Graeme Clark Collection

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    A speech processing strategy for multiple-electrode cochlear implant prostheses
    Tong, Y. C. ; Clark, Graeme M. (Monash University Press, 1983)
    Speech studies in a number of research centres have shown that useful speech information could be presented to deaf patients using single or multiple electrode cochlear implant prostheses (Parking & Anderson, 1983). In our laboratory, speech processing strategies were formulated on the basis of psychophysical results. This paper examines the psychophysical characteristics of the hearing sensations produced by electrical stimulation using scala tympani electrodes in postlingually deaf patients; a speech processing strategy is then discussed on the basis of these characteristics.
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    Physiological and histopathological effects of chronic intracochlear electrical stimulation
    Shepherd, R. K. ; Clark, Graeme M. ; Black, R. C. (Monash University Press, 1983)
    Direct and r.f. currents are known to result in destruction of neural tissue. However, it is now apparent that non-destructive electrical stimulation can be achieved by the use of biphasic pulsatile stimuli (Lilly, 1960; Mortimer et al., 1970; Hughes et al., 1980). Although maximum biologically safe stimulation regimes have yet to be clearly defined, the evidence of a number of investigators suggests that charge density per phase and charge injection per phase are important parameters when establishing biologically safe levels of electrical stimulation (Pudenz et al., 1975; Pudenz et al., 1977; Brown et al., 1977; Babb et al., 1977). Furthermore, considerable attention has been given to ensure that the stimulus is not producing adverse electrochemical reactions that could result in physical or toxic injury to the biological environment. Brummer et al. (1977) have defined the upper limit of electrochemically safe electrical stimulation for platinum electrodes as charge balanced biphasic pulses at a maximum charge density of 300 ?C/cm2 geom./phase.
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    Selection of speech processing for cochlear implant prostheses
    Millar, J. B. ; Tong, Y. C. ; Clark, Graeme M. (Monash University Press, 1983)
    In this paper we consider a framework against which to discuss strategies for the design of speech processors for cochlear implant prostheses. We hope to encourage discussion of the bases for such a framework even though it may seem a distant objective owing to the large gaps in our understanding of several component parts of cochlear implant systems. The existence of such a framework would provide a background against which to view the current diverse cochlear implant systems and to evaluate their performance.
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    The implanted round window membrane in the cat [Abstract]
    Franz, B. ; Clark, Graeme M. ; Ng, J. ; Bloom, D. (Monash University Press, 1983)
    In cochlear implants the round window is convenient for the electrode insertion into the scala tympani because the surgical approach is reasonably easy and the inserted electrode lies close to systematically organised nerve fibres in the spiral lamina. However, complications might occur when a poor seal, extensive tissue damage or surgical asepsis are present that lead to a reduction in the nerve fibre population which is needed for electrical stimulation. Published articles available do not describe the role of the window membrane in cochlear implants. Probably this can be referred to the finidng of abundant scar tissue in the window niche and around the electrode giving the impression of a safely implanted electrode. This study performed on seven cats over 5 months was concerned with morphological properties of the implanted window membrane at different stages after implantation. In addition, horseradishperoxydase was used as a tracersubstance to give data concerning the sealing properties of the implanted round window membrane.
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    Initial results for six patients with a multiple-channel cochlear prosthesis
    Dowell, R. C. ; Brown, A. M. ; Seligman, P. M. ; Clark, Graeme M. (Monash University Press, 1983)
    A total of eight patients have been assessed with the multi-channel cochlear prosthesis at the University of Melbourne. The first two patients were implanted with a prototype device in 1978 and 1979, and their results with various speech evaluation procedures have been reported and summarized in detail elsewhere (Clark & Tong, 1982). Briefly, these results indicated that some very significant benefit could be obtained for these patients when using the cochlear prosthesis with external speech processing, particularly when using the device in conjunction with lipreading. It was also shown that some significant understanding of speech was possible without lipreading (open-set) for both patients, although this was fairly limited.
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    The auditory brainstem response in hearing and deaf cats evoked by intracochlear electrical stimulation
    Black, R. C. ; Clark, Graeme M. ; O'Leary, S. J. ; Walters, C. (Monash University Press, 1983)
    This study was performed to investigate in detail the auditory brainstem response (ABR) for intracochlear electrical stimulation. Brainstem response audiometry is a simple, noninvasive procedure with the responses under many stimulus conditions being readily understood in terms of single auditory nerve discharge properties. The amplitude and latency behaviour of the Nl brainstem response correlates well with that recorded directly from the auditory nerve (Huang & Buchwald, 1978). In addition, the brainstem response can be divided into frequency-specific components corresponding to tonotopical locations in the cochlea, as exhibited in the method of derived responses (e.g. Parker &Thornton, 1978). It is therefore well suited to both physiological and clinical investigation of auditory function and therefore should be useful in evaluating auditory function under conditions of electrical stimulation of the cochlea.
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    Electrical stimulation of the human cochlea: psychophysical and speech studies
    Clark, Graeme M. (Plenum Publishing Corporation, 1981)
    This report describes psychophysical and speech studies conducted on two of our post-lingually deaf patients implanted with the nature of the hearing sensations produced by the individual electrodes, and to investigate the feasibility of the transmission of speech information to higher centres by means of cadences of stimulation using on electrode at a time. Two totally deaf patients (MC1 and MC2) participated in these studies.
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    Speech processing for electrical stimulation of the auditory nerve
    Miller, J. B. ; Tong, Y. C. ; Blamey, P. J. ; Clark, Graeme M. ; Dowell, R. C. ; Seligman, P. M. ( 1986)
    The development of cochlear prostheses which provide hearing .sensation to those previously totally deaf by means of electro-neural stimulation has brought new hope for normal communication to a portion of the deaf community that had previously been beyond help by conventional hearing aids. A cochlear prosthesis provide hearing sensation by exciting nerve fibres in the auditory nerve using small electrical current passed through one or more electrode placed in or around the cochlea. Once this artificial link in the auditory information pathway has been established there still remain considerable challenge in the selection of appropriate coding of information to be transmitted along it. In this paper we consider the design of signal processing necessary for an effective speech perception, prosthesis via the electrical stimulation of the auditory nerve.
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    A formant-estimating speech processor for cochlear implant patients
    Blamey, P. J. ; Dowell, R. C. ; Brown, A. M. ; Seligman, P. M. ; Clark, Graeme M. (Speech Science and Technology Conference, 1986)
    A simple formant-estimating speech processor has been developed to make use of the "hearing" produced by electrical stimulation of the auditory nerve with a multiple-channel cochlear implant. Thirteen implant patients were trained and evaluated with a processor that presented the second formant frequency, fundamental frequency, and amplitude envelope of the speech. Nine patients were trained and evaluated with a processor that presented the first formant frequency and amplitude as well. The second group performed significantly better in discrimination tasks and word and sentence recognition through hearing alone. The second group also showed a significantly greater improvement when hearing and lipreading was compared with lipreading alone in a speech tracking task.
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    A model of auditory-visual speech perception
    Blamey, P. J. ; Clark, Graeme M. (Speech Science and Technology Conference, 1986)
    A mathematical model relating the probabilities of correctly recognizing speech features, phonemes, and words was tested using data from the clinical trial of a multiple-channel cochlear implant. A monosyllabic word test was presented to the patients in the conditions hearing alone (H), lipreading alone (L), and hearing plus lipreading (HL). The model described the data quite well in each condition. The model was extended to predict the HL scores from the feature recognition probabilities in the H and L conditions. The model may be useful for the evaluation of automatic speech recognition devices as well as hearing impaired people.