Melbourne Dental School - Research Publications

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    The Impact of Molar Incisor Hypomineralisation on Children and Adolescents: A Narrative Review
    Shields, S ; Chen, T ; Crombie, F ; Manton, DJ ; Silva, M (MDPI, 2024-02)
    Molar incisor hypomineralisation (MIH) is a qualitative developmental enamel defect with a prevalence of 13% worldwide. This review aims to outline the current evidence regarding the impact of MIH on children's oral health and, more broadly, their day-to-day activities. MIH is associated with negative sequelae, including hypersensitivity, post-eruptive breakdown, the rapid development of carious lesions and poor aesthetics. Other concerns pertain to the clinical management of MIH and include difficulty in achieving local anaesthesia, increased dental fear and anxiety (DFA) and increased behaviour management problems. Oral health-related quality of life (OHRQoL) is the most standardised measure of patient impact; however, no instruments have been validated for use in MIH populations. The few existing observational studies investigating the impact of MIH on OHRQoL in children have produced conflicting results. Interventions to alleviate hypersensitivity and improve aesthetics had a positive impact on the OHRQoL of MIH-affected children. Multiple methodological issues make it difficult to measure the impact of MIH, including heterogeneity in the MIH severity classification, an overlap in the indices used to diagnose dental caries and MIH as well as the subjectivity of outcome measures for hypersensitivity and DFA.
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    Preparedness for practice of newly qualified dental practitioners in the Australian context: an exploratory study
    Marino, R ; Delany, C ; Manton, DJ ; Reid, K ; Satur, J ; Crombie, F ; Wong, R ; McNally, C ; Adams, GG ; Lopez, D ; Celentano, A ; Lim, M ; Morgan, M (BMC, 2022-08-18)
    BACKGROUND: The current study explored the perspectives of preparedness for dental practice from a range of relevant stakeholders (i.e., educators, employers, final-year students, graduates, practitioners, and professional associations) using an anonymous online survey in which participants described either their preparedness for practice, or the preparedness of graduates they have encountered, across six domains. RESULTS: A total of 120 participants completed the survey. Participants were from several Australian states and territories; regional, rural, and urban locations; and working in the public and private sector. Students and new graduates generally felt prepared for activities in all the identified domains. Stakeholders reported consistently that the knowledge of dental profession graduates was at the required level to enter practice in Australia in a safe way. Activities involving the knowledge of clinical entrepreneurship and financial solvency were the dimensions where students and graduates felt least prepared (e.g., explaining fees, negotiating finances). In the domains involving clinical and technical competencies, students and new graduates self-assessed as less prepared around managing dental trauma and medical emergencies. On the other hand, activities around social and community orientation, and to a lesser extent professional attitudes and ethical judgements, were the dimensions where students and graduates felt the most prepared. CONCLUSIONS: Present findings indicate that there appear to be good standards of preparedness for practice for graduate dental professionals. This exploratory study provides insights into the nature of preparedness for Australian dental professionals and provides a basis for targeting education and professional development to address areas of need.
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    Preparedness for practice of newly qualified dental professionals in Australia-educator, employer, and consumer perspectives
    Marino, R ; Delany, C ; Manton, D ; Reid, K ; Satur, J ; Crombie, F ; Wong, R ; McNally, C ; Lopez, D ; Celentano, A ; Lim, M ; Morgan, M (BMC, 2022-05-23)
    BACKGROUND: Limited data regarding the perspectives of other observers (i.e. those who educate, employ or receive care from) of new graduates' preparedness to practice is available. The present study aimed to explore perceptions of different observers regarding the preparedness to practice and work readiness of newly qualified dental professionals. This broader range of perspectives is crucial to inform the development of educational programs, including continuing professional development, for newly qualified dental professionals, by clarifying the skills, knowledge and behaviours expected by the dental profession and wider public. RESULTS: Nineteen individual qualitative interviews were undertaken. Interview participants included clinical demonstrators (n = 9; 2 Oral Health Therapists; 5 Dentists; and 2 Prosthetists), dental course convenors (n = 4), representatives of large employers (n = 2), and consumers (n = 4). According to this diverse group of respondents, dental students receive adequate theoretical and evidence-based information in their formal learning and teaching activities, which prepares them for practice as dental professionals. There were no specific clinical areas or procedures where preparedness was highlighted as a major concern. Notwithstanding this, specific graduate skills which would benefit from further training and consolidation were identified, including areas where higher levels of experience would be beneficial. Nonetheless, respondents indicated that new graduates were aware of their limitations and had developed self-discipline and ethics that would allow them to identify conditions/situations where they would not have the experience or expertise to provide care safely. CONCLUSIONS: From an observer perspective, dental students appeared to have gained adequate theoretical and evidence-based information in their formal learning and teaching activities to prepared them to commence practicing safely as dental professionals. Areas were identified in which new graduates were underprepared and when transitional support may be required.
