Engineering and Information Technology Collected Works - Research Publications

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    Modelling and simulating retail management practices: a first approach
    Siebers, PO ; Aickelin, U ; Celia, H ; Clegg, CW (Inderscience Publishers, 2009)
    Context: The vaccine distribution for the coronavirus disease of 2019 (COVID-19) is a multicriteria decision-making (MCDM) problem based on three issues, namely, identification of different distribution criteria, importance criteria and data variation. Thus, the Pythagorean fuzzy decision by opinion score method (PFDOSM) for prioritising vaccine recipients is the correct approach because it utilises the most powerful MCDM ranking method. However, PFDOSM weighs the criteria values of each alternative implicitly, which is limited to explicitly weighting each criterion. In view of solving this theoretical issue, the fuzzy-weighted zeroinconsistency (FWZIC) can be used as a powerful weighting MCDM method to provide explicit weights for a criteria set with zero inconstancy. However, FWZIC is based on the triangular fuzzy number that is limited in solving the vagueness related to the aforementioned theoretical issues. Objectives: This research presents a novel homogeneous Pythagorean fuzzy framework for distributing the COVID-19 vaccine dose by integrating a new formulation of the Pythagorean fuzzy-weighted zero-inconsistency (PFWZIC) and PFDOSM methods. Methods: The methodology is divided into two phases. Firstly, an augmented dataset was generated that included 300 recipients based on five COVID-19 vaccine distribution criteria (i.e., vaccine recipient memberships, chronic disease conditions, age, geographic location severity and disabilities). Then, a decision matrix was constructed on the basis of an intersection of the ‘recipients list’ and ‘COVID-19 distribution criteria’. Then, the MCDM methods were integrated. An extended PFWZIC was developed, followed by the development of PFDOSM. Results: (1) PFWZIC effectively weighted the vaccine distribution criteria. (2) The PFDOSM-based group prioritisation was considered in the final distribution result. (3) The prioritisation ranks of the vaccine recipients were subject to a systematic ranking that is supported by high correlation results over nine scenarios of the changing criteria weights values. A comparison with previous work also proved the efficiency of the proposed framework. Conclusion: The findings of this study are expected to contribute to ensuring equitable protection against COVID-19 and thus help accelerate vaccine progress worldwide.
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    MRI-negative PET-positive' temporal lobe epilepsy (TLE) and mesial TLE differ with quantitative MRI and PET: a case control study
    Carne, RP ; O'Brien, TJ ; Kilpatrick, CJ ; MacGregor, LR ; Litewka, L ; Hicks, RJ ; Cook, MJ (BMC, 2007-06-24)
    BACKGROUND: 'MRI negative PET positive temporal lobe epilepsy' represents a substantial minority of temporal lobe epilepsy (TLE). Clinicopathological and qualitative imaging differences from mesial temporal lobe epilepsy are reported. We aimed to compare TLE with hippocampal sclerosis (HS+ve) and non lesional TLE without HS (HS-ve) on MRI, with respect to quantitative FDG-PET and MRI measures. METHODS: 30 consecutive HS-ve patients with well-lateralised EEG were compared with 30 age- and sex-matched HS+ve patients with well-lateralised EEG. Cerebral, cortical lobar and hippocampal volumetric and co-registered FDG-PET metabolic analyses were performed. RESULTS: There was no difference in whole brain, cerebral or cerebral cortical volumes. Both groups showed marginally smaller cerebral volumes ipsilateral to epileptogenic side (HS-ve 0.99, p = 0.02, HS+ve 0.98, p < 0.001). In HS+ve, the ratio of epileptogenic cerebrum to whole brain volume was less (p = 0.02); the ratio of epileptogenic cerebral cortex to whole brain in the HS+ve group approached significance (p = 0.06). Relative volume deficits were seen in HS+ve in insular and temporal lobes. Both groups showed marked ipsilateral hypometabolism (p < 0.001), most marked in temporal cortex. Mean hypointensity was more marked in epileptogenic-to-contralateral hippocampus in HS+ve (ratio: 0.86 vs 0.95, p < 0.001). The mean FDG-PET ratio of ipsilateral to contralateral cerebral cortex however was low in both groups (ratio: HS-ve 0.97, p < 0.0001; HS+ve 0.98, p = 0.003), and more marked in HS-ve across all lobes except insula. CONCLUSION: Overall, HS+ve patients showed more hippocampal, but also marginally more ipsilateral cerebral and cerebrocortical atrophy, greater ipsilateral hippocampal hypometabolism but similar ipsilateral cerebral cortical hypometabolism, confirming structural and functional differences between these groups.
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    Tailored Shaping and Time Resampling Functions for Inversion Pulses at 7T
    Hurley, AC ; Coxon, R ; Al-Radaideh, A ; Aickelin, U ; Li, B ; Gowland, P (ISMRM, 2009)
    The RF transmit field is severely inhomogeneous at ultrahigh field, due to both RF penetration and RF coil design issues. Here we utilised a search algorithm to produce inversion pulses tailored to take account of the heterogeneity of the RF transmit field at 7T. We created a slice selective inversion pulse which worked well over the range of RF amplitudes, while maintaining an experimentally achievable pulse length at 7T. The pulses were based on the FOCI technique as well as time dilation of functions but the RF amplitude, frequency sweep and gradient functions were all optimised using a Genetic Algorithm.
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    Artificial Immune Systems: 8th International Conference, ICARIS 2009
    Andrews, P ; Timmis, J ; Owens, N ; Aickelin, U ; al, E ; Andrews, P ; Timmis, J ; Owens, N ; Aickelin, U ; Hart, E ; Hone, A ; Tyrrell, AM (Springer, 2009)
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    The 2007 IEEE Computational Intelligence in Scheduling Symposium(CISsched)
    Abbass, H ; Abdullah, S ; Ahmadi, S ; Aickelin, U ; al, E ; Abbass, H ; Abdullah, S ; Ahmadi, S ; Aikelin, U (IEEE, 2007-04)
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    A Recommender System based on the Immune Network
    Cayzer, S ; Aickelin, U (Hewlett-Packard Company, 2002)
    The immune system is a complex biological system with a highly distributed, adaptive and self-organising nature. This paper presents an artificial immune system (AIS) that exploits some of these characteristics and isapplied to the task of film recommendation by collaborative filtering (CF). Natural evolution and in particular the immune system have not been designed for classical optimisation. However, for this problem, we are not interested in finding a single optimum. Rather we intend to identify a sub-set of good matches on which recommendations can be based. It is our hypothesis that an AIS built on two central aspects of the biological immune system will be an ideal candidate to achieve this: Antigen - antibody interaction for matching and antibody - antibody interaction for diversity. Computational results are presented in support of this conjecture and compared to those found by other CF techniques.
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    A Pyramidal Genetic Algorithm for Multiple-Choice Problems
    Aickelin, U (Operational Research, 2001)