Melbourne School of Psychological Sciences - Research Publications
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ItemDoes prediction error during exposure relate to clinical outcomes in cognitive behavior therapy for social anxiety disorder? A study protocol(FRONTIERS MEDIA SA, 2022-11-24)Facing your fears, or exposure therapy, is an effective psychological intervention for anxiety disorders that is often thought to work through fear extinction learning. Fear extinction learning is a type of associative learning where fear reduces through repeated encounters with a feared situation or stimulus in the absence of aversive outcomes. Laboratory research suggests fear extinction learning is driven by threat prediction errors, defined as when fearful predictions do not eventuate. Threat prediction error and its relationship to exposure therapy outcomes haven't been studied enough in actual therapy settings. It remains unclear whether prediction error and extinction learning are central mechanisms of exposure therapy. We are conducting a longitudinal and observational study of how threat prediction error during exposure in social anxiety disorder (SAD) treatment relates to session-by-session symptom change and treatment outcome in addition to exposure surprise and learning outcome. We aim to recruit 65 adults with a primary diagnosis of SAD through an outpatient psychology clinic. Participants will receive 12 sessions of individual manualized cognitive behavioral therapy (CBT), adapted from an efficacious group protocol, that includes graded exposure. Exposure processes, including self-report measures of anxiety, threat prediction, threat outcomes, surprise, and learning outcome, will be measured with smartphone-based event-contingent ecological momentary assessments (EMAs) of all behavioral experiments completed during treatment. Clinical outcomes include self-reported social anxiety symptoms and social threat appraisals, at each session, post and 3-months after treatment. Prediction error will be operationalized as the mismatch between the threat prediction and threat outcome. The joint effect of threat prediction and threat outcome on session-by-session symptom change, treatment outcome, exposure surprise, and learning outcome will be explored using multilevel modeling. The present study will help determine whether threat prediction error during exposures in SAD treatment is related to theoretically implied clinical outcomes. This would contribute to the larger research aim of clarifying exposure therapy mechanisms.
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ItemInelastic scattering of electrons in water from first principles: cross sections and inelastic mean free path for use in Monte Carlo track-structure simulations of biological damage(ROYAL SOC, 2022-05-18)Modelling the inelastic scattering of electrons in water is fundamental, given their crucial role in biological damage. In Monte Carlo track-structure (MC-TS) codes used to assess biological damage, the energy loss function (ELF), from which cross sections are extracted, is derived from different semi-empirical optical models. Only recently have first ab initio results for the ELF and cross sections in water become available. For benchmarking purpose, in this work, we present ab initio linear-response time-dependent density functional theory calculations of the ELF of liquid water. We calculated the inelastic scattering cross sections, inelastic mean free paths, and electronic stopping power and compared our results with recent calculations and experimental data showing a good agreement. In addition, we provide an in-depth analysis of the contributions of different molecular orbitals, species and orbital angular momenta to the total ELF. Moreover, we present single-differential cross sections computed for each molecular orbital channel, which should prove useful for MC-TS simulations.
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ItemNo Preview AvailableNegative Emotion and Nonacceptance of Emotion in Daily Life(AMER PSYCHOLOGICAL ASSOC, 2022-08)Nonacceptance of emotion is consistently linked with increased levels of psychopathology and diminished well-being. Research has found that negative emotion and nonacceptance of emotion are positively associated cross-sectionally but has yet to directly investigate temporal associations between these constructs. Given that negative emotions are frequently the target of negative thoughts and other emotions, and that acceptance of emotion is associated with prospective decreases in negative emotion, we hypothesized that the temporal relation between negative emotion and nonacceptance of emotion is bidirectional. The present study examined the association between these variables during people's daily lives using an experience sampling methodology. Multilevel modeling was used for all analyses, including hierarchical generalized linear modeling and log-normal hurdle modeling. A total of 187 women from the United States and Australia reported negative emotion and nonacceptance of emotion 14 times a day for 5 days. Negative emotion and nonacceptance of emotion were positively associated contemporaneously. Across time, nonacceptance of emotion was prospectively and positively associated with the intensity of negative emotion independent of immediately prior negative emotion, and negative emotion intensity was prospectively and positively associated with nonacceptance of emotion independent of immediately prior nonacceptance. Results support a bidirectional model of negative emotion and nonacceptance of emotion wherein each variable predicts increases in the other across time. Our findings elucidate how individuals fall into maladaptive emotional patterns that are difficult to break and could possibly pave the way to the development and maintenance of psychopathology. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
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ItemNo Preview AvailableSome Recommendations on the Use of Daily Life Methods in Affective Science(SPRINGERNATURE, 2022-06)Real-world emotions are often more vivid, personally meaningful, and consequential than those evoked in the lab. Therefore, studying emotions in daily life is essential to test theories, discover new phenomena, and understand healthy emotional functioning; in short, to move affective science forward. The past decades have seen a surge of research using daily diary, experience sampling, or ecological momentary assessment methods to study emotional phenomena in daily life. In this paper, we will share some of the insights we have gained from our collective experience applying such daily life methods to study everyday affective processes. We highlight what we see as important considerations and caveats involved in using these methods and formulate recommendations to improve their use in future research. These insights focus on the importance of (i) theory and hypothesis-testing; (ii) measurement; (iii) timescale; and (iv) context, when studying emotions in their natural habitat.
