Graeme Clark Collection

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Type: Conference Paper × Subject: cochlear implants × Subject: auditory nerve × Start date: 1980 × End date: 1989 ×

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    Electrical stimulation of the auditory nerve: stimulus induced reductions in neural excitability [Abstract]
    Shepherd, R. K. ; Clark, Graeme M. ( 1987)
    Electrical stimulation of the auditory nerve elicits highly synchronised neural activity (Javel et al., in press). As the stimulus current is increased the neural response becomes highly deterministic with every current pulse eliciting a spike even at stimulus rates of 600-800 pulses per second (pps). Our previous acute experimental studies have shown that high stimulus rates (> 200 pps) and high stimulus currents (> 1.0 mA) can result in temporary and sometimes permanent reductions in the excitability of the auditory nerve (Shepherd and Clark, 1986). The present study was designed to examine the mechanisms underlying these stimulus induced reductions in excitability. These results will have implications for the maximum safe and effective stimulus rates that can be employed in cochlear implants.