Paediatrics (RCH) - Research Publications

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Author: Bines, Julie × End date: 2009 × Start date: 2004 × Type: Journal Article ×

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    The burden of hospitalised rotavirus infections in Fiji
    Jenney, A ; Tikoduadua, L ; Buadromo, E ; Barnes, G ; Kirkwood, CD ; Boniface, K ; Bines, J ; Mulholland, K ; Russell, F (ELSEVIER SCI LTD, 2009-11-20)
    Rotavirus is the most common cause of acute severe dehydrating diarrhoea in young children worldwide. We describe the burden of rotavirus disease and the rotavirus types causing it in the largest city in Fiji. During 2006 and 2007, 592 children under 5 years of age were admitted to hospital in Suva, Fiji with acute diarrhoea. Of the 454 children for whom a stool specimen was tested, 39% were positive for rotavirus and the predominant strain found was the serotype G3[P8]. There is a significant burden of disease due to rotavirus in Fiji and the introduction of rotavirus vaccines into the national immunization schedule may drastically reduce inpatient diarrhoeal disease.
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    Validation of clinical case definition of acute intussusception in infants in Viet Nam and Australia
    BINES, JULIE ; Liem, Nguyen Thanh ; Justice, Frances ; Son, Tran Ngoc ; CARLIN, JOHN ; DE CAMPO, MARGARET ; JAMSEN, KRIS ; Mulholland, Edward ; BARNETT, PETER ; BARNES, GRAEME ( 2006)
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    Risk factors for intussception in infants in Vietnam and Australia: Adenovirus implicated, but not rotavirus
    BINES, JULIE ; Liem, Nguyen Thanh ; Justice, Frances ; Son, Tran Ngoc ; KIRKWOOD, CARL ; DE CAMPO, MARGARET ; BARNETT, PETER ; BISHOP, RUTH ; ROBINS-BROWNE, ROY ; CARLIN, JOHN ( 2006)
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    Molecular epidemiology of adenovirus isolates from patients diagnosed with intussusception in Melbourne, Australia
    Selvaraj, G ; Kirkwood, C ; Bines, J ; Buttery, J (AMER SOC MICROBIOLOGY, 2006-09)
    Twenty-one intussusception (IS)-associated and 59 temporally linked adenoviral isolates from clinical infections were compared. Species C (15/21 IS- and 32/59 non-IS-associated isolates) dominated. Of these, serotype 2 (AdV-2) (7/15 IS-associated isolates) and serotype 1 (AdV-1) (16/32 non-IS-associated isolates) were the most commonly identified serotypes. DNA restriction analysis of AdV-2 isolates identified six genomic types; of these, type D2 (3/7 IS- and 8/11 non-IS-associated isolates) was the dominant type after BamHI and SmaI digestion. IS-associated isolates are similar to circulating non-IS-associated strains.