Melbourne University Sport - Research Publications

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    Integrating acute stroke telemedicine consultations into specialists' usual practice: a qualitative analysis comparing the experience of Australia and the United Kingdom
    Bagot, KL ; Cadilhac, DA ; Bladin, CF ; Watkins, CL ; Vu, M ; Donnan, GA ; Dewey, HM ; Emsley, HCA ; Davies, DP ; Day, E ; Ford, GA ; Price, CI ; May, CR ; McLoughlin, ASR ; Gibson, JME ; Lightbody, CE (BMC, 2017-11-21)
    BACKGROUND: Stroke telemedicine can reduce healthcare inequities by increasing access to specialists. Successful telemedicine networks require specialists adapting clinical practice to provide remote consultations. Variation in experiences of specialists between different countries is unknown. To support future implementation, we compared perceptions of Australian and United Kingdom specialists providing remote acute stroke consultations. METHODS: Specialist participants were identified using purposive sampling from two new services: Australia's Victorian Stroke Telemedicine Program (n = 6; 2010-13) and the United Kingdom's Cumbria and Lancashire telestroke network (n = 5; 2010-2012). Semi-structured interviews were conducted pre- and post-implementation, recorded and transcribed verbatim. Deductive thematic and content analysis (NVivo) was undertaken by two independent coders using Normalisation Process Theory to explore integration of telemedicine into practice. Agreement between coders was M = 91%, SD = 9 and weighted average κ = 0.70. RESULTS: Cross-cultural similarities and differences were found. In both countries, specialists described old and new consulting practices, the purpose and value of telemedicine systems, and concerns regarding confidence in the assessment and diagnostic skills of unknown colleagues requesting telemedicine support. Australian specialists discussed how remote consultations impacted on usual roles and suggested future improvements, while United Kingdom specialists discussed system governance, policy and procedures. CONCLUSION: Australian and United Kingdom specialists reported telemedicine required changes in work practice and development of new skills. Both groups described potential for improvements in stroke telemedicine systems with Australian specialists more focused on role change and the United Kingdom on system governance issues. Future research should examine if cross-cultural variation reflects different models of care and extends to other networks.
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    Restrictive versus liberal fluid therapy in major abdominal surgery (RELIEF): rationale and design for a multicentre randomised trial
    Myles, P ; Bellomo, R ; Corcoran, T ; Forbes, A ; Wallace, S ; Peyton, P ; Christophi, C ; Story, D ; Leslie, K ; Serpell, J ; McGuinness, S ; Parke, R (BMJ PUBLISHING GROUP, 2017-03)
    INTRODUCTION: The optimal intravenous fluid regimen for patients undergoing major abdominal surgery is unclear. However, results from many small studies suggest a restrictive regimen may lead to better outcomes. A large, definitive clinical trial evaluating perioperative fluid replacement in major abdominal surgery, therefore, is required. METHODS/ANALYSIS: We designed a pragmatic, multicentre, randomised, controlled trial (the RELIEF trial). A total of 3000 patients were enrolled in this study and randomly allocated to a restrictive or liberal fluid regimen in a 1:1 ratio, stratified by centre and planned critical care admission. The expected fluid volumes in the first 24 hour from the start of surgery in restrictive and liberal groups were ≤3.0 L and ≥5.4 L, respectively. Patient enrolment is complete, and follow-up for the primary end point is ongoing. The primary outcome is disability-free survival at 1 year after surgery, with disability defined as a persistent (at least 6 months) reduction in functional status using the 12-item version of the World Health Organisation Disability Assessment Schedule. ETHICS/DISSEMINATION: The RELIEF trial has been approved by the responsible ethics committees of all participating sites. Participant recruitment began in March 2013 and was completed in August 2016, and 1-year follow-up will conclude in August 2017. Publication of the results of the RELIEF trial is anticipated in early 2018. TRIAL REGISTRATION NUMBER: ClinicalTrials.gov identifier NCT01424150.
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    Global optimisation of chiller sequencing and load balancing using Shuffled Complex Evolution
    Stewart, I ; Aye, L ; Peterson, T (International Building Performance Simulation Association & AIRAH, 2017-11-15)
    A new model has been developed to optimise the sequencing and load balancing of chillers in the central plants of commercial buildings with multiple water-cooled chillers. The model uses the Shuffled Complex Evolution optmisation algorithm to minimise the total energy consumptions of chillers and pumps by maximising the whole system (central plant) coefficient of performance under a known discrete cooling load. Two commercial buildings in Melbourne’s CBD were simulated as case studies to assess the validity and effectiveness of the model. The control strategies identified by the model performed better than the existing configuration in both cases, reducing energy consumption by 12.2% and 16.6% when compared to the observed energy data for 2016.