Surgery (St Vincent's) - Research Publications

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The effect of mindfulness training prior to total joint arthroplasty on post-operative pain and physical function: study protocol for a randomised controlled trial

Dowsey, Michelle M.; Castle, David J.; Knowles, Simon R.; Monshat, Kaveh; Salzberg, Michael R.; Choong, Peter F. M. (BIOMED CENTRAL LTD, 2014-06-01)

Background: Osteoarthritis is a leading cause of disability in developed nations. In Australia it afflicts 16.5% of the adult population. Total joint arthroplasty is considered the treatment of choice for end stage ...

Risk factors for superficial wound complications in hip and knee arthroplasty

Carroll, K.; Dowsey, M.; Choong, P.; Peel, T. (WILEY-BLACKWELL, 2014-02-27)

Superficial wound complications have been consistently implicated in the development of prosthetic joint infection. This cohort study aimed to determine perioperative risk factors associated with superficial wound ...

Poised Chromatin at the ZEB1 Promoter Enables Breast Cancer Cell Plasticity and Enhances Tumorigenicity

Chaffer, Christine L.; Marjanovic, Nemanja D.; Lee, Tony; Bell, George; Kleer, Celina G.; Reinhardt, Ferenc; D'Alessio, Ana C.; Young, Richard A.; Weinberg, Robert A. (CELL PRESS, 2013-07-27)

The recent discovery that normal and neoplastic epithelial cells re-enter the stem cell state raised the intriguing possibility that the aggressiveness of carcinomas derives not from their existing content of cancer stem ...

Cell Plasticity and Heterogeneity in Cancer

Marjanovic, Nemanja D.; Weinberg, Robert A.; Chaffer, Christine L. (AMER ASSOC CLINICAL CHEMISTRY, 2013-01-27)

BACKGROUND: Heterogeneity within a given cancer arises from diverse cell types recruited to the tumor and from genetic and/or epigenetic differences amongst the cancer cells themselves. These factors conspire to create a ...

Outcomes following large joint arthroplasty: does socio-economic status matter?

Dowsey, Michelle M.; Nikpour, Mandana; Choong, Peter F. M. (BIOMED CENTRAL LTD, 2014)

Background: We sought to determine whether socio-economic status (SES) is an independent predictor of outcome following total knee (TKR) and hip (THR) replacement in Australians.Methods: In this prospective cohort study, ...

Poised with purpose Cell plasticity enhances tumorigenicity

Marjanovic, Nemanja D.; Weinberg, Robert A.; Chaffer, Christine L. (LANDES BIOSCIENCE, 2013)

Enhanced liver progenitor cell survival and differentiation in vivo by spheroid implantation in a vascularized tissue engineering chamber

Yap, KK; Dingle, AM; Palmer, JA; Dhillon, RS; Lokmic, Z; Penington, AJ; Yeoh, GC; Morrison, WA; Mitchell, GM (2013)

Assessment of gene expression of intracellular calcium channels, pumps and exchangers with epidermal growth factor-induced epithelial-mesenchymal transition in a breast cancer cell line

Davis, FM; Parsonage, MT; Cabot, PJ; Parat, M-O; Thompson, EW; Roberts-Thomson, SJ; Monteith, GR (BIOMED CENTRAL LTD, 2013-07-29)

BACKGROUND: Epithelial-mesenchymal transition (EMT) is a process implicated in cancer metastasis that involves the conversion of epithelial cells to a more mesenchymal and invasive cell phenotype. In breast cancer cells ...

The utility of outcome measures in total knee replacement surgery.

Dowsey, MM; Choong, PFM (2013)

Total knee replacement (TKR) is the mainstay of treatment for people with end-stage knee OA among suitably "fit" candidates. As a high cost, high volume procedure with a worldwide demand that continues to grow it has become ...

Microbiological investigation of retrodiscal tissues from patients with advanced internal derangement of the temporomandibular joint

McIntosh, M; Dimitroulis, G (CHURCHILL LIVINGSTONE, 2012-03-01)

The aim of this study was to investigate the presence of bacteria in samples of retrodiscal tissues taken from patients suffering from advanced internal derangement of the temporomandibular joint (TMJ). 12 fresh retrodiscal ...

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