Graeme Clark Collection

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    Speech perception & indirect benefits for severely hearing impaired children using cochlear implants [Abstract]
    Cowan, Robert S. C. ; Dowell, Richard C. ; Nott, P. ; Rennie, Maree ; Pyman, B. ; Clark, Graeme M. ( 1998)
    The benefits to speech perception, speech production, communication, and quality of life were investigated for severely hearing impaired children using cochlear implants and hearing aids. For the youngest children, assessments of psychological status, and use of a battery of cognitive and language tests were important factors in determining performance benefits prior to the child developing speech. For older children, the effects of increased one-to-one oral habilitation, and systematic encouragement of parental involvement were also investigated. Results suggested that parental support for consistent device use was an important factor in producing outcomes. Children with residual hearing were more likely to achieve open-set perception. Each child was also assessed for changes in quality of life, through use of a standardized health utility instrument. Results from the group were collated, and teamed with a costing assessment for the procedure, which allowed a complete cost-utility analysis to be completed. Results suggested that indirect benefits, such as the effects on speech production, usual activities, lower concentration, and less distress were ranked as more important than changes to hearing in a number of the children. Costs per QALY were consistent with those reported in the literature, and suggested that the cochlear implant is highly cost-effective as a medical technology.
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    Performance benefits and costs for children using cochlear implants and hearing aids [Abstract]
    Barker, Elizabeth ; Wright, Maree ; Godwin, Genevieve ; Hollow, Rod ; Rehn, Chris ; Gibson, William P.R. ; Clark, Graeme M. ; Cowan, Robert S. C. ; Dowell, Richard C. ; King, Alison ; Rennie, Maree ; Dettman, Shani J. ; Everingham, Colleen ( 1998)
    The value of cochlear implants as an established clinical option for profoundly hearing impaired adults and children has been supported by significant research results over a number of years which has clearly established the benefits available (U.S. National Institutes of Health Consensus Statement 1995). Benefit has traditionally been considered as the direct impact of the cochlear implant procedure on speech perception, or in the case of children, on the use of that auditory information to develop understandable speech and to acquire a knowledge of language. As a consequence of continuing research to improve hardware and speech processing strategies, mean scores on open-set tests of monosyllables or sentence materials for implanted adults using the cochlear implant alone without lipreading have continued to show an upwards trend. In response to the increased mean scores in quiet, perception tests in background noise are now being used as a more accurate direct measure of the potential benefits of cochlear implants to severely-to-profoundly hearing-impaired candidates. Consideration should also be given to indirect benefits, such as reduction in the stress of listening and lipreading, improved performance at work, enhanced opportunity to maintain speech, or in children to develop speech which is understandable to the general community, and the social effects of reducing the isolating effects of profound deafness. Measurement of indirect benefit can be combined with an analysis of the costs of the procedure, enabling evaluation of the implant procedure from a cost-utility standpoint, and a comparison of outcomes using other technologies such as hearing aids. This study will present data on direct and indirect benefits for hearing-impaired children using Nucleus cochlear implant systems, and compare this data with benefits shown for similarly hearing impaired children using hearing aids. The significance of these results to cost-effective delivery of services will be discussed.
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    Evaluation of direct and indirect benefits in the selection of cochlear implant candidates [Abstract]
    Cowan, Robert S. C. ; Dowell, Richard C. ; Hollow, Rod ; Dettman, Shani J. ; Clark, Graeme M. ( 1998)
    The value of cochlear implants as an established clinical option for profoundly hearing-impaired adults and children has been supported by significant research results over a number of years which clearly established the benefits available (U.S. National Institutes of Health Consensus Statement 1995). Benefit has traditionally been considered as the impact of the cochlear implant procedure on hearing, and in the case of children, on the use of that hearing to develop speech and language. However, as a result of continuing research, improvements have been realised both in hardware and speech processing. As a direct consequence of these improvements, the mean open-set implant-alone speech perception scores for implanted adults have continued to increase. In response to the increased mean scores shown by adult cochlear implant users in quiet, perception tests in background noise are now being used as a direct measure of the potential benefits of cochlear implants available to severely-to-profoundly hearing-impaired candidates. In addition, consideration in candidature should also be given to indirect benefits, such as reduction in the stress. of listening and lipreading, improved performance at work, enhanced opportunity to maintain or in children to develop speech which is understandable to the general community, and the social effects of reducing the isolating effects of profound deafness. Measurement of indirect benefit can be combined with a costing study, enabling evaluation of the implant procedure from a cost-utility standpoint, and comparison of outcomes using other technologies such as hearing aids. The use of new approaches to candidature, including new measures of direct and indirect benefit is reported using data from the Melbourne cochlear implant program.
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    The auditory cortex and auditory deprivation: experience with cochlear implants in the congenitally deaf [Abstract]
    Shepherd, R. K. ; Hartmann, R. ; Heid, S. ; Klinke, R. ; Blamey, P. J. ; Dowell, R. C. ; Clarke, Graeme M. ( 1995)
    The primary auditory cortex (AI) exhibits a topographic representation of the organ of Corti in normal hearing animals. Plasticity studies have shown that this orderly representation of frequency can be modified following a restricted hearing loss or by behavioural trainingl,2. Little is known, however, of the effects of a profound hearing loss on AI, although a number of early studies have suggested an enhancement of activity from other modalities3. Knowledge of the functional status of the central auditory pathway in the profoundly deaf, and the ability of these structures to undergo reorganization particularly following long periods of auditory deprivation - are important issues for the clinical management of cochlear implant patients. In this paper we review our recent clinical and experimental experience with cochlear implants in the congenitally deaf.
