Graeme Clark Collection

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Author: Franz, Burkhard × Author: Shepherd, Robert × End date: 1989 × Start date: 1987 × Type: Journal Article × Subject: Streptococcus pyogenes × Subject: ear infection × Subject: otology ×

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    Middle ear infection postimplantation: response of the round window membrane to Streptococcus pyogenes
    Cranswick, N. E. ; Franz, B. K-H. ; Clark, Graeme M. ; Shepherd, R. K. ; Bloom, D. M. ( 1987)
    The seal of the implanted round window membrane to resist Streptococcus pyogenes invasion from the middle ear was investigated in 12 cats. Results showed that the implanted round window membrane is able to form a barrier for S pyogenes starting 1 week postimplantation. Under normal conditions S pyogenes did not pass through the round window membrane, nor through the gap that existed between the membrane and the prosthesis. Mechanical disruption of the round window seal, however, and severe inflammatory response to S pyogenes caused the infection to extend into the inner ear.