Graeme Clark Collection
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ItemA speech processing strategy for multiple-electrode cochlear implant prostheses(Monash University Press, 1983)Speech studies in a number of research centres have shown that useful speech information could be presented to deaf patients using single or multiple electrode cochlear implant prostheses (Parking & Anderson, 1983). In our laboratory, speech processing strategies were formulated on the basis of psychophysical results. This paper examines the psychophysical characteristics of the hearing sensations produced by electrical stimulation using scala tympani electrodes in postlingually deaf patients; a speech processing strategy is then discussed on the basis of these characteristics.
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ItemSelection of speech processing for cochlear implant prostheses(Monash University Press, 1983)In this paper we consider a framework against which to discuss strategies for the design of speech processors for cochlear implant prostheses. We hope to encourage discussion of the bases for such a framework even though it may seem a distant objective owing to the large gaps in our understanding of several component parts of cochlear implant systems. The existence of such a framework would provide a background against which to view the current diverse cochlear implant systems and to evaluate their performance.
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ItemThe implanted round window membrane in the cat [Abstract](Monash University Press, 1983)In cochlear implants the round window is convenient for the electrode insertion into the scala tympani because the surgical approach is reasonably easy and the inserted electrode lies close to systematically organised nerve fibres in the spiral lamina. However, complications might occur when a poor seal, extensive tissue damage or surgical asepsis are present that lead to a reduction in the nerve fibre population which is needed for electrical stimulation. Published articles available do not describe the role of the window membrane in cochlear implants. Probably this can be referred to the finidng of abundant scar tissue in the window niche and around the electrode giving the impression of a safely implanted electrode. This study performed on seven cats over 5 months was concerned with morphological properties of the implanted window membrane at different stages after implantation. In addition, horseradishperoxydase was used as a tracersubstance to give data concerning the sealing properties of the implanted round window membrane.
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ItemInitial results for six patients with a multiple-channel cochlear prosthesis(Monash University Press, 1983)A total of eight patients have been assessed with the multi-channel cochlear prosthesis at the University of Melbourne. The first two patients were implanted with a prototype device in 1978 and 1979, and their results with various speech evaluation procedures have been reported and summarized in detail elsewhere (Clark & Tong, 1982). Briefly, these results indicated that some very significant benefit could be obtained for these patients when using the cochlear prosthesis with external speech processing, particularly when using the device in conjunction with lipreading. It was also shown that some significant understanding of speech was possible without lipreading (open-set) for both patients, although this was fairly limited.
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ItemThe auditory brainstem response in hearing and deaf cats evoked by intracochlear electrical stimulation(Monash University Press, 1983)This study was performed to investigate in detail the auditory brainstem response (ABR) for intracochlear electrical stimulation. Brainstem response audiometry is a simple, noninvasive procedure with the responses under many stimulus conditions being readily understood in terms of single auditory nerve discharge properties. The amplitude and latency behaviour of the Nl brainstem response correlates well with that recorded directly from the auditory nerve (Huang & Buchwald, 1978). In addition, the brainstem response can be divided into frequency-specific components corresponding to tonotopical locations in the cochlea, as exhibited in the method of derived responses (e.g. Parker &Thornton, 1978). It is therefore well suited to both physiological and clinical investigation of auditory function and therefore should be useful in evaluating auditory function under conditions of electrical stimulation of the cochlea.
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ItemElectrical stimulation of the human cochlea: psychophysical and speech studies(Plenum Publishing Corporation, 1981)This report describes psychophysical and speech studies conducted on two of our post-lingually deaf patients implanted with the nature of the hearing sensations produced by the individual electrodes, and to investigate the feasibility of the transmission of speech information to higher centres by means of cadences of stimulation using on electrode at a time. Two totally deaf patients (MC1 and MC2) participated in these studies.
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ItemIntracochlear damage following insertion of the Nucleus 22 standard electrode array: a post mortem study of 14 implant patients( 2000)The insertion of an intracochlear electrode array may cause trauma to cochlear structures which can result in degeneration of neural elements, jeopardizing the potential benefits of electrical stimulation. Safety studies for the assessment of trauma associated with the Nucleus 22 standard electrode array involved animal experiments as well as insertion studies in post mortem temporal bones. However, there are only few histological studies of temporal bones from deceased cochlear implant patients. A review of our temporal bone collection of implantees originating from a variety of centres has been conducted to evaluate the effects of electrode insertion trauma associated with the Nucleus 22 standard array.
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ItemThe histological and physiological effects of the auditory brainstem prosthesis of the auditory pathway(Monduzzi Editore, 1997)To rehabilitate profoundly deaf patients who cannot benefit from the cochlear implant due to bilateral interruption of the auditory nerve, particularly from neurofibromatosis II, the histological and physiological effects of an auditory brainstem prosthesis on the cochlear nuclei of guinea pigs were examined in order to establish the safety and the efficacy of this prosthesis.
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ItemSpeech cues for cochlear implantees: spectral discrimination(Monduzzi Editore, 1997)The relationship between the ability of cochlear implantees to perceive speech and their ability to discriminate between stimulation on adjacent electrodes was investigated. Speech perception ability was assessed with monosyllabic words in 8 users Nucleus cochlear prosthesis. The ability of these subjects to discriminate between stimulation on adjacent electrodes, in of random loudness differences between electrodes was determined. Results were averaged in the apical, mid and basal regions of the cochlea. Regression analysis showed that speech perception ability and electrode discrimination ability were correlated in the apical to mid region of the cochlea. but the two factors were not correlated in the basal region. Therefore, these results suggest that implantees require the ability to discriminate between stimulation on adjacent electrodes in the apical to mid region of the cochlea in order to achieve high speech perception scores.
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ItemSpeech perception of hearing aid users versus cochlear implantees(Monduzzi Editore, 1997)Recent improvements in speech recognition abilities for profoundly deaf cochlear implantees suggests that some adults with a severe hearing impairment might benefit from a cochlear implant. Unfortunately, no studies have directly compared the speech perception abilities of the severely hearing impaired with those of cochlear implant users. An investigation of the speech perception performance of people with a severe hearing loss, who use hearing aids, was conducted in the Department of Otolaryngology at The University of Melbourne. Each participant (n=35) took part in a series of speech perception tests which included 11 vowel recognition tests, CNC words, CUNY sentences, and the Connected Speech Test. The results from these severely hearing impaired persons were compared to results from cochlear implant users. The group of severely hearing impaired adults performed better on tests of vowel and word perception but poorer on tests of open set sentence perception in comparison to a group of cochlear implant users.