School of Mathematics and Statistics - Research Publications
http://hdl.handle.net/11343/294
2020-07-08T08:58:39Z
2020-07-08T08:58:39Z
Assessment of serum symmetric dimethylarginine and creatinine concentrations in hyperthyroid cats before and after a fixed dose of orally administered radioiodine
Yu, L
Lacorcia, L
Finch, S
Johnstone, T
http://hdl.handle.net/11343/240445
2020-07-07T19:19:59Z
2020-01-01T00:00:00Z
Yu, L; Lacorcia, L; Finch, S; Johnstone, T
2020
Assessment of serum symmetric dimethylarginine and creatinine concentrations in hyperthyroid cats before and after a fixed dose of orally administered radioiodine
Background: Serum symmetric dimethylarginine (SDMA) is a sensitive renal biomarker for detecting early chronic kidney disease (CKD) in nonhyperthyroid cats, but knowledge regarding its performance in hyperthyroid cats remains limited.
Objectives: To determine the relationship between serum SDMA, creatinine and total thyroxine (TT4) concentrations in hyperthyroid cats before (T0) and 3 months after (T1) receiving a PO fixed dose of radioiodine.
Animals: Eighty client‐owned hyperthyroid cats.
Methods: Prospective cohort study. Serum TT4, and SDMA, creatinine concentrations, and urine specific gravity were measured at T0 and T1. Nonparametric tests were used to determine the relationship among SDMA, and creatinine and TT4 concentrations. Agreement between SDMA and creatinine regarding CKD staging at both time points was assessed using Goodman and Kruskal's gamma statistic.
Results: Mean serum SDMA concentration increased after treatment of hyperthyroidism. However, 21 of 75 cats experienced a decrease in SDMA between T0 and T1, whereas creatinine decreased in only 2 cats. A moderate correlation between SDMA and creatinine was seen at T1 (r = 0.53; P < .001) but not at T0 (r = 0.13; P = .25). Where assessable at T1, poor agreement was observed between SDMA and creatinine and CKD stage (Goodman and Kruskal's gamma 0.20; P = .29).
Conclusions and clinical importance: Discordant outcomes between SDMA and creatinine after radioiodine treatment in cats with hyperthyroidism suggest extrarenal factors may interfere with the reliability of SDMA to adequately reflect renal function. As a result, SDMA should not be interpreted in isolation in hyperthyroid cats treated with radioiodine.
Journal Article
2020-01-01T00:00:00Z
A few clarifications on MIRIBEL
Faria, M
Bjornmalm, M
Crampin, EJ
Caruso, F
http://hdl.handle.net/11343/235829
2020-07-07T14:01:13Z
2020-01-01T00:00:00Z
Faria, M; Bjornmalm, M; Crampin, EJ; Caruso, F
2020-01-01
A few clarifications on MIRIBEL
We are inspired by the responses1,2,3,4 to our recently proposed ‘reporting standards’ for bio–nano research (Minimum Information Reporting in Bio–Nano Experimental Literature — MIRIBEL)5. However, we wish to clarify several points made in MIRIBEL and discuss a few concerns raised by the community, with a view toward encouraging uptake of the MIRIBEL standard and improving future research.
Journal Article
2020-01-01T00:00:00Z
The mean-square dichotomy spectrum and a bifurcation to a mean-square attractor
Doan, TS
Rasmussen, M
Kloeden, PE
http://hdl.handle.net/11343/51722
2020-07-05T08:24:52Z
2015-05-01T00:00:00Z
Doan, TS; Rasmussen, M; Kloeden, PE
2015-05-01
The mean-square dichotomy spectrum and a bifurcation to a mean-square attractor
The dichotomy spectrum is introduced for linear mean-square random dynamical systems, and it is shown that for finite-dimensional mean-field stochastic differential equations, the dichotomy spectrum consists of finitely many compact intervals. It is then demonstrated that a change in the sign of the dichotomy spectrum is associated with a bifurcation from a trivial to a non-trivial mean-square random attractor.
Journal Article
2015-05-01T00:00:00Z
Learning arithmetic blocks: a concrete model for teaching decimals
Archer, Shona
Condon, Caroline
STACEY, KAYE
STEINLE, VICKI
McCarthy, Heather
Helme, Sue
Sullivan, Gerard
Tromp, Calvin
http://hdl.handle.net/11343/35042
2020-04-04T18:11:55Z
2006-01-01T00:00:00Z
Archer, Shona; Condon, Caroline; STACEY, KAYE; STEINLE, VICKI; McCarthy, Heather; Helme, Sue; Sullivan, Gerard; Tromp, Calvin
2006
Learning arithmetic blocks: a concrete model for teaching decimals
This booklet is an introduction to using the LAB model with your students. It outlines a number of activities using LAB to assist students in gaining an understanding of the decimal number system.
