School of Physics - Research Publications

Permanent URI for this collection

Search Results

Now showing 1 - 10 of 1995
  • Item
    Thumbnail Image
    Nanoparticle-based optical interfaces for retinal neuromodulation: a review.
    Stoddart, PR ; Begeng, JM ; Tong, W ; Ibbotson, MR ; Kameneva, T (Frontiers Media SA, 2024)
    Degeneration of photoreceptors in the retina is a leading cause of blindness, but commonly leaves the retinal ganglion cells (RGCs) and/or bipolar cells extant. Consequently, these cells are an attractive target for the invasive electrical implants colloquially known as "bionic eyes." However, after more than two decades of concerted effort, interfaces based on conventional electrical stimulation approaches have delivered limited efficacy, primarily due to the current spread in retinal tissue, which precludes high-acuity vision. The ideal prosthetic solution would be less invasive, provide single-cell resolution and an ability to differentiate between different cell types. Nanoparticle-mediated approaches can address some of these requirements, with particular attention being directed at light-sensitive nanoparticles that can be accessed via the intrinsic optics of the eye. Here we survey the available known nanoparticle-based optical transduction mechanisms that can be exploited for neuromodulation. We review the rapid progress in the field, together with outstanding challenges that must be addressed to translate these techniques to clinical practice. In particular, successful translation will likely require efficient delivery of nanoparticles to stable and precisely defined locations in the retinal tissues. Therefore, we also emphasize the current literature relating to the pharmacokinetics of nanoparticles in the eye. While considerable challenges remain to be overcome, progress to date shows great potential for nanoparticle-based interfaces to revolutionize the field of visual prostheses.
  • Item
    Thumbnail Image
    A scalable and fast artificial neural network syndrome decoder for surface codes
    Gicev, S ; Hollenberg, LCL ; Usman, M (VEREIN FORDERUNG OPEN ACCESS PUBLIZIERENS QUANTENWISSENSCHAF, 2023-07-12)
    Surface code error correction offers a highly promising pathway to achieve scalable fault-tolerant quantum computing. When operated as stabilizer codes, surface code computations consist of a syndrome decoding step where measured stabilizer operators are used to determine appropriate corrections for errors in physical qubits. Decoding algorithms have undergone substantial development, with recent work incorporating machine learning (ML) techniques. Despite promising initial results, the ML-based syndrome decoders are still limited to small scale demonstrations with low latency and are incapable of handling surface codes with boundary conditions and various shapes needed for lattice surgery and braiding. Here, we report the development of an artificial neural network (ANN) based scalable and fast syndrome decoder capable of decoding surface codes of arbitrary shape and size with data qubits suffering from the depolarizing error model. Based on rigorous training over 50 million random quantum error instances, our ANN decoder is shown to work with code distances exceeding 1000 (more than 4 million physical qubits), which is the largest ML-based decoder demonstration to-date. The established ANN decoder demonstrates an execution time in principle independent of code distance, implying that its implementation on dedicated hardware could potentially offer surface code decoding times of O(μsec), commensurate with the experimentally realisable qubit coherence times. With the anticipated scale-up of quantum processors within the next decade, their augmentation with a fast and scalable syndrome decoder such as developed in our work is expected to play a decisive role towards experimental implementation of fault-tolerant quantum information processing.
  • Item
    Thumbnail Image
    Improved Placement Precision of Donor Spin Qubits in Silicon using Molecule Ion Implantation
    Holmes, D ; Wilhelm, B ; Jakob, AM ; Yu, X ; Hudson, FE ; Itoh, KM ; Dzurak, AS ; Jamieson, DN ; Morello, A (WILEY, 2024-03)
    Abstract Donor spins in silicon‐28 are among the best performing qubits in the solid state, offering unmatched coherence times, gate fidelities beyond 99% and the ability to fabricate arrays using deterministic ion implantation. Donor placement precision is improved upon, advantageous for qubit readout and coupling, by implanting molecule ions that carry bystander atoms to boost the detection confidence. Here, the suitability of phosphorus difluoride () molecule ions is demonstrated to fabricate donor qubits. Using secondary ion mass spectrometry, it is confirmed that (nuclear spin ) diffuses away from the implant site while remains close to its original location during a donor activation anneal. Electron spin resonance measurements are then performed on ‐implanted qubit devices. A pure dephasing time of and a coherence time of are extracted for the P donor electron‐ values comparable to those found in conventional atomic ‐implanted qubit devices. Additionally, the P donor electron is not found to hyperfine couple to any nuclear spins in its vicinity. Molecule ions therefore show great promise for producing high‐precision deterministically‐implanted arrays of long‐lived donor spin qubits.
  • Item
    Thumbnail Image
    Photo-Induced Charge State Dynamics of the Neutral and Negatively Charged Silicon Vacancy Centers in Room-Temperature Diamond.
