• A new way of measuring apoptosis by absolute quantitation of inter-nucleosomally fragmented genomic DNA 

  Hooker, DJ; Mobarok, M; Anderson, JL; Rajasuriar, R; Gray, LR; Ellett, AM; Lewin, SR; Gorry, PR; Cherry, CL (OXFORD UNIV PRESS, 2012-08-01)

  Several critical events of apoptosis occur in the cell nucleus, including inter-nucleosomal DNA fragmentation (apoptotic DNA) and eventual chromatin condensation. The generation of apoptotic DNA has become a biochemical ...

• Comparison of HDAC inhibitors in clinical development Effect on HIV production in latently infected cells and T-cell activation 

  Rasmussen, TA; Sogaard, OS; Brinkmann, C; Wightman, F; Lewin, SR; Melchjorsen, J; Dinarello, C; Ostergaard, L; Tolstrup, M (TAYLOR & FRANCIS INC, 2013-05-01)

  OBJECTIVE: We aimed to compare the potential for inducing HIV production and the effect on T-cell activation of potent HDAC inhibitors undergoing clinical investigation. DESIGN: In vitro study RESULTS: The various HDAC ...

• The interaction of macrophage and non-macrophage tropic isolates of HIV-1 with thymic and tonsillar dendritic cells in vitro 

  Cameron, PU; Lowe, MG; Sotzik, F; Coughlan, AF; Crowe, SM; Shortman, K (ROCKEFELLER UNIV PRESS, 1996-04-01)

  Dendritic cells isolated from thymus and tonsil were tested for susceptibility to HIV-1 strains that are tropic for macrophages or for T cell lines. DCs were purified by cell sorting and before infection expressed high ...

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