Graeme Clark Collection

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    Cochlear implants
    Clark, Graeme M. (Springer, 2003)
    Over the past two decades there has been remarkable progress in the clinical treatment of profound hearing loss for individuals unable to derive significant benefit from hearing aids. Now many individuals who were unable to communicate effectively prior to receiving a cochlear implant are able to do so, even over the telephone without any supplementary visual cues from lip reading. The earliest cochlear implant devices used only a single active channel for transmitting acoustic information to the auditory system and were not very effective in providing the sort of spectrotemporal information required for spoken communication. This situation began to change about 20 years ago upon introduction of implant devices with several active stimulation sites. The addition of these extra channels of information has revolutionized the treatment of the profoundly hearing impaired. Many individuals with such implants are capable of nearly normal spoken communication, whereas 20 years ago the prognosis for such persons would have been extremely bleak. (From Introduction)
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    Historia del implante cochlear nucleus
    Clark, Graeme M. (Masson, 2002)
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    Cochlear implants for adults and children
    Clark, Graeme M. (Martin Dunitz, 2002)
    Cochlear implants which use multiple-electrode speech-processing strategies are now established clinical entity for children and adults, as a result, preoperative selection and (re)habilitation are key issues. It is hard to realize that it was only in the 1960s and 1970s when many scientists and clinicians said that successful cochlear implants were not possible in the foreseeable future. The questions that had to be addressed by a multi disciplinary research effort are discussed, and the solutions achieved from the University of Melbourne's perspective are presented. However, the main aim of this chapter is to focus on preoperative selection, and (re)habilitation, including the results obtained. These issues are discussed primarily with reference to data from the University of Melbourne's Cochlear Implant Clinic at the Royal Victorian Eye and Ear Hospital. As this is a book on audiological medicine only, an overview of surgical principles is presented. The surgical management of the patient is, of course, very important, so for more details the reader is referred elsewhere. Cochlear implantation has also been the subject of quite intense ethical debate, particularly over its use for children. For this reason, a discussion of ethical issues is included. Finally, the chapter concludes with a vision of research in the next Millennium.
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    Contributing factors to improved speech perception in children using the nucleus 22-channel cochlear prosthesis
    Cowan, Robert S. C. ; Galvin, Karyn L. ; KLIEVE, SHARON ; Barker, Elizabeth J. ; Sarant, Julia Z. ; DETTMAN, SHANI ; Hollow, Rod ; RANCE, GARY ; Dowell, Richard C. ; PYMAN, BRIAN ; Clark, Graeme M. ( 1997)
    It has been established that use of multiple-channel intracochlear implants can significantly improve speech perception for postlinguistically deafened adults. In the development of the Nucleus 22-channel cochlear implant, there have been significant developments in speech processing strategies, providing additional benefits to speech perception for users. This has recently culminated in the release of the Speak speech processing strategy, developed from research at the University of Melbourne. The Speak strategy employs 20 programmable bandpass filters which are scanned at an adaptive rate, with the largest outputs of these filters presented to up to ten stimulation channels along the electrode array. Comparative studies of the Speak processing strategy (in the Nucleus Spectra-22 speech processor), with the previously-used Multipeak (Multipeak) speech processing strategy (in the Minisystem-22 speech processor), with profoundly deaf adult cochlear implant users have shown that the Speak processing strategy provides a significant benefit to adult users both in quiet situations and particularly in the presence of background noise. Since the first implantation of the Nucleus device in a profoundly hearing-impaired child in Melbourne in 1985, there has been a rapid growth in the number of children using this device. Studies of cochlear implant benefits for children using the Nucleus 22-channel cochlear implant have also shown that children can obtain significant benefits to speech perception, speech production and language, including open-set understanding of words and sentences using the cochlear implant alone. In evaluating contributing factors to speech perception benefits available for children, four specific factors are important to investigate: (1) earlier implantation -resulting from earlier detection of deafness; (2) improved hardware and surgical techniques -allowing implantation in infants; (3) improved speech processing, and (4) improved habilitation techniques. Results reported previously have been recorded primarily for children using the Multipeak strategy implemented in the MSP speech processor. While it is important to evaluate the factors which might contribute to improvements in speech perception benefits, an important question is the effect of improved speech processing strategy, since this will determine what is perceived through the device. Given that adult patients changing to the Spectra speech processor had also shown improved perception in noisy situations, and the fact that children are in general in noisy environments in the classroom setting for a large proportion of their day, it was of obvious interest to evaluate the potential for benefit in poor signal-to-noise ratios from use of the Speak processing strategy and from specific training in the ability to perceive in background noise. The study was aimed at evaluating whether children who were experienced in use of the Multipeak speech processing strategy would be able to changeover to the new Speak processing strategy, which provides a subjectively different output. Secondly, the study aimed to evaluate the benefits which might accrue to children from use of controlled habilitation in background noise.
