Paediatrics (RCH) - Research Publications

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    Injury
    Greenham, M ; Ryan, N ; Anderson, V ; Gibb, R ; Kolb, B (Elsevier, 2017-11-02)
    Exploration of the consequences of brain insult sustained early in life has a long history, dating back to the 1920s and the seminal works of Lashley (1929), Kennard (1938, 1942), and Hebb (1949), and later comprehensive reviews (e.g., Finger & Stein, 1982; Isaacson, 1975; St James-Roberts, 1975). In this literature, while insults in infancy and early childhood were regarded as qualitatively and quantitatively distinct from those occurring in adulthood, there was little agreement regarding the potential benefits and vulnerabilities of early brain insult.
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    Pneumonia
    Howie, SRC ; Hamer, DH ; GRAHAM, S ; Quah, SR (Elsevier, 2017)
    Pneumonia is an important cause of morbidity and mortality globally. It is the leading cause of death in infants and young children with the majority of these deaths occurring in low income countries. Risk factors affecting incidence and outcome include extremes of age, poor nutrition, immunosuppression, environmental exposures and socioeconomic determinants. Pneumonia can be caused by a wide range of pathogens including bacteria, viruses and fungi, and the etiology varies by epidemiological setting, comorbidities and whether the pneumonia is community-acquired or hospital-acquired. Streptococcus pneumoniae is the major cause of community-acquired bacterial pneumonia while Gram negative bacteria, often resistant to multiple antibiotics, are common causes of hospital-acquired pneumonia and pneumonia in immunosuppressed individuals. Diagnosis is generally clinical and management is based mainly on knowledge of likely causative pathogens as well as clinical severity and presence of known risk factors. Timely and effective antibiotic treatment and oxygen therapy if hypoxemic are critical to patient outcomes. Preventive measures range from improved nutrition and hygiene to specific vaccines that target common causes in children and adults such as the pneumococcal or influenza vaccines.
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    The Roadmap for Childhood Tuberculosis.
    GRAHAM, S ; Detjen, AK ; Starke, JR ; Donald, PR (Oxford University Press, 2016-02-11)
    The Handbook of Child and Adolescent Tuberculosis is a state of the art clinical reference written and edited by the world's leading experts in childhood tuberculosis.
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    Pneumonia in HIV-infected children.
    GRAHAM, S ; Mulholland, K ; Weber, MW (Pinter & Martin Ltd, 2016-02-29)
    A key text about the global health issue of pneumonia, written by experts in the field.
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    Child Development and Disability
    Efron, D ; Marraffa, C ; Reilly, S ; REDDIHOUGH, D (Wiley Blackwell, 2015)
    Resident Medical Officers' Handbook, Lawson JS, ed. (Foreword: Sloan LEG). 100 p. Snap-lock ring binder. 2nd edition (1975–1976).Residents Handbook, Roy N, Vance J, eds. (Foreword: Sloan LEG). 203 p. Snap-lock ring binder.
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    Antiallergic Strategies: Induction of Tolerance to Food
    Lack, G ; Santos, A ; Penagos, M ; Allen, K ; Wahn, ; Sampson, (Academic Press, 2015-01-01)
    In addition, the book unites key, global experts in the field who summarize their collective, and current, knowledge of the early stage of the "Atopic March", along with novel ideas for potential options of prevention.
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    Prevention and Natural History of Food Allergy
    Prescott, S ; ALLEN, K ; Leung, DYM ; Szefler, SJ ; Bonilla, FA ; Akdis, CA ; Sampson, H (Elsevier Health Sciences, 2016)
    The third edition of Pediatric Allergy continues this title's steadfast tradition of providing comprehensive, authoritative guidance on the day-to-day diagnosis and management of pediatric allergic and immunologic diseases.
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    Eosinophilic Oesophagitis
    ALLEN, K ; Heine, R ; Ebisawa, M ; Ballmer-Weber, BK ; Vieths, S ; Wood, RA (Karger, 2015)
    Featuring contributions by world-renowned experts, this book presents the current concept, practice and recent advances in the field of food allergy.