School of Chemistry - Research Publications

Permanent URI for this collection

http://hdl.handle.net/11343/300

Filters

2020 1
1
Reset filters

Settings
Statistics
Citations
Author: Weragoda, Geethika × Author: Forni, Jose Augusto × Start date: 2020 × End date: 2022 ×

Search Results

Now showing 1 - 1 of 1
  • Item
    Thumbnail Image
    Tandem Photoredox Catalysis: Enabling Carbonylative Amidation of Aryl and Alkylhalides
    Forni, JA ; Micic, N ; Connell, TU ; Weragoda, G ; Polyzos, A (WILEY-V C H VERLAG GMBH, 2020-10-12)
    We report a new visible-light-mediated carbonylative amidation of aryl, heteroaryl, and alkyl halides. A tandem catalytic cycle of [Ir(ppy)2 (dtb-bpy)]+ generates a potent iridium photoreductant through a second catalytic cycle in the presence of DIPEA, which productively engages aryl bromides, iodides, and even chlorides as well as primary, secondary, and tertiary alkyl iodides. The versatile in situ generated catalyst is compatible with aliphatic and aromatic amines, shows high functional-group tolerance, and enables the late-stage amidation of complex natural products.