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ItemBlinded by and Stuck in Negative Emotions: Is Psychological Inflexibility Across Different Domains Related?(SPRINGERNATURE, 2022-12)UNLABELLED: Psychological inflexibility is theorized to underlie difficulties adjusting mental processes in response to changing circumstances. People show inflexibility across a range of domains, including attention, cognition, and affect. But it remains unclear whether common mechanisms underlie inflexibility in different domains. We investigated this possibility in a pre-registered replication and extension examining associations among attentional, cognitive, and affective inflexibility measures. Participants (N = 196) completed lab tasks assessing (a) emotion-induced blindness, the tendency for task-irrelevant emotional stimuli to impair attention allocation to non-emotional stimuli; (b) emotional inertia, the tendency for feelings to persist across time and contexts; and global self-report measures of (c) repetitive negative thinking, the tendency to repeatedly engage in negative self-focused thoughts (i.e., rumination, worry). Based on prior research linking repetitive negative thinking with negative affect inertia, on one hand, and emotion-induced blindness, on the other, we predicted positive correlations among all three measures of inflexibility. However, none of the three measures were related and Bayes factors indicated strong evidence for independence. Supplementary analyses ruled out alternative explanations for our findings, e.g., analytic decisions. Although our findings question the overlap between attentional, cognitive, and affective inflexibility measures, this study has methodological limitations. For instance, our measures varied across more than their inflexibility domain and our sample, relative to previous studies, included a high proportion of Asian participants who may show different patterns of ruminative thinking to non-Asian participants. Future research should address these limitations to confirm that common mechanisms do not underlie attentional, cognitive, and affective inflexibility. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s42761-022-00145-2.
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ItemSocial Support Predicts Differential Use, but not Differential Effectiveness, of Expressive Suppression and Social Sharing in Daily Life(SPRINGERNATURE, 2022-09)UNLABELLED: While emotion regulation often happens in the presence of others, little is known about how social context shapes regulatory efforts and outcomes. One key element of the social context is social support. In two experience sampling studies (Ns = 179 and 123), we examined how the use and affective consequences of two fundamentally social emotion-regulation strategies-social sharing and expressive suppression-vary as a function of perceived social support. Across both studies, we found evidence that social support was associated with variation in people's use of these strategies, such that when people perceived their environments as being higher (vs. lower) in social support, they engaged in more sharing and less suppression. However, we found only limited and inconsistent support for context-dependent affective outcomes of suppression and sharing: suppression was associated with better affective consequences in the context of higher perceived social support in Study 1, but this effect did not replicate in Study 2. Taken together, these findings suggest that the use of social emotion-regulation strategies may depend on contextual variability in social support, whereas their effectiveness does not. Future research is needed to better understand the circumstances in which context-dependent use of emotion regulation may have emotional benefits, accounting for personal, situational, and cultural factors. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s42761-022-00123-8.
