Graeme Clark Collection

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    Experimental study on extracochlear electric stimulation [Abstract]
    Ni, Daofeng ; Shepherd, Robert K. ; Clark, Graeme M. ( 1992)
    The efficiency and feasibility of chronic extracochlear implantation and electric stimulation were studied in two adult cats and four 2-month kittens. The first electrode was placed on the round window by fixing the leadwire on the bridge of aditus between the middle ear and bulla cavity; the second electrode was placed on the surface of the tympanic promontory; the third was inserted into the temporal muscle out of the bulla and the forth fixed in transverse sinus with dental cement. ABRs and EABRs were recorded pre-and postoperatively and during electric stimulation.
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    Cochlear implantation in young children: studies on head growth, leadwire design and electrode fixation in the monkey model [Abstract]
    Burton, Martin J. ; Xu, J. ; Shepherd, R. K. ; Xu, S-A. ; Seldon, H. L. ; Franz, B. K-H. G. ; Clark, Graeme M. ( 1992)
    For the safety of cochlear implantation in children under two, the implant assembly must not adversely effect the tissue of compromise head growth. Furthermore, growth changes and tissue responses should not impair functioning of the device. Dummy receiver-stimulators, interconnect plugs and leadwire-lengthening systems have been implanted for periods of 40 months in the young monkey to most effectively model the implantation of the young human child. The results show that implanting a receiver-stimulator package has no effect on skull growth or brain tissue under the package. The system for fixing the electrode at the fossa includes proved effective. There was marked osteoneogenesis in the mastoid cavity and this also resulted in fixation of the leadwire outside the cochlea. This study provides evidence for the safety of cochlear implantation in young children.
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    Cochlear implantation in young children: long-term effects of implantation on the skull and underlying central nervous system tissues in a primate model [Abstract]
    Burton, Martin J. ; Shepherd, R. K. ; Xu, S-A. ; Clark, Graeme M. ( 1992)
    Recent independent studies reporting results obtained by profoundly deaf children implanted with the Melbourne 22-channel cochlear implant have provided further impetus for assessing the feasibility of implanting children under two. Studies in appropriate animal models must first establish the safety of this procedure.
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    Cochlear implantation in young children: long-term effects of implantation on normal hair cells and spiral ganglion cells in the monkey model [Abstract]
    Burton, Martin J. ; Shepherd, R. K. ; Xu, S-A. ; Clark, Graeme M. ( 1992)
    Recent independent results obtained by profoundly deaf children implanted with the Melbourne 22-channel cochlear implant (1) have provided further impetus. for examining thefeasibility of implanting children under two and children with profound deafness. Safety st1,ldies, in appropriate animal models, must first establish the safety of this procedure.