scala tympani with a standard Mini-22 electrode. All peri-modiolar arrays were found to lie closer to the modiolus for much of their insertion length compared with the standard array. While one design showed evidence for the potential of increased insertion trauma, two designs produced satisfactory results. Although further electrode development, temporal bone and histopathologic studies arE required, it would appear that the benefits of peri-modiolar electrode arrays will be realised clinically.