Graeme Clark Collection

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    "Cochlear View" and its application in cochlear implant patients [Abstract]
    Xu, J. ; Xu, S. A. ; Clark, Graeme M. ; Marsh, M. A. ( 1994)
    Recent advances in multichannel intracochlear implantation have generated interests in correlating individual stimulating electrodes to pitch perception. An appropriate radiographic technique is required to precisely document the location of the implanted intracochlear electrode array. Anatomical studies, including the measurements of the temporal bone using high-resolution CT films and 3D reconstruction from the petrous bone sections, were conducted to define the spatial position of cochlea in the skull. Thus, a "Cochlear View" was designed and introduced for postoperative radiological evaluation of multichannel intracochlear implantation. In this paper, a detailed radiographic method and radiological interpretation of the "Cochlear View" are described. A plain radiograph of the "Cochlear View" was taken of 120 patients who had received the Nucleus multichannel implant. Studies have shown that a plain radiograph of the "Cochlear View" provides sufficient information to correctly evaluate the results of implantation, including the insertion depth and position of individual electrodes. It plays an important role in guiding the management of frequency mapping and acts as a useful reference for further research purposes.
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    Paediatric cochlear implantation: radiological and histopathological studies of skull growth in the monkey
    Shepherd, R. K. ; XU, JIN ; Burton, Martin J. ; Xu, Shi-Ang ; Seldon, H. Lee ; Franz, Burkhard K-H. G. ; Clark, Graeme, M. ( 1993)
    The human skull undergoes significant growth within the first two years of life (Dahm et aI, 1992). Therefore, before children under two can be considered candidates for cochlear implantation, the effects of the surgical procedure on subsequent skull growth must be well understood. To evaluate the effects of implantation on skull growth four macaque monkeys were implanted with dummy cochlear implants at six months of age. To model the procedure in the very young child, the bed for the receiver-stimulator was drilled across a calvarial suture down to the underlying dura and an electrode array inserted into the scala tympani via a mastoidectomy and posterior,tympanotomy. Plain skull radiographs were perioqical1y taken to monitor skull growth for periods of up to three years following implantation. Their longitudinal measurements revealed no evidence of asymmetrical skull growth when compared with unimplanted control animals. Computer tomographic scans taken at post-mortem confirmed these findings. Finally, subsequent histopathological evaluation of the receiver-stimulator package bed indicated that it becomes obliterated by hard tissue, resulting in a localized flattening of the vault under the receiver-stimulator. However, this tissue exhibited histological evidence of sutures, indicating that the surgical procedure should not lead to premature sutural closure. In conclusion, the present experimental results suggest that long-term cochlear implantation in very young children will not lead to any significant skull deformity.
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    Investigation of curved intracochlear electrode arrays [Abstract]
    Xu, Shi-Ang ; Xu, J. ; Seldon, H Lee. ; Shepherd, R. K. ; Clark, G. M. ( 1992)
    It has been demonstrated that the Melbourne/Cochlear multi-channel cochlear implant is safe and effective for use in profoundly-totally deaf patients. Recent studies have highlighted the importance of deaf insertion and placing the electrodes closer to the spiral ganglion neurons. In order to improve the electrode insertion depth and proximity to the modiolus, we have investigated curved electrode arrays. Prototypes of such arrays and their accessory inserter have been made. Trial insertions were performed on skeletonized cochleae of human temporal bones. The preliminary results showed that, when compared with conventional straight electrode arrays, the curved arrays could be inserted deeper and located closer to the modiolus. These findings indicate that the curved --.~ electrodes currently under investigation should result in a reduction in stimulus threshold and improve pitch perception and may also result in the use of more channels of stimulation.