Graeme Clark Collection

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    Chronic middle ear disease and cochlear implantation
    Donnelly, M. J. ; Pyman, B. C. ; Clark, Graeme M. ( 1995)
    Profound or total hearing loss can occur in the setting of chronic suppurative otitis media (CSOM), either coincidentally or secondary to the disease process. Obviously, inserting a foreign body through a potentially infected field into a space that communicates intracranially presents a challenging management problem. This paper presents the experience from the Melbourne Cochlear Implant Clinic (CIC) in implanting patients with bilateral CSOM. This is certainly not a common problem, as there have been only 3 cases from 121 implanted adults. However, we feel that it is an important issue with potentially devastating consequences. In addition, there are many countries in which bilateral CSOM is a more common problem and cause of profound or total hearing loss.
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    Initial investigation of the efficacy and biosafety of sodium hyaluronate (healon) as an aid to electrode array insertion
    Donnelly, M. J. ; Cohen, L. T. ; Clark, Graeme M. ( 1995)
    Stimulation of residual neural elements by electrodes inserted into the cochlea to produce the perception of speech and environmental sounds in profoundly deaf people is a fundamental aim of cochlear implantation. The multiple-channel cochlear implant utilizes the tonotopic arrangement of the organ of Corti to also achieve place pitch perception by stimulating different electrode bands. It may be possible to improve the range of pitches perceived by present cochlear implant patients by inserting the electrode array more deeply. To help achieve this, investigators have used sodium hyaluronate as a lubricant for electrode insertions. 1 It was felt deeper insertions were produced with sodium hyaluronate. Before introducing this substance as part of the surgical protocol for the Melbourne Cochlear Implant Clinic, it was decided to investigate its efficacy in aiding deeper insertions of the electrode. In addition, it was also necessary to determine if sodium hyaluronate, in conjunction with cochlear implantation, had adverse effects on the inner ear. This study was undertaken to address these issues.
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    Electrical stimulation of residual hearing in the implanted cochlea
    Clark, Graeme M. ; McAnally, K. I. ; Black, R. C. ; Shepherd, R. K. ( 1995)
    The average profoundly deaf person using a cochlear implant can now understand more speech than some severely to profoundly deaf people who use a hearing aid. For this reason there will be an increasing need to consider implanting people with residual hearing. In many of these people there could be significant hearing in the operated ear, as a majority of severely to profoundly deaf people are likely to have a symmetrical hearing loss. When three frequency average hearing thresholds were measured on 219 pensioners from the Australian National Acoustic Laboratories (H. Dillon, unpublished findings), 64% had less than a 10-dB difference between thresholds in each ear.
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    Cochlear implantation: osteoneogenesis, electrode-tissue impedance, and residual hearing
    Clark, Graeme M. ; Shute, S. A. ; Shepherd, R. K. ; Carter, T. D. ( 1995)
    This study was undertaken to find out how new bone is produced in the implanted cochlea, and the effects of fibrous tissue and new bone growth on electrode-tissue impedance. This knowledge is essential, as bone and fibrous tissue in the cochlea could account for variations in patients' speech perception performance. The study was also carried out to examine the effects of implantation on residual hearing. This information is also important, as cochlear implant speech perception results in profoundly deaf people are now better on average than severely or profoundly deaf people obtain with a hearing aid. Consequently, more people will need to be considered for cochlear implantation in ears with some residual hearing. In this case we need to know to what extent residual hearing is affected by implantation. (From Introduction)
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    Preliminary results for the Cochlear Corporation multielectrode intracochlear implant in six prelingually deaf patients
    Clark, Graeme M. ; Busby, Peter A. ; Roberts, Susan A. ; Dowell, Richard C. ; Blamey, Peter J. ; Mecklenburg, Dianne J. ; Webb, Robert L. ; Pyman, Brian C. ; Franz, Burkhard K. ( 1987)
    The preliminary results from this study indicate that some prelingually deaf patients may get worthwhile help from a multiple-electrode cochlear implant that uses a formant-based speech processing strategy. It is encouraging that these improvements can occur in young adults and teenagers. The results for two children are also encouraging. A 10-year-old child obtained significant improvement on some speech perception tests. It was easy to set thresholds and comfortable listening levels on a 5-year-old child, and he is now a regular user of the device. There are, however, considerable variations in performance among the prelingual patients, which may be related to the following factors: whether they have had some hearing after birth, the method of education used, the motivation of the patient, and age at implantation.
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    The histopathology of the human temporal bone following cochlear implantation in a patient: a summary
    Clark, Graeme M. ; Shepherd, R. K. ; Webb, R. L. ; Franz, B. K-H. ( 1987)
    The macroscopic and microscopic evaluation of the implanted and unimplanted temporal bones in a patient who had a cochlear prosthesis for 27 months prior to his death from cardiac disease has shown that the device is biocompatible, and does not lead to any significant adverse effects. The cause of deafness was meningitis.