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    The COVID-19 pandemic and its global effects on dental practice. An International survey
    Campus, G ; Betancourt, MD ; Cagetti, MG ; Giacaman, RA ; Manton, DJ ; Douglas, GVA ; Carvalho, TS ; Carvalho, JC ; Vukovic, A ; Cortes-Martinicorena, FJ ; Bourgeois, D ; Machiulskiene, V ; Sava-Rosianu, R ; Krithikadatta, J ; Morozova, NS ; Acevedo, AM ; Agudelo-Suarez, AA ; Aguirre, G ; Aguirre, K ; Alfonso, I ; Ghaffar, HA ; El Fadl, RA ; Al Maghlouth, SA ; Almerich-Torres, T ; Amadori, F ; Antia, K ; Bajric, E ; Barbosa-Liz, DM ; Ben-Tanfous, S ; Bieber, H ; Bhusari, S ; Birch, S ; Bonta, G ; Bottenberg, P ; Bruers, JJ ; Bustillos, L ; Buhrens, P ; Cai, J ; Cairoli, JL ; Carrer, FCA ; Correa, MB ; Cortes-Acha, B ; Carrouel, F ; de Carvalho Oliveira, R ; Cocco, F ; Crombie, F ; Csikar, J ; Declerck, D ; Denkovski, M ; Deschner, J ; Dopico-San Martin, J ; Dudnik, OV ; Escobar, WY ; Elwishahy, A ; Fernandez, CE ; Fontana, M ; Pericchi, AF ; Ghorbe, M ; Gigineishvili, E ; Quintan, AG ; Gray, J ; Gugnani, N ; Gambetta-Tessini, K ; Hai-dera, A ; Hopcraft, M ; Huttmanna, J ; Hysenaj, N ; Jalal, A ; Jikia, M ; John, J ; Kaps-Richter, G ; Tedesco, TK ; Leon, S ; Levin, KA ; Lew, HP ; Moreira Machado, MA ; MacLennan, AB ; Mafeni, JO ; Braga, MM ; Montiel-Company, JM ; Mal-erb, A ; Mamedo, AA ; Mani, SA ; Marouane, O ; Markovic, D ; Martinez, EP ; Maroufidis, N ; Mendes, FM ; Mendez, CF ; Musa, S ; Necibi, A ; Nor, NAM ; Ojukwu, BT ; Opdam, N ; Ottolenghi, L ; Owen, J ; Passaro, A ; Persoon, IF ; Peric, T ; Pesaressi-Torres, E ; Philippides, V ; Plaza-Ruiz, SP ; Raggio, DP ; Rivas Cartagen, FJ ; Ramos-Gomez, F ; Sabashvili, M ; Solis Sanchez, G ; Villena Sarmiento, R ; Schrader, H ; Serban, S ; Bairstow, R ; Senn, A ; Shi, B ; Sim, CPC ; Slabsinskiene, E ; Spagnuolo, G ; Squassi, AF ; Taiwo, OO ; Thodhorjani, A ; Tietler, P ; Volgenant, CMC ; van der Veen, MH ; Vlahovic, Z ; Visaria, A ; Romero Uzcategui, Y ; Xhajanka, E ; Yan, Q ; Zeng, O ; Zeyer, O ; Zukanovic, A ; Wolf, TG (ELSEVIER SCI LTD, 2021-11)
    OBJECTIVES: A multicentre survey was designed to evaluate the impact of COVID-19 outbreak on dental practice worldwide, estimate the COVID-19 related symptoms/signs, work attitudes and behaviour and the routine use of protective measures and Personal Protective Equipment (PPE). METHODS: A global survey using a standardized questionnaire with research groups from 36 countries was designed. The questionnaire was developed and pretested during April 2020 and contained three domains: 1) Personal data; 2) COVID-19 positive rate and symptoms/signs presumably related to the coronavirus; 3) Working conditions and PPE adopted after the outbreak. Countries' data were grouped by the Country Positive Rate (CPR) during the survey period and by Gross-National-Income per capita. An ordinal multinomial logistic regression model was carried out with COVID-19 self-reported rate referred by dental professionals as dependent variable to assess the association with questionnaire items. RESULTS: A total of 52,491 questionnaires were returned with a male/female ratio of 0.63. Out of the total respondents, 7,859 dental professionals (15%) reported symptoms/signs compatible with COVID-19. More than half of the sample (n = 27,818; 53%) stated to use FFP2/N95 masks, while 21,558 (41.07%) used eye protection. In the bivariate analysis, CPR and N95/FFP2 were significantly associated (OR = 1.80 95%CI = 1.60/2.82 and OR = 5.20 95%CI = 1.44/18.80, respectively), while Gross-National-Income was not statistically associated with CPR (OR = 1.09 95%CI = 0.97/1.60). The same significant associations were observed in the multivariate analysis. CONCLUSIONS: Oral health service provision has not been significantly affected by COVID-19, although access to routine dental care was reduced due to country-specific temporary lockdown periods. While the dental profession has been identified at high-risk, the reported rates of COVID-19 for dental professionals were not significantly different to those reported for the general population in each country. These findings may help to better plan oral health care for future pandemic events.
