Mechanical Engineering - Research Publications
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ItemNo Preview AvailableQuantifying the reduction of airborne infectious viral load using a ventilated patient hood(W B SAUNDERS CO LTD, 2023-06)BACKGROUND: Healthcare workers treating SARS-CoV-2 patients are at risk of infection by respiratory exposure to patient-emitted, virus-laden aerosols. Source control devices such as ventilated patient isolation hoods have been shown to limit the dissemination of non-infectious airborne particles in laboratory tests, but data on their performance in mitigating the airborne transmission risk of infectious viruses are lacking. AIM: We used an infectious airborne virus to quantify the ability of a ventilated hood to reduce infectious virus exposure in indoor environments. METHODS: We nebulized 109 plaque forming units (pfu) of bacteriophage PhiX174 virus into a ∼30-m3 room when the hood was active or inactive. The airborne concentration of infectious virus was measured by BioSpot-VIVAS and settle plates using plaque assay quantification on the bacterial host Escherichia coli C. The airborne particle number concentration (PNC) was also monitored continuously using an optical particle sizer. FINDINGS: The median airborne viral concentration in the room reached 1.41 × 105 pfu/m3 with the hood inactive. When active, the hood reduced infectious virus concentration in air samples by 374-fold. The deposition of infectious virus on the surface of settle plates was reduced by 87-fold. This was associated with a 109-fold reduction in total airborne particle number escape rate. CONCLUSION: A personal ventilation hood significantly reduced airborne particle escape, considerably lowering infectious virus contamination in an indoor environment. Our findings support the further development of source control devices to mitigate nosocomial infection risk among healthcare workers exposed to airborne viruses in clinical settings.
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ItemNo Preview AvailableAerosol generation related to respiratory interventions and the effectiveness of a personal ventilation hood.(College of Intensive Care Medicine of Australia and New Zealand, 2020-09)OBJECTIVE: To quantify aerosol generation from respiratory interventions and the effectiveness of their removal by a personal ventilation hood. DESIGN AND SETTING: Determination of the aerosol particle generation (in a single, healthy volunteer in a clean room) associated with breathing, speaking, wet coughing, oxygen (O2) 15 L/min via face mask, O2 60 L/min via nasal prongs, bilevel non-invasive positive-pressure ventilation (BiPAP) and nebulisation with O2 10 L/min. INTERVENTIONS: Aerosol generation was measured with two particle sizer and counter devices, focusing on aerosols 0.5-5 μm (human-generated aerosols), with and without the hood. An increase from baseline of less than 0.3 particles per mL was considered a low level of generation. MAIN OUTCOME MEASURES: Comparisons of aerosol generation between different respiratory interventions. Effectiveness of aerosol reduction by a personal ventilation hood. RESULTS: Results for the 0.5-5 μm aerosol range. Quiet breathing and talking demonstrated very low increase in aerosols (< 0.1 particles/mL). Aerosol generation was low for wet coughing (0.1 particles/mL), O2 15 L/min via face mask (0.18 particles/mL), and high flow nasal O2 60 L/min (0.24 particles/mL). Non-invasive ventilation generated moderate aerosols (29.7 particles/mL) and nebulisation very high aerosols (1086 particles/mL); the personal ventilation hood reduced the aerosol counts by 98% to 0.5 particles/mL and 8.9 particles/mL respectively. CONCLUSIONS: In this human volunteer study, the administration of O2 15 L/min by face mask and 60 L/min nasal therapy did not increase aerosol generation beyond low levels. Non-invasive ventilation caused moderate aerosol generation and nebulisation therapy very high aerosol generation. The personal ventilation hood reduced the aerosol counts by at least 98%.
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ItemEffectiveness of portable air filtration on reducing indoor aerosol transmission: preclinical observational trials(W B SAUNDERS CO LTD, 2022-01)BACKGROUND: While the range of possible transmission pathways of severe acute respiratory syndrome coronavirus-2 in various settings has been investigated thoroughly, most authorities have recently acknowledged the role of aerosol spread in its transmission, especially in indoor environments where ventilation is poor. Engineering controls are needed to mitigate aerosol transmission in high-risk settings including hospital wards, classrooms and offices. AIM: To assess the effectiveness of aerosol filtration by portable air cleaning devices with high-efficiency particulate air filters used in addition to a standard building heating ventilation and air conditioning (HVAC) system. METHODS: Test rooms, including a single-bed hospital room, were filled with test aerosol to simulate aerosol movement. Aerosol counts were measured over time with various portable air cleaning devices and room ventilation systems to quantify the overall aerosol clearance rate. FINDINGS: Portable air cleaning devices were very effective for removal of aerosols. The aerosols were cleared five times faster in a small control room with portable air cleaning devices than in the room with HVAC alone. The single-bed hospital room had an excellent ventilation rate (∼14 air changes per hour) and cleared the aerosols in 20 min. However, with the addition of two air cleaning devices, the clearance time was three times faster. CONCLUSIONS: Inexpensive portable air cleaning devices should be considered for small and enclosed spaces in healthcare settings, such as inpatient rooms and personal protective equipment donning/doffing stations. Portable air cleaning devices are particularly important where there is limited ability to reduce aerosol transmission with building HVAC ventilation.
