Graeme Clark Collection
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ItemCritical bands following the selective destruction of cochlear inner and outer hair cells( 1979)Critical bandwidths and absolute intensity thresholds were measured in cats before and after kanamycin treatment which induced selective inner and outer hair cell losses. Hair cell losses were measured from cochleograms constructed from surface preparations of the organ of Corti. Results suggested that, for the test frequencies and stimulus intensities employed, critical bandwidths were not affected for frequencies tonotopically located in cochlear regions where only outer hair cells were lost. Critical bands were widened or not measurable only when inner hair cell losses exceeding 40% were also associated with complete loss of outer hair cells. The experiment suggests that cochlear frequency selectivity can be mediated by inner hair cells alone.
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ItemPsychophysical studies with two binaural cochlear implant subjects( 1997)Abstract not available due to copyright.
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ItemEngineering(Singular Publishing, 1997)The last two decades have seen major advances in cochlear implants for profoundly deaf people. Implants are now used by severely to profoundly deaf adults and children in almost every phase of daily life. They have become an established treatment, and today's expectations for all aspects of the cochlear implant system are much greater than they were for the experimental devices of the early 1980s. Hardware designs have improved to meet clinical and research demands, technological developments have made the devices smaller and more reliable, and speech processing research has yielded a series of improvements in patient benefit.
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ItemThe Melbourne Cochlear Implant Clinic program(Singular Publishing, 1997)The Melbourne Cochlear Implant Clinic program involves a multidisciplinary clinical team, collaborating with those engaged in more fundamental research, and with the biomedical company Cochlear Limited. This chapter reflects the contributions of many professionals to managing children with cochlear implants.
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ItemChronic electrical stimulation of the auditory nerve at high rates: I. Effect on residual hearing [Abstract]( 1996)In addition to direct excitation of auditory nerve fibres, cochlear implant patients with small amounts of residual hearing may receive important additional auditory cues via electrophonic activation of hair cells 1. Before incorporating electrophonic hearing into speech processing strategies, the extent of hair cell survival following cochlear implantation must first be determined. We have recently demonstrated widespread survival of hair cells apical to electrode arrays implanted for periods of up to three years, the present report describes the effects of chronic electrical stimulation on hair cell survival.
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ItemChronic electrical stimulation of the auditory nerve at high rates: II. Cochlear pathophysiology [Abstract]( 1996)A major factor in the improved performance of cochlear implant patients has been the use of high stimulus rate speech processing strategies. While these strategies show clear clinical advantage, we know little of their long-term safety. Indeed, recent studies have indicated that high stimulus rates at intensities above clinical limits, can result in neural damage as a result of prolonged neuronal hyperactivity. The present study was designed to evaluate the effects of chronic electrical stimulation of the auditory nerve at high rates, using intensities within clinical limits.
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ItemSpatial representation of the cochlea within the inferior colliculus of neonatally deafened kittens following chronic electrical stimulation of the auditory nerve [Abstract]( 1995)The orderly tonotopic representation of the cochlea is accurately reproduced within the central auditory system of normal hearing animals. Any degradation of this representation as a result of a neonatal hearing loss or chronic electrical stimulation during development could have important implications for the use of multichannel cochlear implants in young children. In the present study we have used 2-deoxyglucose autoradiography (2-00) to examine the topographic representation of the cochlea within the inferior colliculus (IC) of neonatally deafened kittens following periods of chronic intracochlear electrical stimulation.
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ItemControl strategies for neurons modelled by self-exciting point processes [Abstract]( 1995)Abstract not available due to copyright.
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ItemMultichannel auditory brainstem implants: an Australian case study [Abstract]( 1996)The multichannel Auditory Brainstem Implant (ABI) is an implantable device designed to restore a level of auditory perception in patients with bilateral acoustic neuromas, where the removal of the tumours is expected to result in a total loss of hearing. As with the cochlear implant, the ABI utilises an externally worn speech processor and headset, together with a surgically-placed receiver-stimulator and electrode array. The electrode array, developed through the collaboration of the House Ear Institute in the United States and Cochlear Corporation, consists of eight electrodes on a carrier, which is placed on the surface of the brainstem in the area of the cochlear nucleus.
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ItemCurrent trends in speech perception performance in adult cochlear implant patients [Abstract]( 1996)In 1994, Cochlear Pty. Ltd. (Now Cochlear Limited) released a new speech processor, the Spectra 22, for use with the Nucleus 22-channel cochlear implant. The Spectra 22 speech processor incorporates a new speech processing strategy called SPEAK, which is based upon research conducted by the University of Melbourne. This paper reports post-operative scores on open-set word and sentence materials for adult patients in the Melbourne Cochlear Implant Clinic who have been started up with the Spectra 22 speech processor.