Graeme Clark Collection

Permanent URI for this collection

http://hdl.handle.net/11343/375

Filters

1995 - 1997 4
4
Reset filters

Settings
Statistics
Citations
Author: Paolini, Antonio × End date: 1998 × Start date: 1990 × Type: Conference Paper × Subject: otolaryngology ×

Search Results

Now showing 1 - 4 of 4
  • Item
    Thumbnail Image
    The effect of pulsatile intracochlear electrical stimulation on intracellularly recorded cochlear nucleus neurons
    Paolini, Antonio, G. ; Clark, Graeme M. (Monduzzi Editore, 1997)
    The anterior division of the ventral cochlear nucleus (AVCN) is the first relay station of the auditory pathway. We examined responses of neurons in the A VCN to intracochlear electrical stimulation using in vivo intracellular recordings. Twin pulse stimulation results indicated that these neurones evoke action potentials which are able to follow pulsatile stimulation at high rates. This ability to respond to each pulse along the stimulus train diminished when stimulus duration was increased to 50 ms. At rates 400 Hz and below in all neurones tested a deterministic response was seen to this longer duration pulsatile stimulation. With increasing rate of stimulation the response become more stochastic with apparent loss of encoding ability. These results have in1pIications in the clinical application of cochlear implants operating at high stimulus rates.
  • Item
    Thumbnail Image
    Temporal and entrainment response properties of anteroventral cochlear neurons to intra cochlear electrical stimulation in the cat [Abstract]
    Buden, S. V. ; Brown, M. ; Paolini, A. G. ; Clark, Graeme M. ( 1996)
    Frequency coding within the central auditory system involves both spatial and temporal components. The temporal coding of sound is based on the phase or time locked neural response seen to low frequency acoustic stimuli. The ability of neurons to respond in a sustained time locked manner will determine the degree of encoded temporal frequency information.
  • Item
    Thumbnail Image
    The temporal and entrainment response properties of neurons to intracochlear electrical stimulation [Abstract]
    Brown, Mel ; Buden, S. V. ; Paolini, A. G. ; Clark, Graeme M. ( 1996)
    Understanding temporal coding in the central auditory pathway following electrical stimulation is important for further development of speech processing strategies and will also lead to a better understanding of temporal coding of acoustic stimuli. The temporal coding of sound frequency is based on the phase or time locked neural response seen to low frequency acoustic stimuli. The ability of neurons to respond in a time locked manner may determine the degree of encoded temporal frequency information. Single unit electrophysiological studies have shown that the degree of response synchrony to charge balanced biphasic electrical stimuli is far greater than that seen to acoustic stimuli.
  • Item
    Thumbnail Image
    Response properties of neurons in the anteroventral cochlear nucleus of the cat to complex temporal patterns of electrical stimulation [Abstract]
    Brown, Mel ; Paolini, A. G. ; Clark, Graeme M. ( 1995)
    Complex temporal patterns of electrical stimulation may provide a better simulation of the acoustic input. Currently little is known about the physiological or psychophysical responses to variations of the time intervals between pulses and their relative amplitudes. This knowledge could lead to a new generation of speech processing strategies. In this investigation we are examining physiological responses of neurons in the anteroventral cochlear nucleus to electrical stimulation using the Melbourne/Cochlear scala tympani banded electrode array.