Copyright confirmation in progress. Any queries to UMER-enquiries@unimelb.edu.au
Book
2006-01-01T00:00:00Z
Lesson ideas and activities for teaching decimals
Condon, Caroline
Archer, Shona
STACEY, KAYE
STEINLE, VICKI
Scott, Nick
Helme, Sue
Sullivan, Gerard
Tromp, Calvin
http://hdl.handle.net/11343/35041
2020-04-04T18:11:46Z
2006-01-01T00:00:00Z
Condon, Caroline; Archer, Shona; STACEY, KAYE; STEINLE, VICKI; Scott, Nick; Helme, Sue; Sullivan, Gerard; Tromp, Calvin
2006
Lesson ideas and activities for teaching decimals
The Department of Science and Mathematics Education has produced this booklet to assist teachers with students learning to work confidently with decimal numbers. It contains many classroom activities that will motivate and engage students making the teaching and learning of decimals both enjoyable and effective.
Copyright confirmation in progress. Any queries to UMER-enquires@unimelb.edu.au; Further information regarding the book is available at http://staff.edfac.unimelb.edu.au/~kayecs/projects/decprojlink.htm
Book
2006-01-01T00:00:00Z
Frobenius circulant graphs of valency four
Thomson, Alison
ZHOU, SANMING
http://hdl.handle.net/11343/33003
2020-04-04T11:04:32Z
2008-01-01T00:00:00Z
Thomson, Alison; ZHOU, SANMING
2008
Frobenius circulant graphs of valency four
A first kind Frobenius graph is a Cayley graph Cay.K; S/ on the Frobenius kernel of a Frobenius group K o H such that S D aH for some a 2 K with haH i D K, where H is of even order or a is an involution. It is known that such graphs admit ‘perfect’ routing and gossiping schemes. A circulant graph is a Cayley graph on a cyclic group of order at least three. Since circulant graphs are widely used as models for interconnection networks, it is thus highly desirable to characterize those which are Frobenius of the first kind. In this paper we first give such a characterization for connected 4-valent circulant graphs, and then describe optimal routing and gossiping schemes for those which are first kind Frobenius graphs. Examples of such graphs include the 4-valent circulant graph with a given diameter and maximum possible order.
© 2008 Australian Mathematical Society. Online edition of the journal is available at http://journals.cambridge.org/JAZ
Journal Article
2008-01-01T00:00:00Z
Queueing analysis of network traffic: methodology and visualization tools
ROLLS, D.
MICHAILIDIS, G.
HERNANDEZ-CAMPOS, F.
http://hdl.handle.net/11343/30695
2020-04-04T03:39:17Z
2005-01-01T00:00:00Z
ROLLS, D.; MICHAILIDIS, G.; HERNANDEZ-CAMPOS, F.
2005
Queueing analysis of network traffic: methodology and visualization tools
Journal Article
2005-01-01T00:00:00Z
The density of the time to ruin for a Sparre Andersen process with Erlang arrivals and exponential claims
DICKSON, D.
HUGHES, B.
ZHANG, L.
http://hdl.handle.net/11343/29538
2020-04-03T23:36:01Z
2005-01-01T00:00:00Z
DICKSON, D.; HUGHES, B.; ZHANG, L.
2005
The density of the time to ruin for a Sparre Andersen process with Erlang arrivals and exponential claims
Journal Article
2005-01-01T00:00:00Z
Positive and real-positive solutions to the equation axa* = c in C*-algebras
CVETKOVI-ILIC, D.
DAJIC, A.
KOLIHA, J.
http://hdl.handle.net/11343/29238
2020-04-03T22:39:41Z
2007-01-01T00:00:00Z
CVETKOVI-ILIC, D.; DAJIC, A.; KOLIHA, J.
2007
Positive and real-positive solutions to the equation axa* = c in C*-algebras
Journal Article
2007-01-01T00:00:00Z
Finite symmetric graphs with 2-arc transitive quotients II
LU, Z.
