Paediatrics (RCH) - Theses

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Structural and functional evaluation of gas-trapping in infants with cystic fibrosis

Ebdon, Anne-Marie ( 2014)

Air-trapping is frequently identified in infants with cystic fibrosis (CF) on chest CT scans. Aim was to examine the association between the measured functional residual capacity (FRC) using infant lung function under sedation, and air-trapping scores obtained from chest CT images, acquired under general anaesthesia. Thirty-eight lung function tests were analysed from CF infants aged 3-24 months. Twenty CT scans were performed on the infants. No statistical significance was found between the lung function and CT results when simple linear regression was applied. In conclusion, no associations were found between measured FRC and air-trapping CT scores in infants with CF.