Graeme Clark Collection

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    The interactions between the cytokine LIF and the neurotrophins on spiral ganglion cells
    Marzella, P. L. ; Clark, Graeme M. ; Shepherd, R. K. ; Bartlett, P. F. ; Kilpatrick, T. J. (Monduzzi Editore, 1997)
    The survival of auditory neurones depends on the continued supply of trophic factors. Early post-natal spiral ganglion cells (SGC) in a dissociated cell culture were used as a model of auditory innervation to test the trophic factors leukaemia inhibitory factor (LIF) and neurotrophin-3 (NT-3) for their ability, individually or in combination, to promote neuronal survival.