ZHOU, S.
http://hdl.handle.net/11343/29231
2020-04-03T22:38:21Z
2007-01-01T00:00:00Z
LU, Z.; ZHOU, S.
2007
Finite symmetric graphs with 2-arc transitive quotients II
Journal Article
2007-01-01T00:00:00Z
Specht modules and semisimplicity criteria for Brauer and Birman-Murakami-Wenzl algebras
ENYANG, J.
http://hdl.handle.net/11343/29226
2020-04-03T22:37:17Z
2007-01-01T00:00:00Z
ENYANG, J.
2007
Specht modules and semisimplicity criteria for Brauer and Birman-Murakami-Wenzl algebras
Journal Article
2007-01-01T00:00:00Z
Some infinite soluble groups, their modules, and the arithmeticity of associated automorphism groups
BROOKES, C.
GROVES, J.
http://hdl.handle.net/11343/29223
2020-04-03T22:36:47Z
2005-01-01T00:00:00Z
BROOKES, C.; GROVES, J.
2005
Some infinite soluble groups, their modules, and the arithmeticity of associated automorphism groups
Journal Article
2005-01-01T00:00:00Z
An application of classical invariant theory to identifiability in nonparametric mixtures
ELMORE, R.
HALL, P.
NEEMAN, A.
http://hdl.handle.net/11343/29222
2020-04-03T22:36:39Z
2005-01-01T00:00:00Z
ELMORE, R.; HALL, P.; NEEMAN, A.
2005
An application of classical invariant theory to identifiability in nonparametric mixtures
Journal Article
2005-01-01T00:00:00Z
Spectral curves and the mass of hyperbolic monopoles
NORBURY, P.
ROMAO, N.
http://hdl.handle.net/11343/29213
2020-04-03T22:35:05Z
2007-01-01T00:00:00Z
NORBURY, P.; ROMAO, N.
2007
Spectral curves and the mass of hyperbolic monopoles
Journal Article
2007-01-01T00:00:00Z
Angle structures and normal surfaces
LUO, F.
TILLMANN, S.
http://hdl.handle.net/11343/27840
2020-04-03T18:20:55Z
2008-01-01T00:00:00Z
LUO, F.; TILLMANN, S.
2008
Angle structures and normal surfaces
C1 - Refereed Journal Article
Journal Article
2008-01-01T00:00:00Z
Alcove walks, Hecke algebras, spherical functions, crystals and column strict tableaux
RAM, A.
http://hdl.handle.net/11343/27835
2020-04-03T18:19:55Z
2006-01-01T00:00:00Z
RAM, A.
2006
Alcove walks, Hecke algebras, spherical functions, crystals and column strict tableaux
C1 - Refereed Journal Article
Journal Article
2006-01-01T00:00:00Z
String topology prospectra and Hochschild cohomology
GRUHER, K.
WESTERLAND, C.
http://hdl.handle.net/11343/27831
2020-04-03T18:19:03Z
2008-01-01T00:00:00Z
GRUHER, K.; WESTERLAND, C.
2008
String topology prospectra and Hochschild cohomology
C1 - Refereed Journal Article
Journal Article
2008-01-01T00:00:00Z
Finite symmetric graphs with two-arc transitive quotients
IRANMANESH, M. A.
PRAEGER, C. E.
ZHOU, S.
http://hdl.handle.net/11343/27825
2020-04-03T18:17:52Z
2005-01-01T00:00:00Z
IRANMANESH, M. A.; PRAEGER, C. E.; ZHOU, S.
2005
Finite symmetric graphs with two-arc transitive quotients
C1 - Refereed Journal Article
Journal Article
2005-01-01T00:00:00Z
An oscillation theorem for groups of isometries
HJORTH, G.
http://hdl.handle.net/11343/27818
2020-04-03T18:16:19Z
2008-01-01T00:00:00Z
HJORTH, G.
2008
An oscillation theorem for groups of isometries
C1 - Refereed Journal Article
Journal Article
2008-01-01T00:00:00Z
Minimal spheres of arbitrarily high morse index
HASS, J.
NORBURY, P. T.
RUBINSTEIN, J. H.
http://hdl.handle.net/11343/27815
2020-04-03T18:15:41Z
2003-01-01T00:00:00Z
HASS, J.; NORBURY, P. T.; RUBINSTEIN, J. H.
