Surgery (RMH) - Research Publications

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Type: Journal Article × Start date: 2008 × End date: 2009 × Author: Murphy, Declan ×

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    Abstracts of 4th World Robotic Urology Symposium, Orlando, Florida, 6-8 April 2009.
    Murphy, DG ; Challacombe, B ; COSTELLO, A (Springer Science and Business Media LLC, 2009-06)
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    Robotic assisted radical prostatectomy in older men
    Challacombe, B ; Kyle, C ; Bradford, T ; Murphy, D ; Peters, J ; Kerger, M ; COSTELLO, A ( 2009)
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    Salvage robotic-assisted laparoscopic radical prostatectomy following failed primary high-intensity focussed ultrasound treatment for localised prostate cancer.
    Murphy, DG ; Pedersen, J ; Costello, AJ (Springer Science and Business Media LLC, 2008-09)
    We report the first case of salvage robotic-assisted laparoscopic radical prostatectomy (RALP) following failed primary high-intensity focussed ultrasound (HIFU) for localised carcinoma of the prostate. A 66-year-old male with a presenting prostate-specific antigen (PSA) of 5 ng/ml was diagnosed with T1c Gleason 3 + 4 prostate cancer. He underwent transurethral resection of the prostate and HIFU. His PSA dropped to 2.0 ng/ml and repeat biopsy revealed upgrading of his prostate cancer to Gleason 4 + 3. He was referred to us for a second opinion and, following discussion of his options, he underwent RALP. The total operative time was 159 min. There were no intra- or postoperative complications. He was discharged on postoperative day two and was fully continent 10 days following removal of his catheter. His PSA remained undetectable 6 months postoperatively. Salvage RALP was feasible in this case with good functional and short-term oncological outcomes for the patient.
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    High prostatic fascia release or standard nerve sparing? A viewpoint from the Royal Melbourne Hospital
    Murphy, DG ; Costello, AJ (SPRINGER LONDON LTD, 2008-09-01)
    Radical prostatectomy with preservation of the neurovascular bundles (NVB) is a treatment option for localised prostate cancer in selected patients. An interesting debate has developed about the precise technique used to preserve these nerves. The standard technique releases the NVB from the postero-lateral groove between the prostate and rectum. A new technique, dubbed the "veil of Aphrodite" technique, proposes a higher release of the lateral prostatic fascia on the presumption that cavernosal nerves exist in this area. We have reviewed the evidence for the anatomical basis of nerve-sparing radical prostatectomy, particularly with respect to the standard versus the "veil" technique of radical prostatectomy. Microdissections of the NVB in cadaveric specimens have confirmed the course of the cavernosal nerves in the postero-lateral groove between the prostate and rectum. Though studies have also demonstrated nerves higher in the lateral prostatic fascia, these are likely to innervate the prostate rather than the cavernosal tissues. Though excellent potency results have been reported for the "veil" technique from one institution, there is not sufficient anatomical evidence to support this technique over the standard technique of nerve-sparing radical prostatectomy.