Graeme Clark Collection

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    Pitch comparisons of acoustically and electrically evoked auditory sensations
    Blamey, Peter J. ; Dooley, Gary J. ; Parisi, Elvira S. ; Clark, Graeme M. ( 1996)
    Cochlear implant users with some residual hearing in the non-implanted ear compared the pitch sensations produced by acoustic pure tones and pulsatile electric stimuli. Pitch comparisons were obtained for pure tones and electrical stimuli presented at different positions (electrodes) in the scala tympani, keeping the electric pulse rate fixed at 100, 250, or 800 pps. Similarly, pitch comparisons were obtained for electrical stimuli with variable pulse rates presented to two fixed electrode positions (apical and basal) in the cochlea. Both electrode position and pulse rate influenced the perceived pitch of the electrical signal and 'matched' electric and acoustic signals were found over a wide range of frequencies. There was a large variation between listeners. For some stimuli, listeners had difficulty in deciding whether the acoustic or electric stimulus was higher in pitch. Despite the variability, consistent trends were obtained from the data: higher frequencies tended to be matched by more basal electrodes for all pulse rates. Higher frequencies tended to be matched by higher pulse rates for both electrode positions. The electrode positions that 'matched' pure tones were more basal than predicted from the characteristic frequency coordinates of the basilar membrane in a normal human cochlea.
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    Speech perception using a two-formant 22-electrode cochlear prosthesis in quiet and in noise
    Dowell, Richard C. ; Seligman, Peter M. ; Blamey, Peter J. ; Clark, Graeme M. ( 1987)
    A new speech-processing strategy has been developed for the Cochlear Pty. Ltd. 22-electrode cochlear prosthesis which codes an estimate of the first formant frequency in addition to the amplitude. voice pitch and second formant frequencies. Two groups of cochlear implant patients were tested 3 months after implant surgery, one group (n= 13) having used the old (F0F2) processing strategy and the other (n=9) having used the new (F0FIF2) strategy. All patients underwent similar postoperative training programs. Results indicated significantly improved speech recognition for the F0FIF2 group particularly on open set tests with audition alone. Additional testing with a smaller group of patients was carried out with competing noise (speech babble). Results for a closed set spondee test showed that patient performance was significantly degraded at a signal-to-noise ratio of 10 dB when using the F0F2 strategy, but was not significantly affected with the F0FIF2 strategy.
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    Results of a preliminary clinical trial on a multiple channel cochlear prosthesis
    Dowell, R. C. ; Martin, L. F. A. ; Clark, Graeme M. ; Brown, A. M. ( 1985)
    Speech discrimination testing was carried out under clinical trial conditions for eight profoundly postlingually deaf adults to assess the efficacy of a newly developed 22-channel cochlear prosthesis and speech processor. Three months postoperatively, these patients showed significantly better results with the cochlear prosthesis than for preoperative testing with a conventional hearing aid or vibrotactile aid (following a 6-month trial with the aid) on each of a series of tests from the Minimal Auditory Capabilities battery. Assessment of lipreading enhancement using standard speech tests, consonant recognition studies, and speech tracking showed significant improvements for each patient when using the cochlear prosthesis. Six patients showed a significant amount of open set speech discrimination without lipreading at levels which have not been reported for single electrode cochlear prostheses. The two patients who performed poorly on these tests both had restricted multiple channel systems due to their disease, one patient being restricted to virtually a single channel system and the other to only ten of the 22 electrodes. These results indicate that this multiple channel cochlear prosthesis has potential as a treatment for profound postlingual deafness over a wide range of etiologies and ages.
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    Clinical results using a multiple-channel cochlear prosthesis
    Dowell, R. C. ; Webb, R. L. ; Clark, Graeme M. ( 1984)
    A total of eight profoundly deaf patients have been implanted with the Nucleus Limited multiple-channel cochlear prosthesis at the University of Melbourne since it became available in late 1982. All patients are everyday users of the device. Speech testing using the device alone has shown consistently high scores for a variety of closed set tests and significant levels of open set speech understanding in most of the patients. Lipreading assessment with phoneme, word, sentence and speech tracking material shows significant improvement when using the prosthesis for all patients tested. Other benefits reported are recognition of environmental sounds, decrease in tinnitus. increased confidence in social and vocational situations and improved voice control. One patient is able to cope with interactive conversations over the telephone and three others are able to use the telephone in a limited way without special codes.