2003
Minimal spheres of arbitrarily high morse index
C1 - Refereed Journal Article
Journal Article
2003-01-01T00:00:00Z
Integrable lattice realisations of conformal twisted boundary conditions
CHUI, CHEUK HO OTTO
MERCAT, CHRISTIAN
ORRICK, WILLIAM PENDLETON
PEARCE, PAUL ANTHONY
http://hdl.handle.net/11343/26184
2020-04-03T11:48:10Z
2001-01-01T00:00:00Z
CHUI, CHEUK HO OTTO; MERCAT, CHRISTIAN; ORRICK, WILLIAM PENDLETON; PEARCE, PAUL ANTHONY
2001
Integrable lattice realisations of conformal twisted boundary conditions
C1 - Journal Articles Refereed
Journal Article
2001-01-01T00:00:00Z
Self-Avoiding Random Walk with Multiple Site Weightings and Restrictions
KRAWCZYK, JAROSLAW
PRELLBERG, THOMAS
OWCZAREK, ALEKSANDER
RECHNITZER, ANDREW
http://hdl.handle.net/11343/26175
2020-04-03T11:46:40Z
2006-01-01T00:00:00Z
KRAWCZYK, JAROSLAW; PRELLBERG, THOMAS; OWCZAREK, ALEKSANDER; RECHNITZER, ANDREW
2006
Self-Avoiding Random Walk with Multiple Site Weightings and Restrictions
C1 - Journal Articles Refereed
Journal Article
2006-01-01T00:00:00Z
A parallel algorithm for the enumeration of self-avoiding polygons on the square lattice
JENSEN, IWAN
http://hdl.handle.net/11343/26160
2020-04-03T11:43:44Z
2003-01-01T00:00:00Z
JENSEN, IWAN
2003
A parallel algorithm for the enumeration of self-avoiding polygons on the square lattice
C1 - Journal Articles Refereed
Journal Article
2003-01-01T00:00:00Z
Interpretations of some parameter dependent generalizations of classical matrix ensembles
FORRESTER, PETER JOHN
RAINS, ERIC
http://hdl.handle.net/11343/26129
2020-04-03T11:37:47Z
2005-01-01T00:00:00Z
FORRESTER, PETER JOHN; RAINS, ERIC
2005
Interpretations of some parameter dependent generalizations of classical matrix ensembles
C1 - Journal Articles Refereed
Journal Article
2005-01-01T00:00:00Z
Semantics-Based Composition of Integrated Cardiomyocyte Models Motivated by Real-World Use Cases
Neal, ML
Carlson, BE
Thompson, CT
James, RC
Kim, KG
Tran, K
Crampin, EJ
Cook, DL
Gennari, JH
http://hdl.handle.net/11343/58794
2020-07-05T08:24:52Z
2015-12-30T00:00:00Z
Neal, ML; Carlson, BE; Thompson, CT; James, RC; Kim, KG; Tran, K; Crampin, EJ; Cook, DL; Gennari, JH
2015-12-30
Semantics-Based Composition of Integrated Cardiomyocyte Models Motivated by Real-World Use Cases
Semantics-based model composition is an approach for generating complex biosimulation models from existing components that relies on capturing the biological meaning of model elements in a machine-readable fashion. This approach allows the user to work at the biological rather than computational level of abstraction and helps minimize the amount of manual effort required for model composition. To support this compositional approach, we have developed the SemGen software, and here report on SemGen's semantics-based merging capabilities using real-world modeling use cases. We successfully reproduced a large, manually-encoded, multi-model merge: the "Pandit-Hinch-Niederer" (PHN) cardiomyocyte excitation-contraction model, previously developed using CellML. We describe our approach for annotating the three component models used in the PHN composition and for merging them at the biological level of abstraction within SemGen. We demonstrate that we were able to reproduce the original PHN model results in a semi-automated, semantics-based fashion and also rapidly generate a second, novel cardiomyocyte model composed using an alternative, independently-developed tension generation component. We discuss the time-saving features of our compositional approach in the context of these merging exercises, the limitations we encountered, and potential solutions for enhancing the approach.