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ItemNo Preview AvailableAerosol generation related to respiratory interventions and the effectiveness of a personal ventilation hood.(College of Intensive Care Medicine of Australia and New Zealand, 2020-09)OBJECTIVE: To quantify aerosol generation from respiratory interventions and the effectiveness of their removal by a personal ventilation hood. DESIGN AND SETTING: Determination of the aerosol particle generation (in a single, healthy volunteer in a clean room) associated with breathing, speaking, wet coughing, oxygen (O2) 15 L/min via face mask, O2 60 L/min via nasal prongs, bilevel non-invasive positive-pressure ventilation (BiPAP) and nebulisation with O2 10 L/min. INTERVENTIONS: Aerosol generation was measured with two particle sizer and counter devices, focusing on aerosols 0.5-5 μm (human-generated aerosols), with and without the hood. An increase from baseline of less than 0.3 particles per mL was considered a low level of generation. MAIN OUTCOME MEASURES: Comparisons of aerosol generation between different respiratory interventions. Effectiveness of aerosol reduction by a personal ventilation hood. RESULTS: Results for the 0.5-5 μm aerosol range. Quiet breathing and talking demonstrated very low increase in aerosols (< 0.1 particles/mL). Aerosol generation was low for wet coughing (0.1 particles/mL), O2 15 L/min via face mask (0.18 particles/mL), and high flow nasal O2 60 L/min (0.24 particles/mL). Non-invasive ventilation generated moderate aerosols (29.7 particles/mL) and nebulisation very high aerosols (1086 particles/mL); the personal ventilation hood reduced the aerosol counts by 98% to 0.5 particles/mL and 8.9 particles/mL respectively. CONCLUSIONS: In this human volunteer study, the administration of O2 15 L/min by face mask and 60 L/min nasal therapy did not increase aerosol generation beyond low levels. Non-invasive ventilation caused moderate aerosol generation and nebulisation therapy very high aerosol generation. The personal ventilation hood reduced the aerosol counts by at least 98%.
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ItemTurbulent structures in a statistically three-dimensional boundary layer(Cambridge University Press (CUP), 2019-01-25)We investigate the behaviour of large-scale coherent structures in a spanwise-heterogeneous turbulent boundary layer, using particle image velocimetry on multiple orthogonal planes. The statistical three-dimensionality is imposed by a herringbone riblet surface, although the key results presented here will be common to many cases of wall turbulence with embedded secondary flows in the form of mean streamwise vortices. Instantaneous velocity fields in the logarithmic layer reveal elongated low-momentum streaks located over the upwash-flow region, where their spanwise spacing is forced by the 2δ periodicity of the herringbone pattern. These streaks largely resemble the turbulence structures that occur naturally (and randomly located) in spanwise-homogeneous smooth-/rough-wall boundary layers, although here they are directly formed by the roughness pattern. In the far outer region, the large spanwise spacing permits the streaks to aggressively meander. The mean secondary flows are the time-averaged artefact of the unsteady and spanwise asymmetric large-scale roll modes that accompany these meandering streaks. Interestingly, this meandering, or instability, gives rise to a pronounced streamwise periodicity (i.e. an alternating coherent pattern) in the spatial statistics, at wavelengths of approximately 4.5 δ . Overall, the observed behaviours largely resemble the streak-instability model that has been proposed for the buffer region, only here at a much larger scale and at a forced spanwise spacing. This observation further confirms recent observations that such features may occur at an entire hierarchy of scales throughout the turbulent boundary layer.
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ItemTurbulent flow above wind-generated waves: conditional statistics and POD structures(Australian Fluid Mechanics Society, 2018)Large field-of-view particle image velocimetry (PIV) measurement is performed to characterise the turbulent boundary layer above evolving wind waves, which are developed over 3.5 m fetch at U∞ = 8.2 m/s. This multi-camera experiment captures a streamwise domain of 0.4 m, slightly longer than two dominant wavelength of these wind waves. Instantaneous velocity observations reveal strong flow separations on the leeward side of most dominant waves, and these events are also marked by strong vertical velocity fluctuations. The spatially-averaged velocity profile further indicates a large velocity gradient below the wave crest, which occupies a significant proportion of the boundary layer. The conditionally-averaged flow fields around larger dominant waves show that turbulence stresses are high downwind the wave crest, indicating the highly varying form of the separation events. These events are further elucidated using proper orthogonal decomposition (POD) analysis, where the first few stronger modes reveal several common attributes around the separation events.