Graeme Clark Collection

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    A preliminary report on a multiple-channel cochlear implant operation
    Tong, Y. C. ; Black, R. C. ; Clark, Graeme M. ; Forster, I. C. ; Millar, J. B. ; O'Loughlin, B. J. ; Patrick, J. F. (Cambridge University Press, 1979)
    Intra-cochlear single-channel electrical stimulation has recently been attempted by Michelson (1971) and by House and Urban (1973). Douek et at. (1977) have described experiments with a single-channel promontory electrode system. It is generally accepted that a single-channel system is useful in conveying crude auditory information such as the presence of sounds and some prosodic features of speech (Bilger et al., 1977; Douek et al., 1977). (From Introduction)
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    A cochlear implant round window electrode array
    Clark, Graeme M. ; Patrick, J. F. ; Bailey, Q. (Cambridge University Press, 1979)
    One important aspect of cochlear implantation is the placement of a multiple-electrode array close to residual auditory nerve fibres so that discrete groups of fibres can be stimulated electrically according to the place basis of frequency coding. Furthermore, in patients who are postlingually deaf these electrodes should lie in relation to the nerve fibres which are responsible for transmitting the frequencies which are important in speech comprehension, viz. 300-3,000 Hz. The method of electrode insertion should also ensure that there is no significant damage to auditory nerve fibres.
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    A multiple-electrode cochlear implant
    Clark, Graeme M. ; Tong, Y. C. ; Bailey, Q. R. ; Black, R. C. ; Martin, L. F. ; Millar, J. B. ; O'Loughlin B. J. ; Patrick, J. F. ; Pyman, B. C. ( 1978)
    Interest in artificially stimulating the auditory nerve electrically for sensori-neural deafness was first sparked off by Volta in the 18th century. Count Volta, who was the first to develop the electric battery, connected up a number of his batteries to two metal rods which he inserted into his ears. Having placed the rods in his ears he pressed the switch and received "une secousse dans la tete" and perceived a noise like "the boiling of thick soup".
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    Design criteria of a multiple-electrode cochlear implant hearing prosthesis
    Clark, Graeme M. ; Black, R. C. ; Forster, I. C. ; Patrick, J. F. ; Tong, Y. C. ( 1978)
    Abstract not available due to copyright.
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    Implant designs for future coding strategies
    Patrick, J. F. ; Evans, A. R. ( 1995)
    This paper briefly describes the history of speech processing developments leading to the presently available Speak processing strategy. The similarities and differences of the Speak and Continuous Interleaved Sampling (CIS) strategies are then discussed and some recent key experimental observations are examined as a guide to potential future coding strategies. Key issues for future coding strategies and implant designs are the number of electrodes and stimulation rates in use. Consideration of these issues has led to development of a prototype implant to be used for advanced speech-processing research.
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    Speech processing for cochlear implants
    Tong, Y. C. ; Millar, J. B. ; Blamey, P. J. ; Clark, Graeme M. ; Dowell, R. C. ; Patrick, J. F. ; Seligman, P. M. (JAI Press Ltd, 1992)
    The cochlear implant is a hearing prosthesis designed to replace the function of the ear. The operation of the prosthesis can be described as a sequence of four functions: the processing of the acoustic signal received by a microphone; the transfer of the processed signal through the skin; the creation of neural activity in the auditory nerve; and the integration of the experience of this neural activity into the perceptual and cognitive processing of the implantee.
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    Recent developments with the Nucleus 22-electrode cochlear implant: a new two formant speech coding strategy and its performance in background noise
    Franz, Burkhard K-H. G. ; Dowell, Richard C. ; Clark, Graeme M. ; Seligman, Peter M. ; Patrick, James F. ( 1987)
    A clinical evaluation of speech processing strategies for the Nucleus 22-electrode cochlear implant showed improvements in understanding speech using the new F0F1F2 speech coding strategy instead of the F0F2 strategy. Significant improvement in closed-set speech recognition in the presence of background noise was an additional advantage of the new speech processing strategy.
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    A multiple-electrode intracochlear implant for children
    Clark, Graeme M. ; Blamey, Peter J. ; Busby, Peter A. ; Dowell, Richard C. ; Franz, Burkhard K-H. ; Musgrave, Gaye Nicholls ; Nienhuys, Terry G. ; Pyman, Brian C. ; Roberts, Susan A. ; Tong, Yit C. ; Webb, Robert L. ; Kuzma, Januz A. ; Money, David K. ; Patrick, James F. ; Seligman, Peter M. ( 1987)
    A multiple-electrode intracochlear implant that provides 21 stimulus channels has been designed for use in young children. It is smaller than the adult version and has magnets to facilitate the attachment of the headset. It has been implanted in two children aged 5 and 10 years. The two children both lost hearing in their third year, when they were still learning language. Following implantation, it was possible to determine threshold and comfortable listening levels for each electrode pair. This was facilitated in the younger child by prior training in scaling visual and electrotactile stimuli. Both children are regular users of the implant, and a training and assessment program has been commenced.
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    The histopathological effects of chronic electrical stimulation of the cat cochlea
    Shepherd, R. K. ; Clark, Graeme M. ; Black, R. C. ; Patrick, J. F. (Cambridge University Press, 1983)
    The success of a cochlear implant depends on stimulating an adequate number of viable spiral ganglion cells. The effect of chronic electrical stimulation on ganglion cells is therefore an important consideration when assessing the effectiveness and safety of such a device. The histopathological assessment of chronic unstimulated intracochlear electrodes is now well documented (Simmons, 1967; Clark, 1973; Clark et al, 1975; Schindler and Merzenich, 1974; Schindler, 1976; Schindler et al, 1977; Sutton et al, 1980). These experimental studies have used a variety of electrode designs, materials and surgical techniques. However, all have shown that chronic implantation has little effect on the peripheral nerves and the spiral ganglion cells adjacent to an implant, provided the insertion procedure is free of trauma and infection.
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    Design and fabrication of the banded electrode array
    Clark, Graeme M. ; Shepherd, R. K. ; Patrick, James F. ; Black, R. C. ; Tong, Y. C. ( 1983)
    A multiple-channel electrode array must meet certain design requirements; these are listed in TABLE 1. First, there should be no trauma associated with the surgical insertion, and if there is a need to replace the array, this procedure should also be atraumatic. Second, it should be biologically inert. This means that it should be biocompatible with the tissues. When placed in the cochlea, the array should also not predispose the patient to local infection, and this is particularly important in children, in whom recurrent middle ear infections could spread to the inner ear. There should also be no risk of carcinogenicity with long-term implantation. Third, the electrode array should be designed so that the stimulus current can be localized to discrete groups of nerve fibers, and it should also be possible to stimulate as many groups as possible from the total remaining nerve population. Fourth, with long-term stimulation, there should be no significant corrosion of the electrodes used, and the electrical stimulation should not lead to damage of the tissues in the cochlea, especially the residual nerve fibers. Fifth, the electrode array should be mechanically robust and stable. It should not be prone to break as a result of repeated stress by the acceleration of the head during everyday movements. The array should also be capable of being fixed in place so that it will not shift its position. Sixth, it is desirable that the means of fabrication of the multiple-channel array should be simple and inexpensive. (From Introduction)