Journal Article
2015-12-30T00:00:00Z
Representation theory of sl(2 vertical bar 1)
Gotz, G
Quella, T
Schomerus, V
http://hdl.handle.net/11343/91613
2020-07-05T08:24:52Z
2007-06-15T00:00:00Z
Gotz, G; Quella, T; Schomerus, V
2007-06-15
Representation theory of sl(2 vertical bar 1)
Journal Article
2007-06-15T00:00:00Z
Using Genetic Distance to Infer the Accuracy of Genomic Prediction
Scutari, M
Mackay, I
Balding, D
http://hdl.handle.net/11343/118556
2020-07-05T08:24:52Z
2016-09-01T00:00:00Z
Scutari, M; Mackay, I; Balding, D
2016-09-01
Using Genetic Distance to Infer the Accuracy of Genomic Prediction
The prediction of phenotypic traits using high-density genomic data has many applications such as the selection of plants and animals of commercial interest; and it is expected to play an increasing role in medical diagnostics. Statistical models used for this task are usually tested using cross-validation, which implicitly assumes that new individuals (whose phenotypes we would like to predict) originate from the same population the genomic prediction model is trained on. In this paper we propose an approach based on clustering and resampling to investigate the effect of increasing genetic distance between training and target populations when predicting quantitative traits. This is important for plant and animal genetics, where genomic selection programs rely on the precision of predictions in future rounds of breeding. Therefore, estimating how quickly predictive accuracy decays is important in deciding which training population to use and how often the model has to be recalibrated. We find that the correlation between true and predicted values decays approximately linearly with respect to either FST or mean kinship between the training and the target populations. We illustrate this relationship using simulations and a collection of data sets from mice, wheat and human genetics.
Journal Article
2016-09-01T00:00:00Z
Why weight? Modelling sample and observational level variability improves power in RNA-seq analyses
Liu, R
Holik, AZ
Su, S
Jansz, N
Chen, K
Leong, HS
Blewitt, ME
Asselin-Labat, M-L
Smyth, GK
Ritchie, ME
http://hdl.handle.net/11343/116098
2020-07-05T08:24:52Z
2015-09-03T00:00:00Z
Liu, R; Holik, AZ; Su, S; Jansz, N; Chen, K; Leong, HS; Blewitt, ME; Asselin-Labat, M-L; Smyth, GK; Ritchie, ME
2015-09-03
Why weight? Modelling sample and observational level variability improves power in RNA-seq analyses
Variations in sample quality are frequently encountered in small RNA-sequencing experiments, and pose a major challenge in a differential expression analysis. Removal of high variation samples reduces noise, but at a cost of reducing power, thus limiting our ability to detect biologically meaningful changes. Similarly, retaining these samples in the analysis may not reveal any statistically significant changes due to the higher noise level. A compromise is to use all available data, but to down-weight the observations from more variable samples. We describe a statistical approach that facilitates this by modelling heterogeneity at both the sample and observational levels as part of the differential expression analysis. At the sample level this is achieved by fitting a log-linear variance model that includes common sample-specific or group-specific parameters that are shared between genes. The estimated sample variance factors are then converted to weights and combined with observational level weights obtained from the mean-variance relationship of the log-counts-per-million using 'voom'. A comprehensive analysis involving both simulations and experimental RNA-sequencing data demonstrates that this strategy leads to a universally more powerful analysis and fewer false discoveries when compared to conventional approaches. This methodology has wide application and is implemented in the open-source 'limma' package.
Journal Article
2015-09-03T00:00:00Z
Boundary regularized integral equation formulation of the Helmholtz equation in acoustics
Sun, Q
Klaseboer, E
Khoo, B-C
Chan, DYC
http://hdl.handle.net/11343/116541
2020-07-05T08:24:52Z
2015-01-01T00:00:00Z
Sun, Q; Klaseboer, E; Khoo, B-C; Chan, DYC
2015-01-01
Boundary regularized integral equation formulation of the Helmholtz equation in acoustics
A boundary integral formulation for the solution of the Helmholtz equation is developed in which all traditional singular behaviour in the boundary integrals is removed analytically. The numerical precision of this approach is illustrated with calculation of the pressure field owing to radiating bodies in acoustic wave problems. This method facilitates the use of higher order surface elements to represent boundaries, resulting in a significant reduction in the problem size with improved precision. Problems with extreme geometric aspect ratios can also be handled without diminished precision. When combined with the CHIEF method, uniqueness of the solution of the exterior acoustic problem is assured without the need to solve hypersingular integrals.
Journal Article
2015-01-01T00:00:00Z
Asymmetrically gauged WZNW models
Quella, T
Schomerus, V
http://hdl.handle.net/11343/91633
2020-07-05T08:24:52Z
2003-01-01T00:00:00Z
Quella, T; Schomerus, V
2003-01-01
Asymmetrically gauged WZNW models
Journal Article
2003-01-01T00:00:00Z