Graeme Clark Collection

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Author: Franz, Burkhard × End date: 1999 × Start date: 1990 × Type: Conference Item × Subject: cochlear implant × Subject: paediatric otology × Subject: safety studies ×

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    Paediatric cochlear implantation: radiological and histopathological studies of skull growth in the monkey
    Shepherd, R. K. ; XU, JIN ; Burton, Martin J. ; Xu, Shi-Ang ; Seldon, H. Lee ; Franz, Burkhard K-H. G. ; Clark, Graeme, M. ( 1993)
    The human skull undergoes significant growth within the first two years of life (Dahm et aI, 1992). Therefore, before children under two can be considered candidates for cochlear implantation, the effects of the surgical procedure on subsequent skull growth must be well understood. To evaluate the effects of implantation on skull growth four macaque monkeys were implanted with dummy cochlear implants at six months of age. To model the procedure in the very young child, the bed for the receiver-stimulator was drilled across a calvarial suture down to the underlying dura and an electrode array inserted into the scala tympani via a mastoidectomy and posterior,tympanotomy. Plain skull radiographs were perioqical1y taken to monitor skull growth for periods of up to three years following implantation. Their longitudinal measurements revealed no evidence of asymmetrical skull growth when compared with unimplanted control animals. Computer tomographic scans taken at post-mortem confirmed these findings. Finally, subsequent histopathological evaluation of the receiver-stimulator package bed indicated that it becomes obliterated by hard tissue, resulting in a localized flattening of the vault under the receiver-stimulator. However, this tissue exhibited histological evidence of sutures, indicating that the surgical procedure should not lead to premature sutural closure. In conclusion, the present experimental results suggest that long-term cochlear implantation in very young children will not lead to any significant skull deformity.