Graeme Clark Collection
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ItemThe effects of electrode position and stimulus period on the hearing sensations in a multiple-channel cochlear implant patient [Abstract]( 1981)Abstract not available due to copyright.
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ItemPerceptual dissimilarity and discrimination studies using two-electrode stimulation with a multiple-channel cochlear implant patient [Abstract]( 1981)Abstract not available due to copyright.
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ItemPitch and loudness studies on a multiple-channel cochlear implant patient [Abstract]( 1981)Abstract not available due to copyright.
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ItemResults in children using the 22 electrode cochlear implant [Abstract]( 1989)Abstract not available due to copyright.
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ItemThe histopathology of the human temporal bone and auditory central nervous system following cochlear implantation in a patient: correlation with psychophysics and speech perception results( 1988)Cochlear implantation has become a recognised surgical procedure for the management of a profound-total hearing loss, especially in patients who have previously had hearing before going deaf (postlingual deafness). Nevertheless, it is important for progress in the field that patients who have had a cochlear implant, bequeath their temporal bones for research. This will then make it possible to further assess the safety of the procedure, and the factors that are important for its effectiveness. Biological safety has been assessed in a number of studies on animals, in particular, the biocompatibility of the materials used (1,2), the histopathological effects of long-term implantation on the cochlea (3, 4, 5, 6, 7, 8), and the effects of chronic electrical stimulation on the viability of spiral ganglion cells (9, 10, 11, 12). In studying the temporal bones of deceased cochlear implant patients it is possible to help establish that the animal experimental results are applicable to Man. Surgical trauma has been most frequently evaluated by inserting electrodes into cadaver temporal bones. It is important, however, to examine bones that have been previously implanted surgically to ensure that the cadaver findings are applicable to operations on patients. The effectiveness of cochlear implantation can be studied by correlating the histopathological findings, the dendrite and spiral ganglion cell densities, in particular, with the psychophysical and speech perception results. Other benefits also accrue, for example, establishing the accuracy of preoperative X-rays and electrical stimulation of the promontory in predicting cochlear pathology and spiral ganglion cell numbers. For the above reasons it has been especially interesting to examine both the temporal bones and central nervous system from one of our patients (patient 13) who participated in the initial clinical trial of the Cochlear Proprietary Limited (a member of the Nucleus group) multiple-electrode cochlear prosthesis, and who died due to a myocardial infarction following coronary bypass surgery.
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ItemThe University of Melbourne/Nucleus cochlear prosthesis( 1988)This is a review of research to develop the University of Melbourne/Nucleus cochlear prosthesis for patients with a profound-total hearing loss. A more complete review can be obtained in Clark et al. A prototype receiver-stimulator and multiple-electrode array developed at the University of Melbourne was first implanted in a postlingually deaf adult patient with a profound-total hearing loss on 1 August 1978. A speech processing strategy which could help this patient understand running speech, especially when combined with lipreading was developed in 1978 following initial psychophysical studies. A prototype wearable speech processor was fabricated in 1979, that could provide significant help for the first two patients in understanding running speech when used in combination with lipreading compared with lipreading alone, and it also enabled them to understand some running speech when using electrical stimulation alone. An implantable receiver-stimulator and wearable speech processor embodying the principles of the prototype devices were then produced for clinical trial by the Australian biomedical firm, Nucleus Ltd, and its subsidiaries, Cochlear Pty Ltd and Cochlear Corporation. This cochlear implant was initially clinically trialled on six patients at The Royal Victorian Eye & Ear Hospital in 1982, and shown to give similar results to those obtained with the prototype device. In view of these findings a clinical trial was carried out for a Premarket Approval Application to the US Food and Drug Administration (FDA), and extended to a number of centres in the US, Canada, and West Germany. This clinical trial confirmed that patients could understand running speech when electrical stimulation was combined with lipreading, and that some patients could also understand running speech when using electrical stimulation alone. Today, more than 600 patients world-wide are using cochlear implants developed from the research described in this paper.
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ItemSpeech perception with cochlear implants and tactile aids [Abstract]( 1988)Abstract not available due to copyright.
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ItemEducational assessment and management of children with multichannel cochlear implants( 1987)This paper describes the assessment and training program to evaluate speech, language, and communication skills of profoundly deaf children during and after training. Two sensory aids/prostheses are used: hearing aids and the Nucleus multichannel cochlear implant. Using a single-subject time-series experimental design, children's speech, language, and communication skills are assessed. For speech skills, assessment includes formal tests of articulation and intelligibility, syllable stress and process analyses, analyses of suprasegmental features, and voice quality. For general communication abilities, conversational skills with different speakers, story production skills, comprehension and expression of procedural information, discourse skills, and a measure of conversational interaction skills (pragmatics) are analyzed at regular intervals. Regular observations also sample the subjects' mode and frequency of interactions with individuals and groups in the school and home setting. Normative tests and formal analyses of language samples are also used to assess the overall language age of the child, vocabulary size, and kinds of expressive and receptive, syntactic, and semantic ability.
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ItemSpeech perception using a two-formant 22-electrode cochlear prosthesis in quiet and in noise( 1987)A new speech-processing strategy has been developed for the Cochlear Pty. Ltd. 22-electrode cochlear prosthesis which codes an estimate of the first formant frequency in addition to the amplitude. voice pitch and second formant frequencies. Two groups of cochlear implant patients were tested 3 months after implant surgery, one group (n= 13) having used the old (F0F2) processing strategy and the other (n=9) having used the new (F0FIF2) strategy. All patients underwent similar postoperative training programs. Results indicated significantly improved speech recognition for the F0FIF2 group particularly on open set tests with audition alone. Additional testing with a smaller group of patients was carried out with competing noise (speech babble). Results for a closed set spondee test showed that patient performance was significantly degraded at a signal-to-noise ratio of 10 dB when using the F0F2 strategy, but was not significantly affected with the F0FIF2 strategy.
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ItemEvaluation of a two-formant speech-processing strategy for a multichannel cochlear prosthesis( 1987)Initial results with the two-formant speech-processing strategy (F0FIF2) confirm the advantage of a multichannel cochlear prosthesis capable of stimulating at different sites within the cochlea. The successful presentation of two spectral components by varying the place of stimulation leads to the possibility of presenting further spectral information in this manner. Because virtually all multichannel implant patients demonstrate good "place" (electrode site) discrimination, these more refined coding strategies should lead to benefits for the majority of implantees. Already, with the F0FIF2 strategy, we have a system that appears to provide some effective auditory-alone communication ability for the average patient.