Graeme Clark Collection

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    The effects of electrode position and stimulus period on the hearing sensations in a multiple-channel cochlear implant patient [Abstract]
    Tong, Y. C. ; Blamey, P. J. ; Dowell, R. C. ; Clark, Graeme M. ( 1981)
    Abstract not available due to copyright.
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    Perceptual dissimilarity and discrimination studies using two-electrode stimulation with a multiple-channel cochlear implant patient [Abstract]
    Dowell, R. C. ; Tong, Y. C. ; Blamey, P. J. ; Clark, Graeme M. ( 1981)
    Abstract not available due to copyright.
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    Pitch and loudness studies on a multiple-channel cochlear implant patient [Abstract]
    Blamey, P. J. ; Tong, Y. C. ; Dowell, R. C. ; Clark, Graeme M. ( 1981)
    Abstract not available due to copyright.
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    Histopathology of the binaural cochlear implant subject [Abstract]
    Yukawa, K. ; O'Leary, S. J. ; Clark, Graeme M. ( 2001)
    Binaural hearing improves speech reception in noise, and is necessary for sound localisation. Normal hearing subjects use both interaural time, and intensity, differences to localise sound. This study investigates why sound localisation in bilateral cochlear implantees is insensitive to interaural time differences (Hoesel 1993). We looked for evidence of neural degeneration in the auditory brainstem involved in binaural sound localisation, since this may have degraded the neural circuitry required to accurately code interaural time delays. Method: The brainstem of a bilateral cochlear implantee was prepared for light microscopy by embedding it in paraffin, sectioning at 10 mm and staining sections with thionine or Luxol fast blue (LFB). The histological sections were digitised with NIH Image and 3-dimensional reconstructions made of the cochlear nucleus (CN) and superior olivary complex (SOC) with AnalysePC. Within the CN and the SOC, cell number and size were estimated by the physical dissector technique following thionine staining, and myelination of the nerve fibres was estimated using the optical density method following LFB staining. Results: A reduction in cell size (from thionine staining) and myelination (from LFB staining) was seen in both the CN and the SOC. Conclusions: These finding are consistent with neural degeneration within the auditory pathways. This may have lead to a degradation of the neural circuitry required to accurately detect interaural time delays.
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    Cochlear implants: climbing new mountains (The Graham Fraser memorial lecture)
    Clark, Graeme M. ( 2001)
    This 7th annual lecture was given as a special tribute to Graham Fraser (Figure 1). His enthusiasm, drive and constant search to find new ways to help deaf people, particularly with cochlear implants, has been most impressive. I remember with affection the visit Graham and his wife, Pat, made to Melbourne in 1992. There were lively discussions the past and future of cochlear implants. He would have had much to say about the new directors for the next decade. I hope to summarize some of those possibilities, and will refer in particular to research at our centres in Melbourne.
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    Short-term auditory memory in children using cochlear implants and its relevance to receptive language [Abstract]
    Dawson, Pam ; BUSBY, PETER ; MCKAY, COLETTE ; Clark, Graeme M. ( 2000)
    Current work indicates that many children using cochlear implants are able to hear fine differences between speech sounds but are not progressing as wel1 as expected in receptive language ability. There is anecdotal evidence from teachers that some children using cochlear implants have poor short-term auditory memory ability, which may be impeding their language development. Temporal ordering and short-term memory storage capacity involve higher order processing. Severe auditory deprivation prior to implantation may have caused auditory processing deficits at a cortical level. This study aims to assess short-term, sequential, auditory memory ability in children using cochlear implants and to determine the relationship between this ability and receptive language ability. Short-term auditory memory ability has not been previously investigated in profoundly deaf children using hearing aids and/or cochlear implants. Twenty-four children using the 22-electrode cochlear implant were tested on five short-term sequential memory tasks, three with auditory stimuli and two with visual stimuli. There were 8 children in each of the age groups; 5-6 years, 7-8 years, and 9-11 years. Twenty-four age-matched, normally hearing children served as a control group. Al1 children were also assessed on the receptive subtests of the CELF (Clinical Evaluation of Language Fundamentals) and on the nonverbal scale of the Kaufman Assessment Battery for Children (K-ABC) which measures nonverbal intelligence. This study assessed short-term auditory memory with tasks that required minimal language ability. Prior to the memory tasks, the child had to demonstrate accurate identification of the stimuli with a similar reaction time to the normally hearing controls. As expected there is a significant effect of age on memory performance for the 24 normally hearing children, with older children performing better than the younger children. The memory performance of the children using cochlear implants is therefore described in terms of its deviation from expected performance for a given chronological age. Preliminary results suggest that it is unlikely that auditory deprivation causes a memory deficit specific to the auditory modality. Performance on visual memory tasks is very similar to performance on analogous auditory memory tasks for a group of implant users. The performance of children using cochlear implants on a variety of memory tasks does not appear to be significantly different to that of normally hearing children who are of similar age and nonverbal intel1igence. In contrast their receptive language scores are substantially inferior.