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    Evaluation of a community-based early childhood caries (ECC) intervention in Cambodia
    Turton, B ; Durward, C ; Crombie, F ; Sokal-Gutierrez, K ; Soeurn, S ; Manton, DJ (WILEY, 2021-06)
    OBJECTIVE: To critically evaluate an early childhood caries (ECC) intervention performed by non-dental primary healthcare providers. METHODS: This mixed-methods investigation includes data from three sources: (a) a pilot non-randomized controlled trial to examine clinical outcomes at four health centres; (b) stakeholder focus group interviews; and (c) a survey of parents whose children were exposed to the intervention. The pilot study involved four Community Health Centres in rural Cambodia whereby mother-child (6-24 months of age)dyads received oral health education (OHE), toothbrushes, fluoride toothpaste and fluoride varnish on up to six occasions as part of the routine vaccination schedule. Outcomes were as follows: presence of ECC; impacts on oral health-related quality of life (OHRQoL); stakeholder perceptions of intervention delivery; and parental perceptions of fluoride varnish. RESULTS: Participants in the intervention group had six times lower odds of developing ECC than those in the comparison group after controlling for socio-economic status (OR 0.13). Those in the intervention group also had a large reduction OHRQoL scale scores. Key knowledge and practice gaps were identified among stakeholders. Surveyed parents had favourable views of the fluoride varnish placement by medical professionals, and four out of five stated that they would recommend fluoride varnish for other children. Primary healthcare providers, commune council representatives and community health promoters supported oral health interventions being provided in CHCs. CONCLUSIONS: OHE and fluoride varnish interventions provided by non-dental primary health workers were feasible and acceptable for stakeholders in a Cambodian setting. The intervention group had lower ECC experience and better OHRQoL at 2 years of age.
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    Response to letter to the editor by Jan Kuhnisch
    Schwendicke, F ; Splieth, C ; Breschi, L ; Banerjee, A ; Fontana, M ; Paris, S ; Burrow, M ; Crombie, F ; Page, LF ; Gaton-Hernandez, P ; Giacaman, RA ; Gugnani, N ; Hickel, R ; Jordan, RA ; Leal, S ; Lo, E ; Tassery, H ; Thomson, WM ; Manton, DJ (SPRINGER HEIDELBERG, 2020-06)
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    Characterisation of developmentally hypomineralised human enamel
    Crombie, FA ; Manton, DJ ; Palamara, JEA ; Zalizniak, I ; Cochrane, NJ ; Reynolds, EC (ELSEVIER SCI LTD, 2013-07)
    OBJECTIVES: To investigate and clarify physical and chemical properties of enamel affected by molar incisor hypomineralisation (MIH). METHODS: A series of in vitro studies were performed on extracted molars affected by MIH and sound teeth for controls. Tooth sections underwent Vickers microhardness testing before lapping and subsequent transverse microradiographic analysis and examination under polarised light microscopy. Carbonate content was determined by CO2 release from acid digestion. Unprepared and fractured surfaces were examined under scanning electron microscopy. RESULTS: MIH-affected molars demonstrated a severe degree of hypomineralisation with an average mineral content of only 58.8%vol% mineral. Vickers microhardness was significantly reduced in MIH compared with controls (1.8±1.1 v 4.4±1.0 GPa, p<0.05) and polarised light microscopy revealed the bulk of MIH lesions had a porosity of ≤5% but also substantial areas of ≥10% and smaller areas exceeding 25% porosity. A surface layer was frequently observed on both intact and broken-down lesions and cervical regions of MIH teeth were typically spared. Carbonate content of MIH enamel was higher than control samples (6.6±2.1 v 4.4±1.1 wt%, p<0.05). Scanning electron microscopy showed that both the enamel rod and surface ultrastructure were defective. Clinical characteristics did not consistently correlate with all properties. CONCLUSIONS: The properties of MIH-affected enamel significantly differ from those of normal enamel and were highly variable, however some common characteristics were observed. Implications for aetiology and clinical management are discussed.