    Garcia-Arellano, G ; López-Morales, GI ; Manson, NB ; Flick, J ; Wood, AA ; Meriles, CA (Wiley, 2024-03-12)
    The silicon vacancy (SiV) center in diamond is drawing much attention due to its optical and spin properties, attractive for quantum information processing and sensing. Comparatively little is known, however, about the dynamics governing SiV charge state interconversion mainly due to challenges associated with generating, stabilizing, and characterizing all possible charge states, particularly at room temperature. Here, multi-color confocal microscopy and density functional theory are used to examine photo-induced SiV recombination - from neutral, to single-, to double-negatively charged - over a broad spectral window in chemical-vapor-deposition (CVD) diamond under ambient conditions. For the SiV0 to SiV- transition, a linear growth of the photo-recombination rate with laser power at all observed wavelengths is found, a hallmark of single photon dynamics. Laser excitation of SiV- , on the other hand, yields only fractional recombination into SiV2- , a finding that is interpreted in terms of a photo-activated electron tunneling process from proximal nitrogen atoms.
  • Item
    Thumbnail Image
    Early Results from GLASS-JWST. XXIV. The Mass-Metallicity Relation in Lensed Field Galaxies at Cosmic Noon with NIRISS
    He, X ; Wang, X ; Jones, T ; Treu, T ; Glazebrook, K ; Malkan, MA ; Vulcani, B ; Metha, B ; Bradac, M ; Brammer, G ; Roberts-Borsani, G ; Strait, V ; Bonchi, A ; Castellano, M ; Fontana, A ; Mason, C ; Merlin, E ; Morishita, T ; Paris, D ; Santini, P ; Trenti, M ; Boyett, K ; Grasha, K (IOP Publishing Ltd, 2024-01-01)
    Abstract We present a measurement of the mass–metallicity relation (MZR) at Cosmic Noon, using the JWST near-infrared wide-field slitless spectroscopy obtained by the GLASS-JWST Early Release Science program. By combining the power of JWST and the lensing magnification by the foreground cluster A2744, we extend the measurements of the MZR to the dwarf mass regime at high redshifts. A sample of 50 galaxies with several emission lines is identified across two wide redshift ranges of z = 1.8–2.3 and 2.6–3.4 in the stellar mass range of log ( M * / M ⊙ ) ∈ [ 6.9 , 10.0 ] . The observed slope of MZR is 0.223 ± 0.017 and 0.294 ± 0.010 at these two redshift ranges, respectively, consistent with the slopes measured in field galaxies with higher masses. In addition, we assess the impact of the morphological broadening on emission line measurement by comparing two methods of using 2D forward modeling and line profile fitting to 1D extracted spectra. We show that ignoring the morphological broadening effect when deriving line fluxes from grism spectra results in a systematic reduction of flux by ∼30% on average. This discrepancy appears to affect all the lines and thus does not lead to significant changes in flux ratio and metallicity measurements. This assessment of the morphological broadening effect using JWST data presents, for the first time, an important guideline for future work deriving galaxy line fluxes from wide-field slitless spectroscopy, such as Euclid, Roman, and the Chinese Space Station Telescope.
  • Item
    Thumbnail Image
    JADES: Resolving the Stellar Component and Filamentary Overdense Environment of Hubble Space Telescope (HST)-dark Submillimeter Galaxy HDF850.1 at z=5.18
    Sun, F ; Helton, JM ; Egami, E ; Hainline, KN ; Rieke, GH ; Willmer, CNA ; Eisenstein, DJ ; Johnson, BD ; Rieke, MJ ; Robertson, B ; Tacchella, S ; Alberts, S ; Baker, WM ; Bhatawdekar, R ; Boyett, K ; Bunker, AJ ; Charlot, S ; Chen, Z ; Chevallard, J ; Curtis-Lake, E ; Danhaive, AL ; Decoursey, C ; Ji, Z ; Lyu, J ; Maiolino, R ; Rujopakarn, W ; Sandles, L ; Shivaei, I ; Uebler, H ; Willott, C ; Witstok, J (IOP Publishing Ltd, 2024-01-01)
    Abstract HDF850.1 is the brightest submillimeter galaxy (SMG) in the Hubble Deep Field. It is known as a heavily dust-obscured star-forming galaxy embedded in an overdense environment at z = 5.18. With nine-band NIRCam images at 0.8–5.0 μm obtained through the JWST Advanced Deep Extragalactic Survey, we detect and resolve the rest-frame UV–optical counterpart of HDF850.1, which splits into two components because of heavy dust obscuration in the center. The southern component leaks UV and Hα photons, bringing the galaxy ∼100 times above the empirical relation between infrared excess and UV continuum slope (IRX–β UV). The northern component is higher in dust attenuation and thus fainter in UV and Hα surface brightness. We construct a spatially resolved dust-attenuation map from the NIRCam images, well matched with the dust continuum emission obtained through millimeter interferometry. The whole system hosts a stellar mass of 1010.8±0.1 M ⊙ and star formation rate (SFR) of 102.8±0.2 M ⊙ yr−1, placing the galaxy at the massive end of the star-forming main sequence at this epoch. We further confirm that HDF850.1 resides in a complex overdense environment at z = 5.17–5.30, which hosts another luminous SMG at z = 5.30 (GN10). The filamentary structures of the overdensity are characterized by 109 Hα-emitting galaxies confirmed through NIRCam slitless spectroscopy at 3.9–5 μm, of which only eight were known before the JWST observations. Given the existence of a similar galaxy overdensity in the GOODS-S field, our results suggest that 50% ± 20% of the cosmic star formation at z = 5.1–5.5 occur in protocluster environments.