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    A multi-channel hearing prosthesis for profound-to-total hearing loss
    Money, D. K. ; Clark, Graeme M. ; Tong, Y. C. ; Patrick, J. F. ; Seligman, P. M. ; Crosby, P. A. ; Kuzma, J. A. ( 1984)
    A multi-channel cochlear implant hearing prosthesis providing 22 separate channels of stimulation has been developed. The electronics for the implantable receiver-stimulator have been incorporated on a single chip, using digital circuits and employing CMOS technology. The chip is enclosed in a titanium capsule with platinum/ceramic electrode feed-throughs. A pocket-sized speech processor and directional microphone extract the following speech parameters: signal amplitude, fundamental frequency and formant frequency. The fundamental frequency is coded as electric pulse rate, and formant frequency by electrode position. The speech processor has been realized using hybrid circuits and CMOS gate arrays. The multi-channel prosthesis has undergone a clinical trial on four postlingually deaf patients with profound-total hearing losses. The speech perception results indicate that they were able to obtain open-set speech recognition scores for phonetically balanced words, CID sentences and spondees. In all cases the tests showed significant improvements when using the cochlear prosthesis combined with lipreading compared to lipreading alone.
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    A multi-channel cochlear prosthesis for profound-to-total hearing loss
    Money, D. K. ; Clark, Graeme M. ; Tong, Y. C. ; Patrick, J. F. ; Seligman, P. M. ; Crosby, P. A. ; Kuzma, J. A. ( 1984)
    A multi-channel cochlear prosthesis for profound-total hearing loss has been developed by the University of Melbourne and Nucleus Limited. Clinical trials have shown that the prosthesis provides significant help for postlingually deaf adult patients (lost hearing after normal language patterns have been established). The prosthesis helps the patients understand running speech when combined with lipreading, and a proportion obtain significant open-set speech scores for electrical stimulation alone. The patients with these open-set score can use the device in situations where lipreading is not possible, for example, to converse over the telephone. The prosthesis consists of an externally worn, pocket-sized speech-processor, a headset and an implanted receiver/stimulator and electrode array. The headset contains an .ear-level directional microphone that picks up the speech signal. The speech processor encodes the speech as a series of electrical pulses on the electrode array. The data describing these pulses and the power required to produce them, are sent to the receiver/stimulator from .a radio-frequency coil mounted on the headset. The receiver/stimulator decodes the data and delivers the speech signal as a series of biphasic electrical pulses to the 22 electrodes which have been gently passed along the scala tympani during implantation.
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    Cochlear implant round window sealing procedures in the cat: an investigation of autograft and heterograft materials
    Clark, Graeme M. ; Shepherd, R. K. ( 1984)
    In this series of experiments it was shown that a round window seal produced with a muscle autograft or a Teflon felt disc glued to the electrode prevented a Staphylococcus aureus infection in the bulla extending to the cochlea. The seal following a fascial autograft also prevented β-haemolytic streptococci type A spreading to the basal turn of the cochlea. On the other hand Dacron® velour is contra-indicated as it was associated with a strong inflammatory response and a high incidence of infection. The studies also indicated that infection can extend to the cochlea before the round window membrane has healed. The junctional area between the graft and the margin of the round window niche is a potentially vulnerable site.
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    Clinical trial of a multi-channel cochlear prosthesis: results on 10 postlingually deaf patients
    Clark, Graeme M. ; Dowell, R. C. ; Pyman, B. C. ; Brown, A. M. ; Webb, R. L. ; Tong, Y. C. ; Bailey, Q. ; Seligman, P. M. ( 1984)
    The clinical trial of a multi-channel cochlear prosthesis has been carried out on 10 profoundly-totally deaf adult patients. Speech perception tests have shown that all the patients received significant benefit from the device. They obtained improvements in understanding running speech from 47% to 550% when using the device in conjunction with lipreading compared to lipreading alone. With an open-set CID sentence test, three patients obtained scores showing an ability to understand speech without the need to lipread, and a further three patients had scores indicating they could also receive useful information without lipreading. In two patients, very limited open-set scores for electrical stimulation alone were obtained. This was most probably due to the fact that only a few channels of stimulation were possible due to cochlear disease and they were therefore receiving information more like a single-channel device. The prosthesis has also been found to provide considerable help in hearing and recognizing everyday sounds.