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    Results of multichannel cochlear implantation in very young children [Abstract]
    Galvin, K. ; Clark, Graeme M. ; DETTMAN, SHANI ; Dowell, Richard C. ; Barker, E. J. ; Rance, G. ; Hollow, R. ; Cowan, R. ( 1995)
    Most researchers and clinicians working in the cochlear implant field have assumed that profoundly deaf children will have a better prognosis in terms of speech perception, speech production and language development, implanted at as young an age as possible. However, it has been difficult to gather direct evidence for this hypothesis due to the problems in assessing children under the age of five years with formal tests.
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    Speech perception results for implanted children with different levels of preoperative residual hearing [Abstract]
    Galvin, K.L. ; Rance, G. ; Larratt, M. ; Hollow, R. ; Herridge, S. ; Skok, M. ; Dowell, R.C. ; Pyman, B. ; Gibson, W.P.R. ; Clark, Graeme M. ; Cowan, R. S. C. ; DelDot, J. ; Barker, E. J. ; Sarant, J. Z. ; Dettman, S. ; Pegg, P. ( 1996)
    Many reports have established that hearing-impaired children using the Nucleus 22-channel cochlear implant may show both significant benefits to lipreading, and significant scores on open-set words and sentences using electrical stimulation only. These findings have raised suggestions that severely or severely-to-profoundly deaf children might benefit more from a cochlear implant than conventional amplification.
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    Speech perception results for the nucleus multiple channel cochlear implant in children and adults with residual hearing [Abstract]
    Brimacombe, J.A. ; Arndt, P.L. ; Menapace, C.M. ; Clark, Graeme M. ; Cowan, R. S. C. ; Dowell, R. C. ; Shaw, S. ; Gibson, W. P. R. ; Staller, S. ( 1996)
    Speech perception results for profoundly deaf children and adults using advanced speech processing strategies for the Nucleus multiple-channel cochlear implant have continued to improve, and are now better than those reported in research with severely-to-profoundly hearing-impaired people using aided residual hearing.
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    Speech perception benefits for implanted children with preoperative residual hearing [Abstract]
    Hollow, R. ; Rance, G. ; Dowell, R.C. ; Pyman, B. ; Clark, Graeme M. ; Cowan, R. S. C. ; Galvin, K. L. ; Barker, E. J. ; Sarant, J. Z. ; Dettman, S. ( 1995)
    Since the implantation of the first children with the Nucleus 22-channel cochlear prosthesis in Melbourne in 1985, there has been rapid expansion in the number of implanted children world-wide. Improved surgical technique and experience in paediatric assessment and management have contributed to a trend to implant very young children. At the same time there has also been continuing development of improved speech processing strategies resulting in greater speech perception benefits.
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    Multichannel cochlear implants in children: an overview of experimental and clinical results [Abstract]
    Shepherd, Robert K. ; Dowell, Richard C. ; Xu, Shi-Ang ; Clark, Graeme M. ; McDermott, Hugh J. ; McKay, Colette M. ( 1991)
    During the last decade there has been great progress in the clinical management of profound, postlinguistically deafened adults through the use of multichannel cochlear implants. The device developed by Cochlear Pty. Ltd. in association with the University of Melbourne, electrically stimulates selective regions of the residual auditory nerve using an array of 22 Pt electrodes located within the scala tympani. A speech processing strategy has been developed to provide patients with both voice pitch, and first and second formant information. Following experimental safety studies and successful clinical trials, this device was approved for use in adults by the United States FDA in 1985. In 1990, following further miniaturization of the implant, the FDA approved the device for use in profoundly deafened children above the age of two years. The present paper presents an overview of our recent biological safety studies and clinical experience with cochlear implants in children, and discusses the likely future development of these devices. Our biological safety studies were designed to evaluate the safety and design requirements of cochlear implantation in children, and more recently has focussed on issues for implantation in very young children (< 2 years old). These studies included the measurement of growth in the human temporal bone and the development of lead wires that can accommodate such growth, the development of an electrode fixation technique close to the cochlea, the effect of cochlear implantation on skull growth, the effect of long-term electrical stimulation on the maturing auditory system and the stimulating electrodes, and the effect of middle ear infection on cochlear implantation. Our clinical experience is based on twenty-five children that have now been implanted in our clinic. They include (i) postlinguistically deafened children; (ii) congenitally or early-deafened young children; and (iii) congenitally or early deafened adolescents. Clinical testing has shown improvements in speech perception, speech production and language in all three groups. Postlinguistically deafened children show similar speech perception results to postlinguistically deafened adults. For the congenitally deaf, younger children tend to show better results than the adolescents. Significantly, these clinical results are consistent with results from 142 children obtained from clinics throughout the world. These experimental and clinical results support the use of cochlear implants in young children. Further clinical improvements can be expected in the future with advances in both hardware and speech processing strategies.