Optometry and Vision Sciences - Theses

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Author: Hui, Flora × End date: 2019 × Start date: 2000 × Type: PhD thesis ×

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    Using the eye as a surrogate for the brain: Imaging blood-neural barriers with fluorescein angiography
    Hui, Flora ( 2016)
    The eye allows for direct and non-invasive imaging of the vasculature. Using fluorescein angiography, this thesis explored whether blood vessels in the eye may be a surrogate for those in the brain. The vasculature in both tissues showed similar fluorescence dynamics. Systemic disruption of blood vessel integrity affected both the eye and brain, with effects in the brain lasting longer. Vascular leakage in the eye may provide information about the integrity of the vasculature in the brain.