  • Item
    Thumbnail Image
    Dark-ages reionization and galaxy formation simulation - XXI. Constraining the evolution of the ionizing escape fraction
    Mutch, SJ ; Greig, B ; Qin, Y ; Poole, GB ; Wyithe, JSB (OXFORD UNIV PRESS, 2024-01)
    ABSTRACT The fraction of ionizing photons that escape their host galaxies to ionize hydrogen in the intergalactic medium (IGM) is a critical parameter in analyses of the reionization era. In this paper, we use the meraxes semi-analytic galaxy formation model to infer the mean ionizing photon escape fraction and its dependence on galaxy properties through joint modelling of the observed high redshift galaxy population and existing constraints on the reionization history. Using a Bayesian framework, and under the assumption that escape fraction is primarily related to halo mass, we find that the joint constraints of the ultraviolet luminosity function, cosmic microwave background optical depth, and the Ly α forest require an escape fraction of $(18\pm 5)$ per cent for galaxies within haloes of M ≲ 109 M⊙ and $(5\pm 2)$ per cent for more massive haloes. In terms of galaxy properties, this transition in escape fraction occurs at stellar masses of M⋆ ∼ 107 M⊙, nearly independent of redshift. As a function of redshift, reionization is dominated by the smaller M⋆ ≲ 107 M⊙ galaxies with high escape fractions at z ≳ 6 and by the larger M⋆ ≳ 107 M⊙ galaxies with lower escape fractions at z ≲ 6. Galaxies with star formation rates of 10−2.5 M⊙yr−1 to 10−1.5 M⊙yr−1 provide the dominant source of ionizing photons throughout reionization. Our results are consistent with recent direct measurements of a $\sim 5~{{\ \rm per\ cent}}$ escape fraction from massive galaxies at the end of reionization and support the picture of low mass galaxies being the dominant sources of ionizing photons during reionization.
  • Item
    Thumbnail Image
    Fisher matrix forecasts on the astrophysics of galaxies during the epoch of reionization from the 21-cm power spectra
    Balu, S ; Greig, B ; Wyithe, JSB (OXFORD UNIV PRESS, 2023-10)
    ABSTRACT The hyperfine 21-cm transition of neutral hydrogen from the early Universe (z > 5) is a sensitive probe of the formation and evolution of the first luminous sources. Using the Fisher matrix formalism we explore the complex and degenerate high-dimensional parameter space associated with the high-z sources of this era and forecast quantitative constraints from a future 21-cm power spectrum (21-cm PS) detection. This is achieved using $\rm {\small ERAXES}$, a coupled semi-analytic galaxy formation model and reionization simulation, applied to an N-body halo merger tree with a statistically complete population of all atomically cooled galaxies out to z ∼ 20. Our mock observation assumes a 21-cm detection spanning z ∈ [5, 24] from a 1000 h mock observation with the forthcoming Square Kilometre Array, and is calibrated with respect to ultraviolet luminosity functions (UV LFs) at z ∈ [5, 10], the optical depth of CMB photons to Thompson scattering from Planck, and various constraints on the IGM neutral fraction at z > 5. In this work, we focus on the X-ray luminosity, ionizing UV photon escape fraction, star formation, and supernova feedback of the first galaxies. We demonstrate that it is possible to recover five of the eight parameters describing these properties with better than 50 per cent precision using just the 21-cm PS. By combining with UV LFs, we are able to improve our forecast, with five of the eight parameters constrained to better than 10 per cent (and all below 50 per cent).
  • Item
    Thumbnail Image
    Magnetically confined mountains on accreting neutron stars in general relativity
    Rossetto, PHB ; Frauendiener, J ; Brunet, R ; Melatos, A (OXFORD UNIV PRESS, 2023-09-29)
    ABSTRACT The general relativistic formulation of the problem of magnetically confined mountains on neutron stars is presented, and the resulting equations are solved numerically, generalizing previous Newtonian calculations. The hydromagnetic structure of the accreted matter and the subsequent magnetic burial of the star’s magnetic dipole moment are computed. Overall, it is observed that relativistic corrections reduce the hydromagnetic deformation associated with the mountain. The magnetic field lines are curved more gently than in previous calculations, and the screening of the dipole moment is reduced. Quantitatively, it is found that the dimensionless dipole moment (md) depends on the accreted mass (Ma) as md = −3.2 × 103Ma/M⊙ + 1.0, implying approximately three times less screening compared to the Newtonian theory. Additionally, the characteristic scale height of the mountain, governing the gradients of quantities like pressure, density, and magnetic field strength, reduces by approximately 40  per cent for an isothermal equation of state.
  • Item
    No Preview Available
    A 3D printed flow sensor for microfluidic applications
    Hawke, A ; Concilia, G ; Thurgood, P ; Ahnood, A ; Baratchi, S ; Khoshmanesh, K (ELSEVIER SCIENCE SA, 2023-11-01)