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ItemNo Preview AvailableModeling Individual Differences in Emotion Regulation Repertoire in Daily Life With Multilevel Latent Profile Analysis(AMER PSYCHOLOGICAL ASSOC, 2020-12)Emotion regulation (ER) repertoire-the range of different ER strategies an individual utilizes across situations-is assumed to enable more adaptive ER and greater well-being. ER repertoire has been operationalized by a quantitative index (sum of ER strategies across situations) or by applying a person-centered approach to global self-reports of dispositional ER. We aimed to assess ER repertoire in daily life by using an experience sampling methodology (ESM) and a person-centered approach that could account for nested data. We used multilevel latent profile analyses of ESM data (N = 179, 9-10 prompts per day over 21 days) to (a) group the occasions into latent profiles of momentary ER strategies, (b) group individuals whose distributions of ER profiles differed across occasions into latent classes, and (c) examine well-being correlates of class membership at the person level. At the occasion level, we identified nine ER profiles that differed in degree of use (e.g., no use of any vs. strong use of all strategies) and in specific combinations of strategies (e.g., situation selection and acceptance vs. suppression and ignoring). At the person level, we identified 5 classes of individuals differing in the degree to which they used various momentary ER profiles versus one predominant profile across situations. Well-being was highest for individuals who used multiple ER profiles of active strategies and lowest for individuals who used ER profiles focused on suppression. Hence, both ER repertoire width and the specific make-up of the ER repertoire were relevant for the relation between ER repertoire and well-being. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
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ItemA pilot trial of moderated online social therapy for family and friends of young people with borderline personality disorder features(WILEY, 2021-12)AIM: We evaluated the acceptability, usability and safety of Kindred, a novel online intervention for carers of young people with borderline personality disorder (BPD) using a pre-post pilot trial design. The secondary aim explored whether Kindred use was associated with clinical improvements for caregivers on measures of burden of caregiving, stress, expressed emotion, family communication, disability, coping and knowledge of BPD and for patients on measures of severity of BPD symptoms and level of functional impairment. METHODS: The trial site was the Helping Young People Early program for young people with BPD at Orygen in Melbourne, Australia. Informed consent was obtained from 20 adult carers (i.e., relatives or friends) and 10 young people aged 15-25 with BPD. Kindred, which was available for 3 months, incorporated online psychoeducation, carer-to-carer social networking and guidance from expert and peer moderators. Assessments were completed at baseline and 3 months follow-up. Multiple indicators of acceptability, usability and safety were utilized. RESULTS: Seventeen carers were enrolled in Kindred and eight young people completed baseline measures. A priori acceptability, usability and safety criteria were met. Carer burden, stress, expressed emotion, family communication, quality of life, functioning, coping and perceived knowledge of BPD improved at follow-up. Sixty-six percent of the young people (4/6) reported that they believed Kindred had improved their carers' understanding of BPD. CONCLUSION: Kindred was shown to be acceptable, usable and safe, with encouraging improvements in both carer and young person outcomes. Kindred warrants evaluation of its efficacy via an randomized controlled trial.
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ItemPositive and meaningful lives: Systematic review and meta-analysis of eudaimonic well-being in first-episode psychosis(WILEY, 2021-10)BACKGROUND: First-episode psychosis typically has its onset during adolescence. Prolonged deficits in social functioning are common in FEP and yet often variance in functioning remains unexplained. Developmental psychology frameworks may be useful for understanding these deficits. Eudaimonic well-being (EWB), or positive self-development, is a developmental psychology construct that has been shown to predict mental health outcomes across multiple populations but has not been systematically reviewed in FEP. AIM: Our aim was to systematically review the evidence for: the predictors of EWB, the effectiveness of EWB interventions and to examine the quality of this research in FEP. METHODS: Selected studies measured either composite or components of EWB. A systematic search produced 2876 abstracts and 122 articles were identified for full screening which produced 17 final papers with 2459 participants. RESULTS: Studies comprised six RCTs, eight prospective follow-up studies and three case-controlled studies. Self-esteem and self-efficacy were the most commonly measured components. A meta-analysis of RCTs revealed no statistically significant effect of interventions on self-esteem. The extant research indicates that character strengths may be associated with higher EWB. Self-esteem may be lower in FEP compared with age matched controls but not different from ultra-high risk patients. Self-esteem appears to be associated with poorer insight and improved therapeutic alliance. Significant problems with both external and internal validity of reviewed studies were apparent. CONCLUSIONS: The hypotheses that lowered EWB is a risk factor for both onset of FEP and for poorer functional outcomes warrant further investigation. There is currently no evidence for effective interventions for EWB in FEP.