Patterned Poly(dopamine) Films for Enhanced Cell Adhesion
AuthorChen, X; Cortez-Jugo, C; Choi, GH; Bjornmalm, M; Dai, Y; Yoo, PJ; Caruso, F
Source TitleBIOCONJUGATE CHEMISTRY
PublisherAMER CHEMICAL SOC
University of Melbourne Author/sCaruso, Francesco; Chen, Xi; Cortez-Jugo, Christina; Bjornmalm, Axel Mattias Hekansson; DAI, YUNLU
AffiliationChemical and Biomolecular Engineering
Document TypeJournal Article
CitationsChen, X; Cortez-Jugo, C; Choi, GH; Bjornmalm, M; Dai, Y; Yoo, PJ; Caruso, F, Patterned Poly(dopamine) Films for Enhanced Cell Adhesion, BIOCONJUGATE CHEMISTRY, 2017, 28 (1), pp. 75 - 80
Access StatusOpen Access
Engineered materials that promote cell adhesion and cell growth are important in tissue engineering and regenerative medicine. In this work, we produced poly(dopamine) (PDA) films with engineered patterns for improved cell adhesion. The patterned films were synthesized via the polymerization of dopamine at the air-water interface of a floating bed of spherical particles. Subsequent dissolution of the particles yielded free-standing PDA films with tunable geometrical patterns. Our results show that these patterned PDA films significantly enhance the adhesion of both cancer cells and stem cells, thus showing promise as substrates for cell attachment for various biomedical applications.
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