Graeme Clark Collection

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    The use of click-ABR and steady state evoked potentials for hearing assessment in young cochlear implant candidates [Abstract]
    Rance, G. ; Dowell, Richard, C. ; Richards, F. W. ; Clark, Graeme M. ( 1997)
    The accurate assessment of hearing thresholds in prospective cochlear implant candidates is essential. As the minimum age of implantation has reduced, audiologists have been faced with the complicated task of obtaining precise audiometric information in children whose immaturity may severely restrict the assessment process. Clearly for these young candidates, there is a place for a reliable, objective measure of residual hearing in the pre-operative test battery. This paper examines the degree of accuracy with which the click-ABR and the steady-state evoked potential (SSEP) techniques can provide estimates of hearing level in subjects with several profound hearing loss.
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    Speech perception benefits for children using the 22-channel Melbourne/cochlear hearing prosthesis [Abstract]
    Sarant, J.Z. ; Hollow, P.W. ; Clark, Graeme M. ; Dowell, Richard C. ; Cowan, Robert S.C. ; Pyman, B. C. ; Dettman, S. J. ; RANCE, GARY ; Barker, Elizabeth J. ( 1993)
    In 1985; the first child was implanted with the Cochlear 22-channel cochlear prosthesis at the University of Melbourne Royal Victorian Eye & Ear Hospital Cochlear Implant Clinic. There are now 42 children who have received the device in Melbourne. Analysis of patient details for these children show a very heterogeneous group, with a wide range in age, hearing thresholds, duration of deafness and aetiology. The major aetiologies found were either a congenital profound deafness.; or a hearing loss due to meningitis. In all but 3 cases, the children are using 15 or more electrodes in the array. Speech perception benefits have been analyzed according to a six-level hierarchical classification scheme. All of-the children achieved a minimum benefit of discrimination of suprasegmental information (Category 2), and 59% of the children achieved open-set understanding of unfamiliar speech material without the aid of lip-reading (Categories 5 & 6). Detailed analysis suggests that the majority of children achieving open-set speech perception benefits had more than one year of experience with their implant. and less than seven years of profound deafness prior to implantation.
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    Factors associated with open-set speech perception in children using the Cochlear multiple-channel prosthesis [Abstract]
    Yaremko, R. ; Rance, G. ; Sarant, Julia Z. ; Dawson, Pam W. ; Gibson, William P.R. ; Clark, Graeme M. ; Dowell, Richard C. ; Cowan, Robert S.C. ; Brown, Catherine D. ; Dettman, Shani J. ; Barker, Jane ; Barker, Elizabeth J. ( 1993)
    Since 1985, nearly 100 children have received the 22-channel cochlear prosthesis from the Melbourne and Sydney cochlear implant clinics. These two clinics account for the bulk of casesin Australia, and have similar management philosophies and selection criteria. The patient population represents a variety of etiologies, and ranges in age from 2 - 18 years of age. Bothcongenital and postlinguistic hearing losses are included. In order to assess benefit to speech perception in such a diverse group, the children's results have been tabulated according to a six level hierarchical scale of speech perception achievement. The scale ranges from category I,detection of sound only, to category 6, which includes significant perception scores for open-setwords and sentences. Analysis of the results shows that the majority of the children are achieving open-set speech perception benefits, and that results continue to improve with additional experience with their devices. There are a number of contributing factors to these open-set speech� perception results which have impact both on selection issues and on habilitation with different age ranges �of patients.
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    Multichannel cochlear implants in children: an overview of experimental and clinical results at the University of Melbourne [Opening Lecture]
    Shepherd, R. K. ; Dowell, R. C. ; Xu, S-A. ; McDermott, H. J. ; McKay, C. M. ; Clark, Graeme M. ( 1992)
    During the last decade there has been great progress in the clinical management of profound, postlinguistically deafened adults through the use of multichannel cochlear implants. The device developed by The University of Melbourne in association with Cochlear Pty Ltd, electrically stimulates selective regions of the auditory nerve using an array of 22 platinum (Pt) electrodes located in the scala tympani. Its development followed basic experimental studies and the development and evaluation of a prototype device in the 1970's. Following safety studies and a successful clinical trial, the Melbourne/Cochlear multichannel implant was approved for use in adults by the United States Food and Drug Administration (FDA) in 1985. More than 3000 patients throughout the world have since been implanted with this device, many being able to understand a significant amount of unfamiliar, connected speech without lipreading Following miniaturization of the implant, it became suitable for use with children. In 1990, after additional biological safety and clinical investigations, the FDA approved the use of the Melbourne/Cochlear multichannel implant for profoundly deaf children above the age of two years. And in 1991, the device received the medical device implantation approval certificate from the Japanese Government. The present paper presents an overview of our recent biological safety studies and clinical experience in children, and discusses the likely future development of these devices.
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    Cochlear implantation in young children: long-term effects of implantation on normal hair cells and spiral ganglion cells in the monkey model [Abstract]
    Burton, Martin J. ; Shepherd, R. K. ; Xu, S-A. ; Clark, Graeme M. ( 1992)
    Recent independent results obtained by profoundly deaf children implanted with the Melbourne 22-channel cochlear implant (1) have provided further impetus. for examining thefeasibility of implanting children under two and children with profound deafness. Safety st1,ldies, in appropriate animal models, must first establish the safety of this procedure.