Graeme Clark Collection

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    Results for children and adolescents using the multichannel cochlear prosthesis [Abstract]
    Dowell, Richard C. ; Clark, Graeme M. ; Dettman, Shani J. ; Dawson, Pamela W. ( 1992)
    The first adolescent to use the 22-electrode cochlear prosthesis was Implanted In Melbourne in 1985 and the first child (less than 10 years), the following year. Since then, over 100 children have received the cochlear prosthesis in Australia and over 1200 worldwide. Detailed assessment of 200 children in the U.S.A., Australia and Germany lead to the market approval of the prosthesis by the U.S. Food and Drug Administration in July 1990. The analysis of results for these children has proven to be difficult due to the use of different tests in different places, the lack of appropriate assessment tools for young children, the wide range of performance, and the problems of cooperation for young children. Despite these problems, some trends are beginning to emerge in the speech perception results for implanted children. Children with a greater amount of auditory experience before becoming profoundly deaf tend to perform better, as do children with more experience with the cochlear prosthesis. Those with a greater number of electrodes in use also perform better, a result supported by adult studies. Although older prelinguistically deafened children do not perform as well as postlinguistically deafened adults, there appears to be little difference between results for pre-and post-linguistically deafened young children. These trends In speech perception results will be discussed in more detail.
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    Cochlear implantation for children: an update [Abstract]
    Clark, Graeme M. ; Pyman, Brian C. ; Webb, R. L. ; Dowell, R. C. ; Staller, S. J. ; Beiter, A. L. ; Brimacombe, J. A. ( 1992)
    The performance of the Nucleus 22 channel cochlear implant has been assessed on 142 English speaking children who have worn their device for at least 12 months. The safety of the device has been evaluated on 309 children. A significant improvement for prosody was observed in 66%, for closed-set words in 63% and open-set words in 46%, using electrical stimulation alone. Performance over time increased, especially for open-set speech tests. Prelinguistically deaf children had similar scores to postlinguistically deaf children from prosody and closed-set word tests, but scores were not as good for open-set word tests. Lipreading enhancement was assessed using the CID sentence test, and the mean lipreading-alone score of 51% increased significantly to 71% when lipreading was combined with electrical stimulation. Speech intelligibility was determined with McGarr material and 63% were significantly more intelligible after 12 months' implant experience. There were 6-8% medical/surgical complications compared to 12% for a comparable group of adults. In 2.6% surgical intervention was required and this was primarily for infection or necrosis of the flap.
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    The development of the Melbourne/Cochlear multiple-channel cochlear implant for profoundly deaf children
    Clark, Graeme M. ; Busby, Peter A. ; Dowell, Richard C. ; Dawson, Pamella W. ; Pyman, Brian C. ; Webb, Robert L. ; Staller, Steven J. ; Beiter, Anne L. ; Brimacombe, Judith A. ( 1992)
    In 1978-79, a speech processing strategy which extracted the voicing (FO) and second formant (F2) frequencies and presented these as rate and place of stimulation respectively to residual auditory nerve fibres was developed for the University of Melbourne's prototype multiple-channel receiver-stimulator (Clark et aI1977, Clark et a11978, Tong et aI1980). This speech processing strategy was shown to provide post linguistically deaf adults with some open-set speech comprehension using electrical stimulation alone, and considerable help when used in combination with lipreading (Clark et al 1981).
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    Speech perception, production and language results in a group of children using the 22-electrode cochlear implant
    Blamey, P. J. ; Dawson, P. W. ; Dettman, S. J. ; Rowland, L. C. ; Brown, A. M. ; Busby, P. A. ; Dowell, R. C. ; Rickards, F. W. ; Clark, Graeme M. ( 1992)
    Five children out of a group of nine (aged 5.5 to 19.9 years) implanted with the 22-electrode cochlear implant (Cochlear Ply. Ltd.) have achieved substantial scores on open-set speech tests using hearing without lipreading. Phoneme scores for monosyllabic words ranged from 40% to 72%. Word scores in sentences ranged from 26% to 74%. Four of these five children were implanted during preadolescence. The fifth child, who had a progressive loss and was implanted during adolescence after a short period of very profound deafness, scored highest on all speech perception tests. The remaining four children who did not demonstrate open-set recognition were implanted during adolescence after a long duration of profound deafness. Post-operative performance on closed-set speech perception tests was better than pre-operative performance for all children. Improvements in speech and language assessments were also noted. These improvements tended to be greater for the younger children. The results are discussed with reference to variables which may contribute to successful implant use: such as age at onset, duration of profound hearing loss, age at implantation, aetiology, educational program, and the type of training provided.
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    Evaluation of expandable leadwires for paediatric cochlear implants
    Xu, Shi-Ang. ; Shepherd, Robert K. ; Clark, Graeme M. ; Tong, Yit C. ; Williams, John F. ( 1993)
    The development of cochlear implants for use in very young children (1-2 years old) will require techniques designed to accommodate temporal bone growth. Previous anatomic studies have shown that the leadwire of a cochlear implant must be capable of expanding up to 20 mm between the round window and the implanted receiver-stimulator in response to skull growth. In the present study morphologic and biomechanical evaluation of five expandable leadwire designs was conducted following their implantation in young cats. Two helical shaped leadwire designs frequently exhibited extensive fibrous tissue adhesions and broke during long-term implantation. In contrast, thin, flexible Silastic envelopes were effective in minimizing tissue adhesions. Residual V- and Z-shaped leadwires, placed in these envelopes, showed little evidence of fibrous tissue adhesions following implantation periods of up to 2 years. Moreover, these leadwires readily expanded both during the growth of the animal and when biomechanical expansion studies performed at the completion of the implant period. These expandable leadwire designs appear to be appropriate candidates for use in pediatric cochlear implants.
