Melbourne School of Psychological Sciences - Research Publications
Permanent URI for this collection
Search Results
1 - 10 of 20
-
ItemCognitive and academic outcome following cranial irradiation and chemotherapy in children: a longitudinal study.(Springer Science and Business Media LLC, 2000-01)Cranial irradiation therapy (CRT) and chemotherapy are associated with neurobehavioural deficits. Many studies have investigated late effects of these treatments, but few have evaluated changes in abilities over time. This study employed a longitudinal design to map abilities following these treatments. Three groups of children were studied: Group 1 (n = 35): children treated with CRT (18 Gy) + chemotherapy, aged 5 years or less at time of diagnosis; Group 2 (n = 19): children treated with chemotherapy alone, aged 5 years or less at time of diagnosis; Group 3 (n = 35): healthy children. All children were aged 7-13 years at time of initial assessment, with no pre-diagnosis history of neurologic, developmental, or psychiatric disorder. Intellectual and educational abilities were evaluated twice: T1, not less than 2 years post-treatment, and T2, 3 years later. Group 1 achieved poorest results at T1, with comparison groups performing similarly. At T2 group differences were maintained. For verbal skills differences remained stable. Group 1 exhibited deterioration on non-verbal and processing tasks, while comparison groups showed improved abilities. Group 1 exhibited increases in literacy skills, with educational intervention predicting progress. Results suggest cumulative deficits in non-verbal and information processing skills for children treated with CRT + chemotherapy, with other deficits remaining relatively stable over time. Improved literacy skills suggest that gains can occur with remediation.
-
ItemRisk factors for intellectual and educational sequelae of cranial irradiation in childhood acute lymphoblastic leukaemia.(Springer Science and Business Media LLC, 1996-03)Long-term cognitive and educational sequelae have been inconsistently reported in children who received cranial irradiation (CRT) to prevent central nervous system (CNS) disease in acute lymphoblastic leukaemia (ALL). This study investigates a large and representative sample of survivors of ALL and compares them with non-irradiated survivors of cancer and healthy control children to determine the effect of CRT on cognitive and educational ability. Three groups of children were studied: Group 1 (n=100) survivors of ALL treated with chemotherapy and CRT, group 2 (n=50) children with a variety of malignancies treated with chemotherapy alone, group 3(n=100) healthy children. Cognitive and educational abilities of these groups were evaluated using standardised psychometric techniques. Significant differences in cognitive and educational abilities were found between the children in group 1 (chemotherapy + CRT) and the two control groups, with the children receiving CRT performing less well in a range of tests. Greatest differences were detected for tasks dependent on language function including verbal IQ, reading and spelling. Within group 1 a younger age at treatment (less than 5 years) and a higher dose of CRT (24 Gy vs 18 Gy) were predictive of poor long-term outcome for cognitive and education ability. In contrast, children who received chemotherapy alone, with or without intrathecal methotrexate, performed similarly to healthy controls. No gender differences were detected for these measures.
-
ItemNo Preview AvailableImpact of ostracism on social judgments and decisions: Explicit and Implicit Responses(Cambridge University Press, 2003)
-
ItemNo Preview AvailableInvestigations into differences between social- and cyberostracism(American Psychological Association (APA), 2002-01-01)
-
ItemNo Preview AvailablePainting preference and personality, with particular reference to Gray's behavioral inhibition and behavioral approach systems(Baywood Publishing Company, 2002)
-
ItemNo Preview AvailableChronic Illness Peer Support (ChIPS)(Royal Australian College of General, 1997)
-
ItemDevelopment of the Teenage Cancer Peer Support Program, CanTeen.(Australian Clearinghouse for Youth Studies, 1997)
-
ItemNo Preview AvailableChronic Illness Peer Support: Assisting young people adjust to life with a chronic illness(The Australian Council for Educational Research, Albany Press, 1996)
-
ItemNo Preview AvailableThe Chronic Illness Peer Support Program(Health Issues Centre, 1996)
-
ItemNo Preview AvailableChronic Illness Peer Support (ChIPS): Assisting adolescent adjustment to life with a chronic illness.(Health Education Association of VIctoria, 1995)