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    Is age at cochlear implantation in children important? A 2-deoxyglucose study in cats.
    Seldon, H. Lee ; Kawano, Atsushi ; Clark, Graeme M. ( 1997)
    Should one implant prelinguistically deaf children at the earliest possible age or is it better to wait a couple of years? In normally hearing kittens functional auditory development is completed, up to the level of the inferior colliculus (IC), by 30 days after birth (DAB) [1]. However, in deaf kittens stimulation with a cochlear implant can alter the IC map even at ages up to 120 DAB [2]. In normally hearing children the auditory brainstem response approximates the adult form by the age of 2 years. Studies of deaf children with cochlear implants have indicated that implantation by the age of 5-6 yields a high success rate. We implanted neonatally deafened kittens at different ages, stimulated them for long periods, then looked at the spread of 2-deoxyglucose (2-DG) in the IC. If age is a factor in plasticity in deaf cats, then the distribution of 2-DG uptake should vary with age at implantation.
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    Engineering
    Patrick, James F. ; Seligman, Peter M. ; Clark, Graeme M. (Singular Publishing, 1997)
    The last two decades have seen major advances in cochlear implants for profoundly deaf people. Implants are now used by severely to profoundly deaf adults and children in almost every phase of daily life. They have become an established treatment, and today's expectations for all aspects of the cochlear implant system are much greater than they were for the experimental devices of the early 1980s. Hardware designs have improved to meet clinical and research demands, technological developments have made the devices smaller and more reliable, and speech processing research has yielded a series of improvements in patient benefit.
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    The Melbourne Cochlear Implant Clinic program
    Cowan, Robert S. C. ; Clark, Graeme M. (Singular Publishing, 1997)
    The Melbourne Cochlear Implant Clinic program involves a multidisciplinary clinical team, collaborating with those engaged in more fundamental research, and with the biomedical company Cochlear Limited. This chapter reflects the contributions of many professionals to managing children with cochlear implants.
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    Surgery
    Clark, Graeme M. ; Pyman, Brian C. ; Webb, Robert L. (Singular Publishing, 1997)
    Cochlear implant surgery should be undertaken only after the cochlear implant team has established that the child is not achieving useful communication with a hearing aid. This can be difficult because of poor language development in deaf children in this age group or because the child is at a preverbal stage and too young for the use of formal assessment tests. The child's unaided and aided thresholds, however, are important for assessment, as are his or her communication skills. These need to be evaluated by an experienced paediatric audiologist.
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    Preoperative medical evaluation
    Clark, Graeme M. ; Pyman, Brian C. (Singular Publishing, 1997)
    The aim of the medical assessment of infants and children is to determine the cause, severity and duration of any hearing loss as well as the presence of any medical conditions that may influence their management with a cochlear implant. There should also be an initial assessment of the child's communication skills and the parental expectations for his or her education.
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    Introduction
    Clark, Graeme M. ; Cowan, Robert S. C. ; Dowell, Richard C. (Singular Publishing, 1997)
    From the time single-channel cochlear implants were first implanted in children in the early 1980s in Los Angeles (Laxford et al 1987) closely followed in 1985 by the multiple-channel cochlear implant in Melbourne (Clark et al 1987a, 1987b) there has been a considerable expansion in the work to apply the multiple-channel cochlear implant to infants and young children.