- School of Social and Political Sciences - Research Publications
School of Social and Political Sciences - Research Publications
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ItemEffects of Progesterone on Mammary Carcinogenesis by DMBA Applied Directly to Rat MammaeJABARA, AG ; MARKS, GN ; SUMMERS, JE ; ANDERSON, PS (Springer Nature, 1979-01-01)The effects and site(s) of action of progesterone on DMBA mammary carcinogenesis in the rat, when a small dose of the carcinogen was applied directly to the inguinal mammary gland, were investigated. No reduction in tumour yield was apparent when progesterone was administered s.c. for 18 days before dusting DMBA. This finding contrasts with a previously reported inhibitory effect on carcinogenesis when hormone treatment was followed by intragastric administration of DMBA. When progesterone injections were begun either 2 days before or 2 days after direct application of DMBA, and were continued until the end of the experiment (135 or 195 days) an enhancement in carcinogenesis was observed similar to that previously demonstrated after gastric intubation of DMBA. These findings, together with previously reported observations, suggest that progesterone may exert its inhibitory effect on carcinogenesis by acting at a site outside the breast, perhaps on the liver. However, it is likely that the hormone acts directly on the mammary tissue to exert its enhancing effect on tumorigenesis.
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ItemNo Preview AvailableThe art tradeCasey, B ; Taylor, P ; Eckstein, J ; Moody, D ; Muir, A ; Shaw, C (Informa UK Limited, 1995-01)
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ItemNo Preview AvailableUtilising older workersTAYLOR, P ; Walker, A (Department of Employment, 1995)
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ItemNo Preview AvailableManaging an Ageing Workforce in Britain and FranceGuillemard, A-M ; Taylor, P ; Walker, A (Springer Science and Business Media LLC, 1996-10)
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ItemNo Preview AvailableAge discrimination and public policyTaylor, P ; Walker, A (MCB UNIV PRESS LTD, 1997)Reviews government and employer policies towards older workers and shows that there has been a massive decline in economic activity among older workers over the last two decades. The major cause is identified as economic recession which has encouraged employers, with the support of government, to target older workers for redundancy. In addition, older workers have been over‐represented in declining industries. Once out in the labour market older workers face considerable age discrimination. Recently, population ageing has encouraged all political parties to revise their policies on age and employment. Each now recognizes the value of older workers, although there is fundamental disagreement about the best means of encouraging employers to change their practices. The then Conservative government favoured a voluntary approach while the Labour Party and the Liberal Democrats have been more favourably disposed towards comprehensive legislation outlawing age discrimination. Argues that a combination of both approaches is desirable and, moreover, that it will also be necessary to revise policies on training, pensions and social security.
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ItemNo Preview AvailableCombatting Age Barriers in Job Recruitment and TrainingTaylor, P ; Walker, A (Informa UK Limited, 1995-03-01)
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ItemNo Preview AvailableCombating Age Discrimination in Employment: Education versus LegislationTaylor, P ; Walker, A (Informa UK Limited, 1995-09-01)
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ItemNo Preview AvailableFactors Associated with Employment Status in Later Working LifeJackson, PR ; Taylor, PE (SAGE Publications, 1994-12-01)
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ItemNo Preview AvailableTHE AGING WORKFORCE - EMPLOYERS ATTITUDES TOWARDS OLDER-PEOPLETAYLOR, PE ; WALKER, A (SAGE PUBLICATIONS LTD, 1994-12)This article reports the results of a national postal survey of employers' attitudes and policies towards older workers supported by the ESRC. The survey's key findings are discussed in the context of the declining labour force participation of older people over the last twenty years and the recent turnaround in official and some employer attitudes towards this group. Findings of particular importance are those relating to the sectoral differences in employers' orientations towards older workers, such as the larger proportion of those in the production and construction than in the service sectors who were using early retirement schemes and the differences in strategic responses to the ageing workforce, with the service sector leading production, construction and manufacturing; the impact of employers' perceptions of older workers' lack of appropriate skills which, when coupled with figures illustrating the lack of access of older people to both official and employer training programmes, suggests a self-fulfilling prophecy; and the surprising support given by employers for anti-age discrimination legislation. Data from the survey are also used to test the model put forward by Atkinson (1989) suggesting that employers' policies develop incrementally. The article concludes by arguing that the educative approach favoured by the government is not likely to have a significant impact on the employment prospects of older workers. Therefore this group is likely to be increasingly confined to a choice between low-skill/low-wage jobs in the service sector or non-employment.