Graeme Clark Collection
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ItemInsertion study using new peri-modiolar electrode array designs [Abstract]( 1999)Intracochlear multi-channel cochlear implants have been shown to successfully provide auditory information for profoundly deaf patients by electrically stimulating discrete populations of auditory nerve fibers via a scala tympani (ST) electrode array. Histological and radiological examination of implanted human temporal bones showed that the current straight Nucleus® array is usually positioned against the outer wall of the ST. An electrode array close to the modiolus could be expected to reduce stimulation thresholds and result in a more localized neural excitation pattern.
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ItemBenefits of pre-curved electrode arrays for the Nucleus multichannel cochlear implant [Abstract]( 1998)The purpose of the study was to evaluate whether placement of an electrode closer to the modiolus would provide a more efficient interface with the auditory nerve. A pre-curved, banded 22-electrode array has been developed. Following comprehensive safety studies, the array was inserted in three adult patients. Detailed x-ray analyses have been conducted to specify the positions of the electrode bands. Psychophysical studies have been conducted, within each subject, using electrodes which lie at differing distances from the modiolus. These studies have shown that as the distance from the modiolus decreased, electrode threshold currents decreased and dynamic ranges increased. Thresholds were lower than in a comparison group of standard array users. Forward masking studies showed current spread to be more focused at the electrodes lying closer to the modiolus. Electrode discrimination was also better at electrodes closer to the modiolus. JND for loudness, expressed as a function of dynamic range also decreased in this condition. Thus, a preliminary profile of the parameters of interest, for an improved implant design, suggest that an array which lies closer to the modiolus can result in lower current requirements and a more localised pattern of neural excitation.
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ItemSpeech perception & indirect benefits for severely hearing impaired children using cochlear implants [Abstract]( 1998)The benefits to speech perception, speech production, communication, and quality of life were investigated for severely hearing impaired children using cochlear implants and hearing aids. For the youngest children, assessments of psychological status, and use of a battery of cognitive and language tests were important factors in determining performance benefits prior to the child developing speech. For older children, the effects of increased one-to-one oral habilitation, and systematic encouragement of parental involvement were also investigated. Results suggested that parental support for consistent device use was an important factor in producing outcomes. Children with residual hearing were more likely to achieve open-set perception. Each child was also assessed for changes in quality of life, through use of a standardized health utility instrument. Results from the group were collated, and teamed with a costing assessment for the procedure, which allowed a complete cost-utility analysis to be completed. Results suggested that indirect benefits, such as the effects on speech production, usual activities, lower concentration, and less distress were ranked as more important than changes to hearing in a number of the children. Costs per QALY were consistent with those reported in the literature, and suggested that the cochlear implant is highly cost-effective as a medical technology.
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ItemA new pre-curved electrode array benefits as measured by initial psychophysics [Abstract]( 1998)Theory suggests that an electrode which lies close to the modiolus should provide a more efficient interface with the auditory nerve, although it is important to ensure that stimulating fields are not so intense as to risk neural damage. A pre-curved, banded 22-electrode array has been developed which, following evaluation for ease of insertion and comprehensive safety studies, has been inserted in three patients. Detailed X-ray analyses, in which the positions of the electrode bands are specified, have been carried out. This has enabled comparative detailed, psychophysical studies to be carried out, within each subject, between electrodes which lie at differing distances from the modiolus. These studies have shown that, as the as electrode distance from the modiolus decreased, threshold currents decreased and dynamic ranges increased. Thresholds are lower than in a comparison group of subjects fitted with straight arrays which had been similarly position specified. Extensive forward masking studies have shown that current spread was more focused at the electrodes closer to the modiolus. Electrode discrimination studies were carried out and in the loudness jittered condition, which is more representative of the dynamic speech signal, discrimination was better at the electrodes closer to the modiolus. Just Noticeable Differences for loudness, expressed as a function of dynamic range, also decreased in this condition. Thus, a preliminary psychophysical profile of the parameters of interest, for an improved implant design, indicate that an array which lies closer to the modiolus can result in lower current requirements and a more localised pattern of neural excitation.
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ItemThe development of a precurved cochlear implant electrode array and its preliminary psychophysical evaluation [Abstract]( 1998)A precurved banded electrode array may provide a better interface with the auditory neural pathways for cochlear implants, and provide better speech perception. A prototype arrray has been further evaluated for ease of insertion, siting within the cochlea and induction of any cochlear trauma. The arrays were inserted into the human cochlear under simulated surgery. The bones were embedded in Araldite, X-rayed and sectioned. X-ray reconstruction analyses of the position of the implanted array showed its insertion to be favourable. Cochlear implants with precurved arrays have been implanted in three patients. Psychophysical evaluation and X-ray analyses have shown that as electrode distance from the modiolus decreased: threshold current decreased; dynamic range increased; current spread as measured by forward masking studies, was more focused; electrode discrimination with loudness jitter (being abetter representation of the dynamic speech signal) improved; JNDs for loudness, expressed as a function of dynamic range, decreased.
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ItemComparison and alternate designs for peri-modiolar electrode arrays: insertion trauma and position [Abstract]( 1997)While it has been shown that the straight but flexible banded electrode array can be safely inserted into the scala tympani of the human cochlea, histological studies have revealed that the array lies along the outer walll.2. Since a profound total hearing loss is generally associated with a moderate to complete degeneration of the spiral ganglion peripheral process, these electrodes lie some distance from their target neural population -the spiral ganglion soma -located within Rosenthal's canal.
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ItemImplantation of the new nucleus C1-3 receiver stimulator and electrode array [Abstract]( 1997)There is an important need to fix the cochlear implant electrode array at a site close to the cochlea, so that the electrode will not slide out, or be subject to differential movement with growth changes. Fixation sites have been in the region of the posterior root of the zygoma and the floor of the antrum. Fixation has been by Dacron mesh ties platinum wire ties, or clips inserted with-special instruments. Biological cements have previously been tried but found to be toxic. The most ideal site is in the region of the cochleostomy.
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ItemAetiology of hearing loss in children presenting for cochlear implantation and outcomes [Abstract]( 1997)The aetiology of hearing loss has a significant bearing on the likely outcome of cochlear implantation and therefore is an important consideration in patient selection and workup. Disease processes which result in sensorineural hearing loss may be associated with other structural or functional neurological disorders, in addition to 'damage to the cochlea and auditory pathways.
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ItemSpeech perception results for children changing from multipeak to SPEAK speech processing strategy [Abstract]( 1996)In mid-1994, a new speech processing strategy termed SPEAK was introduced for the Nucleus Spectra-22 cochlear prostheses. To compare benefits in implanted children changing to the SPEAK strategy, speech perception in a group of twelve children from Melbourne and Sydney was evaluated. The children were assessed in quiet and in background noise.
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ItemFactors affecting speech perception in children cochlear 22-channel cochlear prosthesis [Abstract]( 1996)Since the implantation of the first children with the Nucleus 22-channel cochlear prosthesis in Melbourne in 1985, there have been rapid expansion world-wide in the number of children using this implant system. Longer-term experience with implanted children has led to improvements in paediatric assessment and management. Speech processing strategies have also been improved, resulting in a series of increases in speech perception benefits.