Graeme Clark Collection

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http://hdl.handle.net/11343/375

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1995 - 1996 2
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Author: Clark, Graeme × Type: Conference Item × Subject: auditory nerve × Subject: cochlear implant × Subject: cochlear%20implant × Subject: electrical stimulation ×

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Now showing 1 - 2 of 2
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    Effects of chronic electrical stimulation on cochlear nuclear neuron size in deaf kittens [Abstract]
    Kawano, Atsushi ; Seldon, H. Lee ; Clark, Graeme M. ; Kakuhisa, Eiji ; Funasaka, Sotaro ( 1996)
    It is now well recognized that normal afferent innervation is necessary for the development. This study investigated the effect of chronic electrical stimulation of the auditory nerve on the maturation of cochlear nucleus soma area of the neonatally deafened kittens. Eight kittens were deafened using kanamycin and ethacrynic acid, received a stimulated intracochlear implant in the left side and a dummy implant in right side, and classified two groups - the stimulated and the control group.
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    Decrement in auditory nerve function following acute high rate stimulation in guinea pigs [Abstract]
    Tykocinski, M. ; Shepherd, R. K. ; Clark, Graeme M. ( 1995)
    Cochlear implants have been shown to successfully provide profoundly deaf patients with auditory cues for speech discrimination. Psychophysical studies suggested that speech processing strategies based on stimulus rates of up to 1000 pulses per second (pps) may lead to an improvement in speech perception, due to a better representation of the rapid variations in the amplitude of speech. However, "neural fatigue" has been known to occur following brief periods of electrical stimulation at rates high enough to ensure that stimuli occur within the neurons relative refractory period, and has been shown to depend on stimulus duration and rate of the evoked neural activity. Prolonged electrical stimulation at these high stimulus rates could, therefore, have an adverse effect on the neurons metabolism and result in cellular energy depletion.