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    Paediatric cochlear implantation: radiologic observations of skull growth
    XU, JIN ; Shepherd, Robert K. ; Xu, Shi-Ang ; Seldon, H. Lee ; Clark, Graeme M. ( 1993)
    We investigated the effects of long-term implantation of auditory prostheses on skull growth in young animals. Four monkeys were implanted with dummy cochlear implants at 6 months of age. To simulate implantation in children, the bed for the receiver-stimulator or interconnecting plug was drilled across a calvarial suture down to the underlying dura. Plain skull oentgenograms were periodically taken to monitor head growth for up to 3 years after implantation. These longitudinal measurements revealed no significant asymmetric skull growth. Postmortem measurements using computed tomographic scans confirmed these results and showed no significant difference in the intracranial volumes between the implanted and control sides of each animal or between experimental and nonimplanted control monkeys. These results suggest that long-term cochlear implantation in very young children will not cause any significant deformity of the skull.
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    The postnatal growth of the temporal bone and its implications for cochlear implantation in children
    Dahm, Markus C. ; Shepherd, Robert K. ; Clark, Graeme M. ( 1993)
    The postnatal growth of the human temporal bone was examined by direct anatomical measurements on 60 cadaver specimens of all ages. The bones were dissected as one would perform cochlear implant surgery using a posterior tympanotomy approach. Nineteen anatomical /surgical landmarks with implications for cochlear implant surgery were identified on each bone and the distance between these points measured. The temporal hone was found to be a complex structure, phylogenetically, anatomically and functionally consisting of four different parts with independent postnatal development. The inner and middle cars were adult size at birth. The external auditory canal and most parts of the temporal hone were subject to significant lateral growth. The size of the pneumatised mastoid increased in all directions. In the facial recess, however, no postnatal growth was observed. Between birth and adulthood an average of 12 mm (SD 5 mm) of growth was seen directly between the sino-dural angle and the round window, the landmarks approximating the Implantation site for the receiver-stimulator and the electrode entry point into the inner car. However, if an electrode leadwire is fixed at a cortical fixation site such as the posterosuperior point of Macewen's triangle, the leadwire would be subject to approximately 20 mm of growth. These results indicate that a paediatric cochlear implant design incorporating an expandable leadwire to accommodate this growth should allow up to 25 mm of leadwire lengthening. The fossa incudis showed no growth relative to the round window and was found to be a convenient fixation site for the electrode array close to the cochlea. From an anatomical and surgical point of view, cochlear implantation in very young children is feasible, provided the electrode array is secured and the design accommodates for controlled leadwire lengthening.
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    The perception of vowels by hearing impaired children [Abstract]
    Busby, P. A. ; Tong, Y. C. ; Clark, Graeme M. ( 1982)
    This paper reports the results of a series of closed-set vowel identification experiments with four congenitally hearing impaired children (age 13 years) with moderate to profound bilateral sensorineural losses. Material was presented under three test conditions: hearing alone, through currently worn hearing aids; lipreading alone; and hearing plus lipreading. Analysis of the results using multidimensional scaling and hierarchical clustering revealed a strong relationship between the perceptual organisation of the responses and the physical attributes of the method of signal presentation. In the case of acoustic signals, the results indicated a perceptual organisation describable in terms of the duration of the vowel and the relative frequencies of the first and second formant. For visual signals, the perceptual organisation correlated with characteristics of lip-shaping during production. These results indicated that the subjects attempted to use similar perceptual cues as the normally hearing population. The relationship between the perceptual organisation of the acoustic stimuli and the aided audiogram is also discussed.
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    Expandable leadwires for a paediatric cochlear implant [Abstract]
    Xu, Shi-Ang. ; Shepherd, Robert K. ; Clark, Graeme M. ( 1993)
    Anatomic studies of skull growth have shown an increase (about 20 mm) in the distance between the round window and the asterion where the receiver-stimulator is usually located. In order to accommodate the skull growth of young patients, an expandable leadwire connecting the receiver-stimulator and the electrode array is necessary. Several expandable leadwires were evaluated in experimental animals, including helical leadwires protected by Silastic tubes and leadwires, with "V" or "W"-shaped levels in a single phase, and protected by thin Silastic or Teflon bags. The leadwires together with their controls were implanted on young animal's scapulae, temporal and parietal bones and in subcutaneous tissue. The in vivo expansion of the leadwire was monitored by periodic x-ray examination and the force to expand the leadwire was measured at the completion of implantation. The results showed that helical leadwires weresurrounded by fibrous tissue and a large force was required to expand them. The V or W-shaped leadwires were able to expand up to 20 mm in vivo and only a moderate force was required to expand them. For most of the cases, there was none or little fibrous tissue in Silastic or Teflon bags. The results indicated that for a paediatric cochlear implant, leadwires with V or W-shaped levels could, expand and biocompatible envelopes could effectively protect the leadwires from being bound by fibrous tissue.
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    Paediatric cochlear implant surgery [Abstract]
    Webb, R. L. ; Clark, Graeme M. ; Pyman, B. C. ( 1992)
    The operation in children is similar to that in adults, but special care needs to be taken with the skin flap, the anchoring of the electrode array and the sealing of .the cochleostomy. Research into the effects of head growth and otitis media in an implanted ear indicates that these should not be a problem. Surgical complications are also similar to those in adults, with the most common being related to the skin flap. The major complication rate at 4 % is slightly less than that in adults and most of these get effective implant function.