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    The cochlear implant: a search for answers
    Clark, Graeme M. ( 2000)
    In 1967, when I commenced cochlear implant research, there was little that could be done to help profoundly deaf people. With normal hearing, sound vibrations are converted by hair cells in the inner ear into electrical signals. These produce temporal and spatial patterns of electrical responses in the auditory pathways. With a profound hearing loss the hair cells are absent, and amplifying sound with a hearing aid provides little help.
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    Cochlear implants in adults and children: comment
    Clark, Graeme M. ( 1997)
    This is a well-written review of the NIH Consensus report on cochlear implants for adults and children.
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    The Bionic ear towards 2000 and beyond: The William Carey Lecture 20th August 1998
    Clark, Graeme M. ( 1999)
    I consider it a great honour to have been invited to give the William Carey Lecture, especially when one considers how much Carey contributed to the welfare of people in India. He was an outstanding man with many gifts and wide-ranging interests and influence --in fields as diverse as botany, economics, medicine, print and communications technology, libraries, engineering, conservation, agriculture, social reform, astronomy and Indian religions. All his work was done in the name of God, and his Christian belief. My address is entitled The Bionic Ear: Towards 2000 and beyond. I want to emphasise from the start that research directions beyond the year 2000 are built upon the achievements of the past and the present. Furthermore, although we have made great progress with the Bionic Ear, we have some distance to go before we can give most people near normal hearing.
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    Speech perception in implanted children: influence of preoperative residual hearing on outcomes [Abstract]
    Cowan, R. S. C. ; Barker, E. J. ; Pegg, P. ; Dettman, S. ; Rennie, M. ; Galvin, K. ; Meskin, T. ; Rance, G. ; Cody, K. ; Sarant, J. ; Larratt, M. ; Latus, K. ; HOLLOW, RODNEY ; Rehn, C. ; Dowell, R. C. ; Pyman, B. ; Gibson, W. P. R. ; Clark, Graeme M. ( 1998)
    Since the first child was implanted with the Nucleus 22-channel prosthesis in Melbourne in 1985, several thousand children world-wide have now benefitted from this technology. More effective paediatric assessment and management procedures have now been developed, allowing cochlear implants to be offered to children under the age of 2 years. Improvements in speech processing strategy have also been implemented in the Nucleus implant system, resulting in increased mean speech perception benefits for implanted adults. Although a range of performance on formal measures of hearing, speech or language has been reported for children using implants, results from the first decade of implant experience consistently show that significant benefits are available to children receiving their implant at an early age. Reported speech perception results for implanted children show that a considerable proportion (60%) of paediatric patients in the Melbourne and Sydney clinics are able to understand some open-set speech using electrical stimulation alone. These results, and the upward trend of mean speech perception benefits shown for postlinguistically deafened adults have raised questions as to whether severely, or severely-to-profoundly deaf children currently using hearing aids would in fact benefit more from a cochlear implant. To investigate the potential influence of the degree of preoperative residual hearing on postoperative speech perception, results for all implanted children in the Melbourne and Sydney cochlear implant programs were analysed. Results showed that as a group, children with higher levels of preoperative residual hearing were consistently more likely to achieve open-set speech perception benefits. Potential factors in this finding could be higher levels of ganglion cell survival or greater patterning of the auditory pathways using conventional hearing aids prior to implantation. Conversely, children with the least preoperative residual hearing were less predictable, with some children achieving open-set perception, and others showing more limited closed-set benefits to perception. For these children, it is likely that preoperative residual hearing is of less significance than other factors in outcomes.