Paediatrics (RCH) - Research Publications

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End date: 2009 × Author: Buttery, Jim × Author: Bines, Julie ×

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    Molecular epidemiology of adenovirus isolates from patients diagnosed with intussusception in Melbourne, Australia
    Selvaraj, G ; Kirkwood, C ; Bines, J ; Buttery, J (AMER SOC MICROBIOLOGY, 2006-09)
    Twenty-one intussusception (IS)-associated and 59 temporally linked adenoviral isolates from clinical infections were compared. Species C (15/21 IS- and 32/59 non-IS-associated isolates) dominated. Of these, serotype 2 (AdV-2) (7/15 IS-associated isolates) and serotype 1 (AdV-1) (16/32 non-IS-associated isolates) were the most commonly identified serotypes. DNA restriction analysis of AdV-2 isolates identified six genomic types; of these, type D2 (3/7 IS- and 8/11 non-IS-associated isolates) was the dominant type after BamHI and SmaI digestion. IS-associated isolates are similar to circulating non-IS-associated strains.